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Biomedical subjects

Y Yasui

Publications and source records attributed to Y Yasui.

At least 217 records · Page 12Linked to original sources
PubMed1985

[The clinical significance of CA125 in patients with gynecological tumors--a comparative study on CA125 and other tumor markers].

Serum CA125 levels were measured by radioimmunoassay patients with various gynecological tumors. Elevated levels of CA125 were detected in the serum of patients with malignant ovarian tumors. Among patients with uterine tumors, CA125 levels were elevated in those with malignant uterine tumors, but not with uterine myomas. The correlations between tumor markers (CA125, IAP, ferritin, PTA) and malignant ovarian tumors were measured, and only CA125 levels were found to correlate with progression or regression of the disease in patients with malignant ovarian tumors. These results suggest that CA125 may be a useful marker for monitoring the response to treatment in patients with malignant ovarian tumors.

Adenocarcinoma↗
PubMed1984

An anterograde-retrograde transneuronal transport of conjugates of wheat germ agglutinin with horseradish peroxidase (WGA-HRP): labeling of neurons in the reticular nucleus of the thalamus with WGA-HRP injected into the posterior column nuclei in the cat.

Neuronal cell bodies in the reticular thalamic nucleus (R) were labeled with wheat germ agglutinin-conjugated horseradish peroxidase (WGA-HRP) which was injected contralaterally into the posterior column nuclei (PCN) in the cat. The tracer was assumed to be transported to the posterolateral ventral thalamic nucleus (VPL), where it could escape from axon terminals of the PCN neurons and then be taken up by axon terminals of R neurons to label retrogradely the cell bodies of the R neurons.

Animals↗
PubMed1984

Distribution of premotor neurons for the hypoglossal nucleus in the cat.

After injecting horseradish peroxidase into the hypoglossal nucleus, labeled neuronal cell bodies were constantly seen bilaterally with a slight ipsilateral dominance in the parvocellular reticular formation and reticular regions around the hypoglossal nucleus, ipsilaterally in the nucleus of Kölliker-Fuse, and contralaterally within the hypoglossal nucleus. A few labeled neurons were often found bilaterally with an ipsilateral dominance in the inter- and supratrigeminal regions around the motor trigeminal nucleus, parabrachial nucleus, ventral portions of the medial reticular formation of the pons and medulla oblongata, and dorsal tegmental regions and central gray of the midbrain.

Animals↗
PubMed1984

Distribution of premotor neurons for orbicularis oculi motoneurons in the cat, with particular reference to possible pathways for blink reflex.

After injecting horseradish peroxidase into the facial nucleus regions containing orbicularis oculi motoneurons, labeled neuronal cell bodies were found in the lateral medullary reticular formation, pretectal olivary nucleus, sensory trigeminal nuclei, lateral and medial parabrachial nuclei, ventromedial reticular formation medial to the facial nucleus, red nucleus and its surroundings, anterior horn of the upper cervical cord, medullary raphe nuclei, oculomotor nucleus and its surroundings, nuclei of Darkschewitsch, Cajal and Edinger-Westphal, ventral part of the midbrain central gray, pontine tegmentum, lateral vestibular nucleus and deep layers of the superior colliculus.

Animals↗
PubMed1984

Trigeminal primary afferent neurons projecting directly to the solitary nucleus in the cat: a transganglionic and retrograde horseradish peroxidase study.

After applying horseradish peroxidase to peripheral branches of the trigeminal nerve in the cat, the lingual and pterygopalatine nerves were found to contain fibers which ended ipsilaterally in the rostral portions of the solitary nucleus (SN); massively in the medial and ventrolateral SN, moderately in the intermediate and interstitial SN and sparsely in the ventral SN. The rostralmost part of the SN was free from labeled terminals. After injecting the enzyme into the SN portions rostral to the area postrema, small neurons were scattered in the maxillary and mandibular divisions of the trigeminal ganglion.

Animals↗
PubMed1984

Direct projections from the substantia nigra to the posterior thalamic regions in the cat.

The substantia nigra (SN) of the cat was shown, by the anterograde and retrograde horseradish peroxidase methods, to contain neurons which send their axons to the caudomedial portions of the suprageniculate nucleus and/or lateroposterior nucleus of the thalamus; these neurons were located in the restricted region in the lateral part of the SN, which corresponds to the pars lateralis of the SN.

Afferent Pathways↗
PubMed1984

Projections from the parvocellular part of the posteromedial ventral nucleus of the thalamus to the lateral amygdaloid nucleus in the cat.

It was shown in the cat by anterograde and retrograde WGA-HRP methods that the medial portion of the parvocellular part of the posteromedial ventral nucleus of the thalamus (VPMpc-m) sent fibers ipsilaterally to the rostrodorsal part of the lateral amygdaloid nucleus (Al-rd). The regions of the orbital gyrus (OG), which were connected reciprocally with the VPMpc-m, were also observed to send fibers to the Al-rd. Thus the VPMpc-m was assumed to project to the Al-rd directly, and indirectly via the OG.

Amygdala↗
PubMed1983

The posteromedial ventral nucleus of the thalamus (VPM) of the cat: direct ascending projections to the cytoarchitectonic subdivisions.

The posteromedial ventral nucleus (VPM) of the cat is divided cytoarchitectonically into the magnocellular (VPMmc), lateral parvocellular (VPMpcl), and medial parvocellular (VPMpcm) divisions. Cell bodies of neurons in the VPMpcm are small, while those in the VPMpcl are small to medium-sized. The VPMmc contains large neurons. Direct projections from the lower brain stem structures to each of the three divisions of the VPM were examined by the retrograde horseradish peroxidase (HRP) method. When HRP injection was done into the VPMmc, labeled neurons were mainly located contralaterally in the ventral division of the principal sensory trigeminal nucleus (Vp), in the rostral part of the oral subnucleus in the spinal trigeminal nucleus (Vsp), and in the interpolar subnucleus of the Vsp; a few labeled neurons were also found contralaterally in lamina I of the caudal subnucleus of the Vsp. When HRP injection was restricted to the VPMpcl or VPMpcm, HRP-labeled neurons were mainly observed ipsilaterally, respectively, in the dorsal division of the Vp, or in the parabrachial nucleus (PBN) regions dorsomedial and ventromedial to the brachium conjunctivum. After HRP injection into the parvocellular part of the VPM (VPMpc), labeled neurons were also seen contralaterally in the Vsp, but these were far less numerous than those seen after HRP injections into the VPMmc. Thus, each of the three divisions of the VPM receives main ascending afferent fibers from different brain stem structures; the VPMpcm, VPMpcl, or VPMmc receives afferent fibers, respectively, from the PBN ipsilaterally, from the dorsal division of Vp ipsilaterally, or from the ventral division of the Vp and the Vsp contralaterally.

Afferent Pathways↗
PubMed1983

A pretectofacial projection in the cat: a possible link in the visually-triggered blink reflex pathways.

A direct projection from the pretectum to the facial motor nucleus was shown to exist in the cat by the anterograde and retrograde horseradish peroxidase (HRP) methods. Pretectofacial fibers arise from the olivary pretectal nucleus and end mainly in the dorsal division of the facial motor nucleus, bilaterally, with a contralateral predominance. It is known that the olivary pretectal nucleus receives retinal fibers, and that the dorsal division of the facial motor nucleus contains orbicularis oculi motoneurons. Thus, the pretectofacial fibers are assumed to cause protective lid closure with certain visual stimuli.

Animals↗
PubMed1983

Direct projections from the anterior pretectal nucleus to the dorsal accessory olive in the cat: an anterograde and retrograde WGA-HRP study.

Direct projections from the anterior pretectal nucleus (APN) to the dorsal accessory olive (DAO) were found in the cat by the anterograde and retrograde WGA-HRP methods. The dorsal or the ventral portions of the rostral half of the APN pars compacta send fibers respectively to the lateral or the medial portions of the whole rostrocaudal extent of the DAO. These APN-DAO fibers can be considered to play roles in some somatomotor mechanisms.

Animals↗
PubMed1983

A light and electron microscopic study of premotor neurons for the trigeminal motor nucleus.

Premotor neurons sending their axons to the trigeminal motor nucleus were observed in the cat by light and electron microscopy after labeling the neurons retrogradely or anterogradely with horseradish peroxidase (HRP). After HRP injection into the trigeminal motor nucleus, retrogradely labeled neurons were seen most frequently in the parvocellular reticular formation bilaterally. Many labeled neurons were also seen contralaterally in the intermediate zone at the rostralmost levels of the cervical cord and its rostral extension into the caudalmost levels of the medulla oblongata. Additionally, some neurons were labeled ipsilaterally in the mesencephalic trigeminal nucleus, contralaterally in the main sensory trigeminal nucleus and the trigeminal motor nucleus, and bilaterally in the oral and interpolar subnuclei of the spinal trigeminal nucleus. Only a few labeled neurons were seen in the confines of the gigantocellular reticular formation. All labeled neurons were small or of medium size; no large neurons were labeled. After HRP injection into the regions around the trigeminal motor nucleus or the parvocellular reticular formation, axodendritic terminals containing HRP granules were found contralaterally within the trigeminal motor nucleus. Some of these labeled terminals were filled with round synaptic vesicles and others contained pleomorphic synaptic vesicles. The varied morphology of labeled axon terminals was considered to reflect the functional heterogeneity of the premotor neurons for the trigeminal motor nucleus.

Animals↗