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Biomedical subjects

W Wagner

Publications and source records attributed to W Wagner.

At least 289 records · Page 16Linked to original sources
PubMed1981

A new objective criterion for determining, noninvasively, the healing potential of an ischemic ulcer.

Peripheral vascular perfusion studies using intravenously administered thallium-201 were performed on 13 patients suffering from ischemic ulcer of the lower extremities. Scintillation camera views and point counting over the lesion and adjacent region were utilized to define qualitatively and quantitatively the relative hyperemia of the lesion. The preliminary findings demonstrate that when the relative hyperemia was equal to or greater than 1.5, 100% (seven of seven) went on to heal their ulcer with conservative management. Of those without this degree of hyperemia, 83% (five of six) will require amputation. Based on this limited series, noninvasive assessment of the relative hyperemia of an ischemic ulcer using thallium-201 is a new, useful, and objective indicator of the healing potential of a so-called ischemic ulcer.

Amputation, Surgical↗
PubMed1980

Methods of intermittent positive pressure breathing.

Inspiratory capacity (IC) was evaluated in 60 patients during the following four respiratory maneuvers: (1) coached unassisted inspiration; (2) inspiratory positive-pressure breathing (IPPB) at 15 cm H2O with the patient passively inspiring; (3) IPPB at 15 cm H2O with the patient coached to actively inspire; and (4) IPPB at a peak pressure adjusted according to the judgment of the respiratory therapist, with the patient coached to actively inspire. The IC attained with these maneuvers were, respectively, as follows: (1) 1.29 +/- 0.75 L; (2) 1.13 +/- 0.52 L; (3) 1.77 +/- 0.11 L; and (4) 2.27 +/- 0.11 L (mean +/- SE). The peak ventilator pressure for maneuver 4 averaged 30 +/- 7 cm H2O (mean +/- SD), and no patient experienced harmful side effects from these peak pressures. These data indicate that the method of treatment with IPPB has profound effects upon the degree of pulmonary expansion. All research on therapy with IPPB should be carefully controlled for the method of administering IPPB, and the volumes obtained during the treatment should be carefully documented before general conclusions are drawn concerning the effects of IPPB on morbidity. For the present, we suggest that IPPB, when administered clinically, be given as described in method 4.

Adult↗
PubMed1980

Properties of a combined sensor for dynamic measurement of oxygen in simulated respiration.

A combined sensor supplying momentary values of respiratory functions (flow, PO2, and temperature) for calculation of oxygen intake is tested in simulated respiration. Signal conditioning reduces the errors caused by the influence of CO2 on the sensitivity of the oxygen electrode, by the electrode response and time lag. Oxygen intake of 0.38 and 1.49 liters/min simulated by injection of N2 into the respiration pump (10--40 cycles/min) is analyzed by means of the combined sensor (signals conditioned; time constant about 40 msec) and calculated with a mean error of about -10%. The error rises with increase of the time constant as well as the respiration frequence.

Carbon Dioxide↗
PubMed1980

[Regeneration in bony defects after implantation of resorbable calcium phosphate ceramics. A comparative clinical study].

After experimental demonstration of the excellent tissue tolerance with ceramics-bone contact without connective tissue in animals and because of the good resorbability of tri-calcium phosphate ceramics (TPC), TPC ceramics was used in a clinical study to fill the bony defects resulting from apicectomies and cystectomies. The patients were controlled for a period of up to six months. After an initially normal healing phase, an unusually high rate of late complications with fistula formation and rejection of the TPC ceramics was observed around the tenth postoperative week. Possible causes for these late complications were discussed.

Apicoectomy↗
PubMed1980

[Urothelial tumors of the upper urinary tract. Experience with 85 cases].

85 patients with uroepithelial tumors of the upper urinary tract were treated between 1960 and 1975. A retrospective study was done on 71 patients. A follow-up examination was done on 23 patients. The average age was 59 years, lower than in most other series. Macrohaematuria was the most frequent symptom in 85,9% of the cases. Patients complained of pain in 57,7%. The average duration of symptoms was 8 months. 5 years survival after nephroureterectomy was 33% (15/45), almost the same as after nephrectomy 35% (7/20). The recurrence rate however was 45% (9/20) after nephrectomy and 11,8% (6/51) after nephroureterectomy. Nephroureterectomy should be the treatment of choice of uroepithelial tumors of the upper urinary tract. The indications for simple nephrectomy and conservative surgical procedures are discussed.

Adult↗