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PubMed · 803385

Necrotizing enterocolitis.

I D Frantz·P L'heureux·R R Engel·C E Hunt
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Abstract

The clinical course of 54 patients with necrotizing enterocolitis has been compared to a matched group of 98 control patients. On the day of life that NEC occurred, all 54 NEC patients and 63% of controls were receiving standard formula feedings, both at 80/cal/kg/day. Stool cultures at the time revealed a significantly increased frequency of Klebsiella in NEC as compared to control patients. Our data suggest that the combined presence of certain intestinal bacteria and enteric feedings, perhaps requiring a background of mucosal ischemia, may be of etiologic significance in the development of NEC and its radiologic hallmark, pneumatosis intestinalis.

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Birth WeightDisseminated Intravascular CoagulationEnterobacteriaceaeEnterocolitis, PseudomembranousFecesGestational AgeHumansInfant FoodInfant, NewbornInfant, Newborn, DiseasesInfant, Premature, DiseasesIntestinesKlebsiellaNecrosisParenteral NutritionRadiographyJournal Article

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I D Frantz, P L'heureux, R R Engel, C E Hunt. 1975. Necrotizing enterocolitis.. https://doi.org/10.1016/s0022-3476(75)80485-9

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