[Studies on anti-ulcerogenic protein in inflamed rabbit skin tissues. III. Anti-ulcerogenic peptide (Gly-Ser-His-Lys) obtained from tissues infected with vaccinia virus].
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Biomedical subjects
Publications and source records attributed to Y Okazaki.
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HLA antigens were typed among 136 Japanese schizophrenics. Increased frequencies were seen in A9 (Aw24), A10 (A26) and Bw54, and decreased frequency in B40 antigens when compared to 187 Japanese controls. It is suggested that there may be an association between A9 (Aw24) and schizophrenia with a chronic-progressive course and also an association between A10 (A26) and hebephrenia.
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Twenty-four patients with gastric ulcer and 18 with duodenal ulcer diagnosed by endoscopy were treated with ranitidine, 300 mg day-1, for 8 consecutive weeks, or until the ulcer was found endoscopically healed. Of the 24 with gastric ulcer, 50% were healed within 4 weeks, and 83% within 8 weeks. Of 18 cases with duodenal ulcer, 50% were healed within 2 weeks and 94% within 4 weeks. Therapeutic effect of ranitidine was statistically significant compared with placebo. Side effects due to ranitidine administration were few and consisted of a rash in one case and slight increase of transaminase in a few patients.
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