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Biomedical subjects

H Ohtsuka

Publications and source records attributed to H Ohtsuka.

At least 163 records · Page 9Linked to original sources
PubMed1985

Bilateral cryptophthalmos with multiple associated congenital malformations.

An infant girl manifesting bilateral cryptophthalmos with multiple associated malformations was followed from birth. The globes were almost covered by a fold of skin and the findings were interesting in regard to the etiology of cryptophthalmos. The other congenital deformities included scaphocephaly, somewhat low-set ears, accessory tragi, a high arched palate, and funnel chest. The child was operated on at the age of 4 months with relatively satisfactory results, although she died suddenly of acute heart failure 4 months postoperatively.

Abnormalities, Multiple↗
PubMed1985

One-stage lip-switch operation.

A one-stage lip-switch operation was successfully performed on an 80-year-old woman with accompanying disorders. Postoperative venous congestion was controlled mainly by dressing changes with wet gauze.

Aged↗
PubMed1985

The effects of cromolyn sodium on the nasal mast cells.

To elucidate the characteristics of two different kinds of nasal mast cells, ie, the mucosal mast cells (MMC) and connective tissue mast cells, we examined the inhibitory effects of cromolyn sodium (CS) on in vitro allergen-induced histamine release from the nasal mast cells. The pharyngeal mast cells were also examined as control. Nasal scrapings (containing mainly MMC) were faintly sensitive to CS, whereas both the chopped nasal mucosas without epithelial layer and chopped pharyngeal mucosas (containing mostly connective tissue mast cells) were markedly sensitive in patients with allergic rhinitis. This result indicates that there are at least two distinct types of mast cells in allergic nasal mucosa, and the nasal MMC are insensitive to CS.

Cromolyn Sodium↗
PubMed1985

Studies of nasal surface basophilic cells.

Nasal surface basophilic cells (NSBC), located in both the mucosal and epithelial layer of the human nasal mucous membrane, were studied to elucidate whether or not they are one kind of mucosal mast cells (MMC). Nasal scrapings were collected and used as specimen of NSBC. The results demonstrate that NSBC had functional properties common to MMC in their response to antigen, formalin and compound 48/80.

Allergens↗
PubMed1985

Ultrastructural heterogeneity of the basophilic cells in the allergic nasal mucosa.

Basophilic cells in scrapings and pieces of nasal mucosa removed from the inferior turbinates of adult patients with house dust nasal allergy plus pieces of the oral mucosa from normal persons were examined electron microscopically. Three distinct types of basophilic cells, ie, blood basophil leukocytes (predominantly in the subepithelium), mucosal mast cells (predominantly in the epithelium), and connective tissue mast cells (predominantly in the deeper lamina propria) were identified in the nose.

Basophils↗
PubMed1984

Reconstruction of a large lateral abdominal wall defect with an ilio-lumbar bi-pedicled flap.

An ilio-lumbar bi-pedicled flap was used for the reconstruction of a large lateral abdominal wall defect with a fascia lata graft to provide the musculo-fascial layer. This flap is simple and safe because it includes both the superficial circumflex iliac vessels and the perforating cutaneous branches of the lumbar vessels. We regard it as the method of choice in the repair of major defects of the lateral abdominal wall.

Abdominal Muscles↗
PubMed1984

Folded skin with lipomatous nevus in the forehead and scalp.

An 18-year old Japanese woman with folded skin in the forehead and scalp was found to have an underly Brachycephaly with peculiar hair lines, broad and sparse eyebrows, bilateral epicanthi, and decreased neck-shoulder angles were found, as well as reticular pigmentation of fingers and toes. Routine laboratory data and endocrine analyses were within normal limits. Combined longitudinal and coronal incisions in the forehead and scalp initially, followed by gull-wing incisions along the eyebrows, resulted in satisfactory improvement of the clinical appearance.

Adolescent↗
PubMed1983

Intestinal absorption and urinary excretion of antitumor peptidomannan KS-2 after oral administration in rats.

A peptidomannan fraction designated as KS-2 was subjected for distribution study after oral administration. KS-2, exhibiting antitumor- and interferon-inducing action, was isolated from hot water extracts of mycelia of Basidiomycetes. For this purpose, KS-2 was labelled with fluorescein isothiocyanate. The amount and location of the labelled KS-2 (F-KS) was determined quantitatively by fluorescence intensity, and the molecular sizes were estimated by the fluorescence polarization method. The present data indicated that F-KS, when given orally, was absorbed partially via portal vein and intestinal lymphatics into the general circulation with intact molecular size. Moreover, F-KS was recovered in urine with concomitant breakdown in molecular weight. Histological evaluation revealed that F-KS was accumulated in the mesenteric lymph nodes, Peyer's patches, spleen, liver, and kidneys. These findings provide evidence that the polysaccharide KS-2 becomes accessible to the immune tissues and the vascular system; thus it may exert potentiating activity of defense system.

Administration, Oral↗
PubMed1983

Restriction endonuclease cleavage analysis of adenovirus type 8: two new subtypes from patients with epidemic keratoconjunctivitis in Sapporo, Japan.

We studied the restriction endonuclease cleavage patterns of DNAs of adenovirus type 8 (Ad 8) isolated from epidemic keratoconjunctivitis cases. DNAs of 25 Ad 8 isolates collected during the period from 1975 to 1981 in Sapporo were subjected to enzymatic cleavage with PstI, BamHl , HindIII and SalI. On the basis of the cleavage patterns, the isolates were divided into two subtypes, A and B, both different from Trim strain used as the Ad 8 prototype strain. Subtype A was prevalent in the period from 1975 to 1978, while subtype B in the period from 1976 to 1981.

Adenoviridae Infections↗
PubMed1983

Nasal histamine sensitivity in allergic rhinitis.

Our recent studies of nasal histamine sensitivity in nasal allergy are presented. The sensitivity differed according to the site and size of the nasal mucosa and was correlated with the degree of provocation reaction to antigen. This sensitivity appears to be established in childhood and strongly correlated with the increased sensitivity of histamine receptors as well as the autonomic nervous system dysfunction of the nose.

Adolescent↗