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Biomedical subjects

W Weiss

Publications and source records attributed to W Weiss.

At least 181 records · Page 10Linked to original sources
PubMed1982

A special form of segmental pancreatitis: "groove pancreatitis".

"Groove pancreatitis" is a form of segmental pancreatitis affecting the head of the pancreas which is localized within the "groove" between the head of the organ, the duodenum and the common bile duct. We diagnosed this form of pancreatitis in 30 out of 123 surgical duodenopancreatectomy specimens of chronic pancreatitis (24.4%). In a comparison with non-segmental chronic pancreatitis, no differences was observed in age and sex distribution or in alcohol consumption. Clinically, in contrast, preceding diseases of the biliary system, peptic ulcers and gastric resections were more frequently indicated. The cardinal clinical finding is frequently duodenal stenosis; in sonographic and CT examinations, the cicatricial "plate" in the "groove" represents as a "tumor", so that--also on account of the frequent duodenal stenosis--a carcinoma of the head of the pancreas may be suspected. In groove pancreatitis, the pancreatic duct system is grossly normal, calcifications or intraductal protein plugs being rare and an adaptive intimal fibrosis of the intrapancreatic arteries and arterioles is found only within the cicatricial area. Very commonly, scarring of the duodenal wall, stenosis of the duodenum, true duodenal wall and pancreatic cysts are detected. Aetiopathogenetic possibilities are previous diseases of the biliary system, peptic ulcers, gastric resections, true duodenal wall cysts, pancreatic head cysts, pancreatitis in duodenal pancreatic heterotopia, and disturbances of pancreatic juice outflow in Santorini's duct in the absence of the minor papilla, and hyperstimulation in consequence of chronic alcoholism.

Adult↗
PubMed1981

[Clinical experience with occult blood test in 8784 patients (author's transl)].

The faeces of 8784 patients were tested for occult blood, using the "Haemoccult-II" method. 347 (4.0%) gave at least one positive result. Endoscopic examination of the gastrointestinal tract was performed in 301 patients. In 62.8% of cases the lesion responsible for the bleeding was located in the lower gastrointestinal tract, in 17.6% in the upper gastrointestinal tract. In 19.6% no cause was found for the positive test. In 133 out of 301 haemoccult-positive patients (44.2%) tumours were identified as sources of bleeding. Our results were compared with the findings obtained with other screening programmes for colorectal carcinomas. Haemoccult-II test are recommended as a yearly routine procedure for early detection of colorectal tumours.

Adenoma↗
PubMed1981

[Working conditions, self-destructive behavior and well-being].

The author discusses some relationships between work situation (defined by contents, work load, and conditions of coping with stress) and the following variables: satisfaction with work, self-reported psychosomatic symptoms, alcohol consumption, and smoking. The analysis is based on interview data of 450 men aged 35 to 50.

Adult↗
PubMed1981

Pleural plaques and cigarette smoking in asbestos workers.

In a survey of 45 men aged 40 or over who had worked five years or more in an asbestos manufacturing plant, the prevalence of pleural plaques was studied with respect to age, duration of asbestos exposure, estimated cumulative asbestos dose, and smoking habit. Plaques were found in 38 to 53% of the men, depending on the interpretation of the chest film reader. Cigarette habit appeared to be the most important factor; the prevalence was lowest in non-smokers, intermediate in current smokers, and particularly high in exsmokers. There was some confounding of this relationship by estimated cumulative asbestos dose but such confounding did not seem to be sufficient to explain fully the relationship between the prevalence of plaques and smoking habit. Both factors must be considered in studies of the risk of pleural plaques in asbestos workers.

Adult↗
PubMed1980

[Endoscopic-diagnostic problems in malignant lymphoma of the upper intestinal tract].

A retrospective analysis of 79 patients with malignant lymphoma (ML) of the upper gastrointestinal tract in a series of 842 endoscopically verified malignant tumours is presented. There was a significant difference between carcinomas and ML: in the latter, macrosopic diagnosis was correct in more than 90%, while histologic evaluation of forceps biopsies was false negative in 23.2%. Guided brush cytology provided an unexpected gain of information in 35%. Gastroscopy should be performed even in symptomfree patients with ML. Errors of histologic evaluation can be avoided by wire loop biopsy. Extragastric involvement of ML was successfully demonstrated in 93% by 67-gallium scanning.

Biopsy↗
PubMed1980

[Clinical usefulness of 67 gallium scintigraphy in malignant lymphoma].

The results of 67-gallium scanning in 644 patients with histological confirmation of diagnosis are presented. 67-Ga uptake was recorded in 93.3% of 312 malignant and in 85.8% of 332 benign conditions. In 89.4% 67-Ga was successful in distinguishing between malignant and benign disorders. In 58 of 62 lesions due to malignant lymphoma 67-Ga uptake was seen. 67-Ga scanning is an indispensable tool for early diagnosis of hepatoma (n = 80) and an important non-invasive staging procedure for lymphoma patients which complements exploratory laparotomy.

Diagnosis, Differential↗
PubMed1980

The cigarette factor in lung cancer due to chloromethyl ethers.

In a prospective study of 51 men who had moderate to heavy cumulative exposure to chloromethyl ethers, 11 developed lung cancer in a ten-year perod. The risk was higher in men who were not smoking cigarettes at the start of observation than in those who were. This difference was even more impressive when examined in relation to the risks of lung cancer by smoking habit in the general population. The data suggest that continued cigarette smoking entailed a factor which partially inhibited the carcinogenic effect of chloromethyl ethers.

Adult↗
PubMed1980

The prognosis of lung cancer originating as an infiltrate. Data from the Philadelphia Pulmonary Neoplasm Research Project.

In a periodic screening study of 6,027 older men, 121 developed lung cancer during the 10 yr of observation. The over-all 5-yr survival rate was 8%, but when the 121 men were subdivided according to the initial radiographic appearance of cancer, a group of 23 with ill-defined peripheral lesions that we labeled "infiltrates" had the best prognosis over the first 5 yr of follow-up. This advantage tended to disappear thereafter. The men whose tumors originated as infiltrates also had the highest resection rate and were detected most frequently within 7.5 months of a negative film. The infiltrates tended to be smaller than the well-defined peripheral tumors that we designated round lesions. In 8 of 13 instances with radiographic follow-up, the infiltrates assumed the appearance of round lesions or irregular masses. These observations suggested that the infiltrate is often a biologically earlier lesion than other radiographic forms of lung cancer.

Humans↗