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Biomedical subjects

Y Endoh

Publications and source records attributed to Y Endoh.

At least 91 records · Page 5Linked to original sources

[Clinical significance of manganese superoxide dismutase in ovarian carcinoma].

A monoclonal antibody to manganese superoxide dismutase (Mn-SOD) was measured in patients with epithelial ovarian carcinomas. An enzyme-linked immunosorbent assay has been developed to detect serum Mn-SOD. With this assay, only 0.9% of the 207 healthy females tested had more than 130 ng per milliliter of serum Mn-SOD. In contrast, 37 of 62 patients (59.7%) with epithelial ovarian carcinomas showed high levels of Mn-SOD. The serum Mn-SOD increased according to the clinical stage and declined to reflect the effects of therapy. Compared with CA-125, Mn-SOD showed a less frequent false positive rate (10%) in benign gynecological diseases. The determination of Mn-SOD levels proved to be a clinically useful marker for monitoring the response to treatment and to early detection of the recurrence of epithelial ovarian carcinomas.

Biomarkers, Tumor↗

[Productive aspergilloma on the inner wall of a cavity].

Fungus ball type pulmonary aspergilloma is easily recognizable on chest X-ray. This is a report on "productive aspergilloma on the inner wall of a cavity" (PAIC), named from our clinical experience in 1980, which grew to form aspergillus strata on partial or overall inner walls of the cavity. Our 5 cases with this type supported the existence of this type and revealed an 18% incidence in patients with pulmonary aspergilloma, characteristic clinical features and immunological reactions, thus pointing to the necessity of early diagnosis and treatment for this type of aspergilloma. The species of aspergillus cultured from the patients with this type of disease was Aspergillus fumigatus.

Adult↗

[Clinical features of traumatic diaphragmatic injuries with or without herniated visceral organs].

The difficulty of diagnosis and selection of operative approach in traumatic diaphragmatic injuries (T. D.I.) have been debated for a long time. The reason why these problems remain unsolved is possibly due to the inaccuracy in the definition of T.D.I. We propose to classify the T.D.I. into two categories; diaphragmatic rupture without herniated visceral organs (D.R.) and diaphragmatic hernia with herniated visceral organs (D.H.). Clinical features in these two groups (D.R. in 9 cases and D.H. in 11 cases) were compared and discussed as follows: 1) Intrathoracic injuries were associated in all cases of both groups, but intraabdominal injury was found in 90.9% of D.H., whereas 33.3% of D.R. 2) Diagnostic findings in chest X-ray were not observed in D.R., but frequently observed in D.H. 3) All cases of D.R. were operated through a single approach (transabdominal or transthoracic), but additional approach was necessary in 78% of D.H. It is considered that T. D.I. should be classify into D.R. and D.H. because T.D.I. with or without herniated visceral organs exhibit definitely different clinical features.

Abdominal Injuries↗