[Cytotoxic T cell].

Ge Ma; Li-ping Zhu; Wei Zhang

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PubMed · 12905673

[Cytotoxic T cell].

Ge Ma·Li-ping Zhu·Wei Zhang

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Abstract

Cytotoxic T cell (CTL) covers several subtypes, which are CD8+, CD4 and CD4-CD8-. CTL derives from T cell repertoire in lymphoid hematopoietic stem cells. It matures in thymus and is activated in peripheral lymphoid tissues. Effector CTL kills the target cells by 2 ways. One is apoptotic effect mediated by FasL-Fas pathway and the other one is cytolytic effect mediated by granzymes. CTL has aroused great attention due to its significance in anti-tumor and anti-virus.

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Animals Fas Ligand Protein Humans Membrane Glycoproteins Perforin Pore Forming Cytotoxic Proteins T-Lymphocytes, Cytotoxic fas Receptor Journal Article

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Ge Ma, Li-ping Zhu, Wei Zhang. 2002. [Cytotoxic T cell].. https://pubmed.ncbi.nlm.nih.gov/12905673/

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