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Biomedical subjects

Y Yasui

Publications and source records attributed to Y Yasui.

At least 235 records · Page 13Linked to original sources
PubMed1983

Structural specificity of aromatic compounds with special reference to mutagenic activity in Salmonella typhimurium--a series of chloro- or fluoro-nitrobenzene derivatives.

The mutagenicity of 21 chloro- or fluoronitrobenzene compounds and 9 chloro- or fluorobenzene compounds in Salmonella typhimurium (strains TA98, TA1538, TA1537, TA100 and TA1535) was examined. The tests were carried out under the conditions of absence and presence of liver microsomal activation. 15 nitro-group compounds had mutagenic activity; above all, compounds of fluoronitrobenzene were mutagenic for both types of strain. On the other hand, chloronitrobenzene compounds were mutagenic for base-pair substitution strains only. Mutagenic activity was exhibited by all compounds having a chloro or fluoro substituent at the para and ortho position in the nitrobenzene nucleus. All compounds without a nitro substituent showed no mutagenic activity.

Animals↗
PubMed1983

Identification of a mutagenic substance, in Rubia tinctorum L. (madder) root, as lucidin.

Mutagenicity of the extract from Rubia tinctorum L. (madder) root was demonstrated on Salmonella typhimurium TA100 and TA98. The active substance wa purified and characterized by TLC, UV spectrum, IR spectrum, mass spectrum and [1H]NMR spectrum. All the mutagenic activity of the extract from the root of Rubia tinctorum L. was due to lucidin (1,3-dihydroxy,2-hydroxymethyl-9, 10-anthraquinone).

Anthraquinones↗
PubMed1982

Identification of motoneurons supplying the tensor veli palatini muscle in the guinea pig and cat: an horseradish peroxidase study.

Identification of motoneurons supplying the tensor veli palatini muscle was attempted by the horseradish peroxidase (HRP) method in the guinea pig and cat. After HRP injection into the tensor veli palatini muscle, HRP-labeled neurons were seen in the regions closely medial to the cluster of the lateral pterygoid motoneurons in the dorsolateral division of the trigeminal motor nucleus. In the guinea pig the tensor veli palatini motoneurons were observed at the level of the whole rostrocaudal extent of the trigeminal motor nucleus, while in the cat they were seen at the level of the rostral two-thirds of the nucleus.

Animals↗
PubMed1982

Localization of motoneurons innervating the tensor tympani muscles: an horseradish peroxidase study in the guinea pig and cat.

Motoneurons innervating the tensor tympani muscle were identified in the adult guinea pig and cat by the horseradish peroxidase (HRP) method. After HRP injection into the tensor tympani muscle, HRP-labeled neurons were seen in the regions outside the cytoarchitectonically-defined confines of the trigeminal motor nucleus; in the regions rostral to the rostral pole of the nucleus, as well as in the regions ventral and ventrolateral to the nucleus at the levels of the rostral half (guinea pig) or the rostral two-thirds (cat) of the nucleus. The tensor tympani motoneurons were generally smaller than the masticatory motoneurons.

Animals↗
PubMed1982

Localization of masticatory motoneurons in the trigeminal motor nucleus of the guinea pig.

The myotopical arrangement of masticatory motoneurons was examined in the guinea pig by the horseradish peroxidase method. The trigeminal motor nucleus was composed of dorsolateral and ventromedial divisions; the former was seen in the whole rostrocaudal extent of the nucleus, while the latter was present at levels of the caudal two thirds of the nucleus. The jaw-closer motoneurons were located in the dorsolateral division, and the jaw-opener motoneurons (mylohyoid and anterior digastric motoneurons) were seen in the ventromedial division.

Animals↗
PubMed1982

Direct projections from the extrathalamic forebrain structures to the neocortex in the macaque monkey.

Extrathalamic direct projections from the subcortical forebrain structures to the neocortex were examined in the macaque monkey by the horseradish peroxidase method. The enzyme, when injected into discrete regions in the neocortex, labeled cell bodies of extrathalamic forebrain neurons in the basal nucleus of Meynert, nucleus of the diagonal band, medial septal nucleus, hypothalamus, claustrum and dorsolateral part of the basal amygdaloid nucleus. Neurons in the basal nucleus of Meynert, lateral hypothalamus and claustrum appeared to send their axons widely, but not diffusely, to the neocortex.

Animals↗