[Ocular damage in the laser industry].
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Biomedical subjects
Publications and source records attributed to Y Yassur.
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A comprehensive glaucoma screening of residents of three urban areas in southern Israel, aged 40 years and above, was performed between 1982 and 1984. Among other factors tested, intraocular pressure (IOP) and refractive status were recorded and the association between them was analyzed. Information on both factors was available in 2,403 (4,821 eyes) of the 2,594 persons participating. There were significantly more myopes among persons with IOPs of more than 20 mm Hg than with lower IOPs. Mean IOP increased gradually from 14.19 mm Hg in hypermetropes to 16.00 mm Hg among high myopes. Furthermore, the association between refractive status and IOP was stronger among Jews of North African or Asian origin than among Jews of European origin.
Factors influencing the long-term cure of 116 consecutive cases of acute angle-closure glaucoma, with at least one year's follow-up were examined. Delay in presentation and the time needed to terminate the attack were found to have a detrimental effect on the final outcome, while the height of the intraocular pressure at the time of the attack was found to be unimportant in predicting the long-term prognosis of the disease.
126 cases of acute angle-closure glaucoma were encountered in the total population of the Israel Negev region during 12 years. This constitutes an incidence of 4.2/100,000/year in the total population and 11.1/100,000 in the over-30 population. The female:male ratio was 2.1:1 and the most frequently affected age-group was the 51-60 one; when age adjustment was made for the total population, the risk was equally high for all ages above 50. The ethnic origin had no effect on the incidence. A statistically significant preponderance of attacks occurring during summer and winter was found.
A highly sensitive solid phase radioimmunoassay (RIA) was adapted for determination of herpes simplex virus (HSV) specific IgA antibodies in lacrimal fluids. The RIA procedure was applied to examine HSV IgA antibodies in serial samples of lacrimal fluid and in sera from 14 patients with herpes keratitis. HSV-specific IgA antibodies were detected in the lacrimal fluid of the affected eye in 12 of the 14 patients. HSV IgA antibodies were also detected in the lacrimal fluid of the unaffected eye of 7 of these patients in titers lower than those found in the corresponding affected eye. Evidence for local HSV antibody production in lacrimal fluid in herpes keratitis was supported by examination for antibodies to the unrelated measles antigen. Detection of lacrimal fluid HSV IgA antibodies might be a useful adjunct in rapid diagnosis of herpes keratitis. The advantage of characterizing the local immune response as well as viral expression in the affected vs. the unaffected eye in the same individual as a model for understanding the factors leading to subclinical vs. clinical manifestations of recurrent ocular herpes virus infections will be discussed.
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Benign intracranial hypertension has been described in association with hormonal imbalance. We hereby present a rare case of transient, severe swelling of the optic discs during menarche, diagnosed as BIH.
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The syndrome of acquired immunodeficiency (AIDS) has previously been described. Originally thought to affect homosexuals and drug abusers exclusively, the disorder has also been observed in women associated with drug abuse, hemophiliacs, Haitians and, rarely, in heterosexual men. Several hundred cases have been reported in the United States whereas only a small number have been reported elsewhere. We report the first case of AIDS in Israel in a heterosexual male who developed the opportunistic infections of esophageal candidiasis and pneumocystis caranii pneumonia as well as the ischemic retinopathy which has come to be associated with the syndrome.
Serial narrow-band green-light fundus photographs documented the evolution of descending optic atrophy in a case of rapid bilateral blindness produced by a highly invasive osteogenic sarcoma of the base of the skull. Disappearance of the nerve fiber layer (NFL) was observed to take place between the sixth and 12th week after onset of blindness; thus, it is similar to the evolution of descending atrophy found to occur in clinical cases of blindness caused by traumatic involvement of the optic nerve. Parallel to the disappearance of the NFL there was an increase in optic nerve head excavation and a change in the appearance of the vessels on the disk surfaces.
One hundred and fifty-five premature infants weighing 600-2000 g were followed up during 1974-80 for the presence of retinopathy of prematurity (ROP) and for the existence of myopia. 50% of the premature infants who had ROP were myopic, while only 16% myopic premature infants were found among those who did not have ROP. There was a positive correlation between the degree of myopia and the severity of cicatricial ROP. No difference existed in the frequency and degree of myopia between premature infants in which ROP cicatrised spontaneously and in those where it cicatrised after cryopexy.
Fifty-seven eyes of 49 patients with senile retinoschisis were treated by argon laser photocoagulation and followed up for 3 to 6 years. In most of the treated eyes the retinoschisis either completely or partially collapsed and in none did the retinoschisis or loss of visual field progress further. No long-term complications due to the treatment were noted. In none of the treated eyes did retinal detachment develop. In view of this the indications at present for argon laser treatment in retinoschisis may be extended to include any case in which the retinoschisis progresses beyond the equator and visual field loss continues. This may prevent further visual field damage and other rare complications of slowly progressive retinoschisis and facilitate the many years' follow-up of elderly patients with retinoschisis who develop cataracts.
A high incidence of retinopathy of prematurity (ROP) was found in the very low-birth-weight infants discharged from the neonatal intensive care unit during the years 1977 to 1980, in spite of frequent monitoring of oxygen use. Although the yearly incidence of ROP in infants weighing less than 1,500 g varied between 35% to 36%, none were blind. The medical records of 65 infants with a birth weight between 501 and 1,250 g; surviving in 1979 to 1980, were reviewed in order to find risk factors for ROP. There were no significant differences between the 34 infants with ROP and the 31 infants who did not have ROP in mean birth weight or mean gestational age. Of 32 possible risk factors examined, the factors significantly associated with ROP were: apnea with mask and bag ventilation; prolonged parenteral nutrition; number of blood transfusions; and episodes of hypoxemia, hypercarbia, and hypocarbia. A highly significant association between hypocarbia and the development of severe ROP was found.
A case of a 17-year-old male suffering from acute bilateral disseminated subretinal inflammatory lesions, which affected the posterior pole and the retinal periphery as well, is presented. All the laboratory tests were negative except for the Sabin-Feldman dye test which showed a positive rising titer. The clinical course of the disease is described, and the differential diagnosis discussed.
Hereditary retinoschisis affected eight members of three generations of a family. The mode of transmission and the clinical features were not compatible with findings noted in either X-chromosome-linked or autosomal recessive forms of retinoschisis. The genetic and clinical features in this family strongly supported autosomal dominant inheritance, adding to the known genetic heterogeneity for the hereditary forms of retinoschisis. The expression of the condition varied in severity, but all affected members of the family had peripheral retinoschisis and peripheral retinal degeneration. Three had maculoschisis and five had macular pigmentary changes. Electroretinographic findings were normal in six of the eight.
Sixty-eight eyes with neovascular senile maculopathy involving the capillary free zone that were assigned randomly for red krypton laser photocoagulation were followed for two years and compared to 55 eyes with the same disease that were not treated. In the majority of the studied eyes there was a decline of visual acuity during the follow-up period. However, an increase in visual acuity was encountered in one third of treated eyes, but no increase in the untreated eyes. The extent of visual acuity deterioration was greater in the nontreated than in the treated eyes. Eyes that were treated when visual acuity was between 6/9-6/60 generally belonged to a better final visual acuity group than those eyes that were treated when visual acuity was less than 6/60. The technique of red krypton laser photocoagulation is described, the rationale for this treatment is discussed, and the results of the treatment are evaluated.
Pupil cycle time was found to correlate with the clinical findings in 24 patients with noncompressive optic nerve pathology, including 11 cases of multiple sclerosis. Furthermore, subclinical multiple sclerosis was detected by the prolongation of pupil cycle time and was confirmed by visual evoked potential analysis. There was a correspondence between dynamics in the clinical findings and the pupil cycle time in two cases of multiple sclerosis that were followed up.