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PubMed · 16950150

Synaptic vesicles: half full or half empty?

Thomas S Hnasko·Robert H Edwards
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Abstract

The regulation of quantal size through pre- rather than postsynaptic mechanisms has recently received considerable attention as a potential mechanism for plasticity. Vesicular transporters catalyze the filling of synaptic vesicles with transmitter and are thus potential substrates for such presynaptic regulation. In this issue of Neuron, Prado et al. pursue this line of investigation and show that changes in transporter expression that alter quantal size can affect behavior.

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AnimalsHumansNeurotransmitter AgentsSynaptic TransmissionSynaptic VesiclesVesicular Transport ProteinsCommentJournal ArticleReview

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Thomas S Hnasko, Robert H Edwards. 2006-09-07. Synaptic vesicles: half full or half empty?. https://doi.org/10.1016/j.neuron.2006.08.019

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