Super-size flies.

Meghana M Kulkarni; Norbert Perrimon

doi:10.1016/j.cmet.2005.04.008

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PubMed · 16054074

Super-size flies.

Meghana M Kulkarni·Norbert Perrimon

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Abstract

The increasing prevalence of obesity and other nutrition-related chronic diseases has prompted considerable efforts to understand their pathogenesis and treatment. One experimental approach is to overexpress, inactivate, or manipulate specific genes that regulate energy metabolism and fat storage. Many such techniques are fully established, routine tools in Drosophila and C. elegans, which provide elegant models for dissecting endocrine problems and metabolic pathways.

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Animals Humans Caenorhabditis elegans Drosophila melanogaster Energy Metabolism Fats Lipase Obesity Recombinant Proteins Journal Article Comment

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Meghana M Kulkarni, Norbert Perrimon. 2005. Super-size flies.. https://doi.org/10.1016/j.cmet.2005.04.008

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