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Heterosynaptic LTP in early development.

C Chen
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Abstract

The formation of precise synaptic connections in the developing central nervous system involves activity-dependent control of synaptic strength. Correlated activity between the afferent input and postsynaptic neuron strengthens connections through long-term potentiation (LTP), while uncorrelated synaptic inputs are selectively diminished. In this issue of Neuron, Tao et al. report that LTP in young animals has less synaptic specificity than in older animals, indicating that the properties of LTP change during development.

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AnimalsCentral Nervous SystemLong-Term PotentiationSynapsesCommentJournal ArticleReview

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C Chen. 2001-08-30. Heterosynaptic LTP in early development.. https://doi.org/10.1016/s0896-6273(01)00405-6

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