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Biomedical subjects

Y Yassur

Publications and source records attributed to Y Yassur.

At least 127 records · Page 7Linked to original sources

Pupil cycle time in space occupying lesions of anterior optic pathways.

Twenty-nine patients with presumed compressive optic neuropathy were studied, and pupil cycle times were measured. We found (1) normalcy of the test in cases of space-occupying lesion without suprasellar extension or after successful operation; (2) prolongation of pupil cycle time in cases of subclinical disorder conformed by visual evoked responses as well; (3) a good correlation between the values of prolonged pupil cycle time and degree of involvement of the visual field in pathological cases.

Eye Neoplasms↗

Narrow-band (540NM) green-light stereoscopic photography of the surface details of the peripapillary retina.

We used narrow-band (540-nm) green-light stereoscopic fundus photography to study the surface details of the peripapillary retina in 14 patients. Each photograph was divided into four areas; the papillomacular bundle, the upper arcuate bundle, the lower arcuate bundle, and the nasal sectorial fibers. We scored each area on a scale of 0 (normal) to 3 (total loss of nerve fiber layer), and compared these scores to those obtained by testing the corresponding visual fields. The scores were the same in 88 of 111 comparisons; the retinal scores were higher in 17 comparisons and the visual field scores were higher in six comparisons. This photographic technique makes the nerve fiber layer easier to see and evaluate and the detection of defects becomes less difficult.

Adolescent↗

Treatment of macular subretinal neovascularization with the red-light krypton laser in presumed ocular histoplasmosis syndrome.

A patient with presumed ocular histoplasmosis and decreased visual acuity in one eye had subretinal neovascularization and retinal hemorrhage in the macular area. Argon-laser treatment to eradicate the subretinal neovascular membrane was contraindicated because of the proximity of the hemorrhagic lesion to the fovea. We used a red-light krypton laser (647 nm) because the light is not absorbed by the hemoglobin in the retinal hemorrhage or by the macular luteal pigment (xanthophyll), and because it is transmitted into the choroid, allowing treatment within the macular zone with less damage to the internal retinal elements. After treatment, the subretinal neovascular membrane completely disappeared and the macular hemorrhage cleared. To the best of our knowledge, this is the first time that a histoplasmic macular subretinal neovascular membrane has been treated with the red-light krypton laser.

Eye Diseases↗

Surgical management of retinal detachment without cryopexy.

A clinical study of eyes with rhegmatogenous retinal detachment compared the reattachment rate in two groups of eyes: in the control group, cryopexy was applied over the retinal breaks during surgery; in the test group, cryopexy was not applied. There was a similar rate of retinal reattachment in the two groups in the immediate postoperative period. However, during the long follow-up period (36 months) there was a considerable difference in the two groups. Eyes that had undergone cryopexy had a lower rate of redetachment than eyes that had not. The rate of operative and postoperative complications was low in both groups, except for periretinal proliferation, which was more frequent in the test group. These results suggest that cryopexy may lower the incidence of redetachment after retinal detachment surgery.

Cryosurgery↗

Bilateral maculopathy simulating 'cherry-red spot' in a patient with Crohn's disease.

A 23-year-old man suffering from Crohn's disease developed a bilateral maculopathy simulating 'cherry-red spot' with vision impairment and normal electroretinogram during total parenteral hyperalimentation, when copper and zinc serum levels were considerably decreased. The maculopathy rapidly subsided after cessation of the parenteral hyperalimentation and the addition of cooper and zinc. The cause of this maculopathy may be ocular involvement as part of the systemic disease owing to storage of the supplementary free amines and intravenous lipids, and the deficiency of zinc and copper.

Adult↗

Treatment of acute retrolental fibroplasia by cryopexy.

Fifteen to 20% of premature infants weighing below 1500 g develop variable degrees of acute retrolental fibroplasia (RLF). Approximately 5% of those infants who develop RLF can be expected to become blind. A prospective study was carried out to evaluate if early cryopexy can prevent this blindness. The study showed that, among 533 infants admitted to the neonatal intensive care unit between July 1976 and December 1978, 55 had some degree of active RLF. In 18 eyes of 9 infants in whom the retinopathy progressed beyond active stage II cryopexy treatment was applied to the avascular retina. In all the treated eyes the active retinopathy regressed, and there were no complications due to the procedure. The long-term follow-up showed that in 15 eyes there was good vision and that the remaining 3 eyes had some impairment of vision but were not blind. These results suggest that cryotherapy may prove useful in treating premature infants with RLF who show progression of their active stage, without the danger of further visual loss or complete blindness.

Acute Disease↗

Optic disc neovascularisation in diabetic retinopathy: I. A system for grading proliferation at the optic nerve head in patients with proliferative diabetic retinopathy.

An anatomical taxonomy for neovascular proliferation of the optic nerve head in patients with proliferative diabetic retinopathy is presented. The technique consists in comparing (A) number of involved quadrants, (B) calibre of vessels, (C) neovascular density, (D) neovascular area, (E) plane of proliferation, and (F) fluorescein angiographic findings. A similar taxonomy is used to describe fibrous tissue proliferation at the disc. With these criteria a series of standard photographs have been utilised in a numerical grading system. This system has proved useful in documenting the natural history and response to photocoagulation therapy for diabetic disc neovascularisation.

Diabetic Retinopathy↗

Optic disc neovascularisation in diabetic retinopathy: II. Natural history and results of photocoagulation treatment.

A follow-up study on 67 diabetic patients with new proliferation on the nerve head (neovascularisation of the disc and fibrous proliferation of the disc) was carried out for 4 years. The patients were randomly assigned for treatment with argon laser and xenon photocoagulation in only one eye, with the other eye serving as a control. The disc condition was periodically evaluated for NVD, FPD, and for the relations between them according to a grading taxonomy which was previously established. It was found that there were significant differences in NVD and FPD evolution between treated and untreated eyes. The various parameters concerned with these differences were observed, analysed, and correlated.

Adolescent↗

Rubella maculopathy.

Three patients with known history of congenital rubella and sudden decrease of vision are presented. Two of the 3 patients had previous eye examinations which showed typical rubella (salt and pepper) retinopathy. All 3 showed macular lesions associated with presumed subretinal neovascularisation.

Child↗

Clinical method for measurement of light backscattering from the in vivo human lens.

A simple clinical method for measurement of light backscatter from defined regions of the lens in vivo is described. Light scattering was quantitated in 168 lenses of 85 "normal" subjects spanning 8 decades of life. The results indicate that light scatter from the anterior capsule does not change with age. The light scatter from the anterior cortex is quite significant even in young lenses and gradually increases with age. The backscatter in the nuclear region is minimal in young eyes, increasing gradually up to the age of 40, after which it exhibits a sharp increase.

Adolescent↗

Laser iridotomy in closed-angle glaucoma.

An argon laser iridotomy was performed on 53 eyes of 34 patients with closed-angle glaucoma. Technically, all of the iridotomies were successful. Blue irides were more resistant to treatment than brown irides. The iridotomies were performed with high energy of 2 W and a very short exposure time of 0.01 to 0.04 s, thus minimizing thermal damage to adjacent tissues. Patients with narrow angles who underwent preventive laser irodotomy benefited most from the procedure, and all the eyes of this group maintained a normal intraocular pressure (IOP) after the iridotomy. Of the 20 eyes with acute angle-closure glaucoma, 17 maintained a normal IOP after iridotomy, and only three were resistant to this treatment, calling for filtering operations later. The IOP of eyes with chronic closed-angle glaucoma did not change after the procedure, and the iridocorneal angles remained practically the same. Argon laser iridotomy by this technique is highly recommended as the procedure of choice for eyes with acute angle-closure glaucoma and for preventive iridotomy in the fellow eye. The procedure is simple, is performed in the outpatient clinic, and engenders no major complications.

Follow-Up Studies↗