Ferromagnetic embolization. Experimental evaluation.

J W Barry; J J Bookstein; J F Alksne

doi:10.1148/radiology.138.2.7455113

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PubMed · 7455113

Ferromagnetic embolization. Experimental evaluation.

J W Barry·J J Bookstein·J F Alksne

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Abstract

Flow of embolized carbonyl iron particles under the influence of a magnetic field was evaluated in vitro and in vivo. The magnetic force caused particles to form aggregates, obstructing tubing or vascular beds. In dogs, 0.5 cc of iron particles injectged into a renal artery under magnetic control caused total occlusion and necrosis; injection without magnetic control caused little damage and no change in function. There was little systemic toxicity. Injection of iron particles under magnetic control may be helpful in embolic arterial occlusion and localized irradiation, hyperthermia, and chemotherapy.

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Animals Diatrizoate Dogs Embolization, Therapeutic In Vitro Techniques Iron Iron Carbonyl Compounds Kidney Kidney Diseases Magnetics Models, Biological Organometallic Compounds Rabbits Radiography Renal Artery Journal Article

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J W Barry, J J Bookstein, J F Alksne. 1981. Ferromagnetic embolization. Experimental evaluation.. https://doi.org/10.1148/radiology.138.2.7455113

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