Membrane fusion.

Reinhard Jahn; Helmut Grubmüller

doi:10.1016/s0955-0674(02)00356-3

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Membrane fusion.

Reinhard Jahn·Helmut Grubmüller

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Abstract

Fusion of biological membranes is governed by physical principles but it is unclear whether the transition states are primarily determined by lipid physics or by protein-lipid interactions. Recent advances in the field include the physical description of bilayer fusion, particularly new models beyond continuum models and the role of the SNARE proteins. Despite substantial progress, an integrated concept for protein-mediated membrane fusion is not yet available, and many open questions remain to be answered.

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Animals Cell Fusion Cell Membrane Humans Lipid Bilayers Membrane Fusion Membrane Proteins Models, Biological Physical Phenomena Physics SNARE Proteins Vesicular Transport Proteins Comparative Study Journal Article Research Support, Non-U.S. Gov't Review

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Reinhard Jahn, Helmut Grubmüller. 2002. Membrane fusion.. https://doi.org/10.1016/s0955-0674(02)00356-3

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