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Biomedical subjects

W L Qiu

Publications and source records attributed to W L Qiu.

At least 73 records · Page 4Linked to original sources

[Experiment study on biological and immunological characteristics of modified DNL of oral squamous cell carcinoma with TNF-alpha gene]

Growing characteristic of gene-transduced and nontransduced DNL in medium of containing rIL-2 was compared,and growing characteristic of gene-transduced DNL in medium of non containing rIL-2 was analyzed.DNA index (DI),cell cycle and immunologic phenotypes of gene-transduced and nontransduced DNL were analyzed with FACS.The results revealed interfered with growth,DL,cell cycle and immunologic phenotypes of DNL,and gene-transduced DNL couldn't growing infinitely.

Journal Article↗

Experimental ligation versus embolization of the external carotid artery: a comparative hemodynamics study.

Patterns of collateral vascularization were investigated by SEM evaluation of microvascular corrosion casts following either ligation or embolization of the external carotid artery in the rabbit. Results indicated that rich collateral channels were established soon after ligation of this artery, and blood supply to the lesional area was never cut off. In contrast, embolization effectively obstructed blood supply by reducing collateral branches. We concluded that for purposes of controlling blood loss, it is more helpful to employ external carotid embolization rather than ligation for oral maxillofacial lesions with a rich blood supply.

Animals↗

[The diagnosis value of malignant tumors in the Oral and Maxillofacial region using healthy person's free radical of hair]

Electron spin Resonance(ESR) was used to determine the free radical of hair from 324 cases.These cases included 185 healthy persons,33 benign tumor patients,84 malignant cases and 22 oral mucosa disease cases.The determined results were controlled with pathologic diagnosis to analyse the accordance. The result showed the positive rates of above mentioned cases were 5.9%,6.1%,84.52%and 9.1% respectively.The significant differences were observed when comparing the results of malignant cases with healthy person and benign tumor cases with healthy person and benign tumor cases(P<0.01).The ESR saturation power points of some malignant cases rose to above border-line(>10.0mW) after treatment.These results indicated using ESR to diagnosis early malignant cases and follow treatment effect possess certain clinical value.

Journal Article↗

[Evaluation of effect of the surgical therapy for the oral and maxillofacial arteriovenous malformations.].

Since 1986,the diagnosis and treatment of 23 patients with oral and maxillofacial malformations have been prospectively studied.We have put forward a planned managing programme including the selective external carotid arterograph,accessory preoperatively arterial embolization,radical resection of lesion and immediate reconstruction of defect after primary resection for oral and maxillofacial arteriovenous malformations.We have got a satisfactory clinical effect.All these patients were followed up.The longest follow-up time was 6 years and 10 months.The average follow-up time was 4 years and 3 months.The rate of recurrence was only 4.3%(1/23).In this paper,we compared the different effect between the accessory arterial embolization and the arterial ligation.The result of comparing between two methods was that the arterial embolzation was superior to the arterial ligation.

English Abstract↗

[The Chinese traditional treatment with "ShengYang" prescription as a post-operative auxiliary method using on the oral squamous cells carcinoma patients.].

This paper observed the clinic investigation.Which prove the relationship among the Chinese dialectical fur condition pulse condition,dialectical divided into types and survival time,immunity function before and after therapy,which will provide scientific basis and new train of thinking for recovery of stomatological carcinoma patient following operation.These patients according to dialectical type.were divided into type of feeble kidney and type of mixed excess and deficiency syndrome that the survive time compare with control group through treat by statistics,were P<0.05.The positive cases of immunity response of administration group were more increased than control group, the rate was 22.2%,maintenance and decrease rate were 7.5% and 14.6% compare with control group,with multiple factor computer analysis in two groups.There is some evidence that the traditional Chinese prescription of "ShengYang" treat in tumor patients with the type of feeble kidney and type of mixed excess an deficiency syndrome were remarkably regulate the immunity function and promote the action of anti tumor.For recovery therapy after tumor operation which reach a fairly action.

English Abstract↗

[Effect of Chinese traditional prescription "Shen Yang" on the immune function of oral squamous cells carcinoma patients.].

This report tries to compare the immunologic function of being take the Chinese medicine "Fu-Fang Shen Yang" or placebo C which is based on randomized clinical trials after operation for 238 cases of oral squamous cancer.DNCB test is for observable index.The results as follows:DNCB position rate of 1 "Shen Yang" group is significantly increased to compare with the placebo C group,after 3m(P<0.01) 6m (P<0.001).Two groups are significantly increased after one year.This suggestion that "Fu-Fang Shen Yang" can enhance immunologic function after operation fro oral squamous cells carcinoma patients.

English Abstract↗

Cephalometric studies on the upper airway space in normal Chinese.

A detailed cephalometric analysis of the soft and hard tissues of the upper airway was conducted with lateral cephalographs from 116 normal Chinese, aged between 18 and 25 years. Normal values and deviation range were preliminarily established for the size of the tongue, soft palate, nasopharynx, oropharynx, and hypopharynx, and for the relative position of the hyoid bone and vallecula in both sexes. Statistical findings showed that there were significant differences between the sexes. Significant relationships (P < 0.001) were observed 1) between the hypopharyngeal depth and the position of the hyoid bone and the vallecula, in which the horizontal position of vallecula appears to be the best predictor of the hypopharyngeal depth, as confirmed by the multiple regression equation; 2) between the upper airway depths at four different levels; and 3) between the naso-oropharyngeal area and tongue, soft palate, and oral area. The present data can be used to investigate further the upper airway in abnormal states.

Adolescent↗

[One-stage surgical procedure of adult cleft palate with dentofacial deformity]

2 cases with primary adult cleft palate combining severe dentofacial deformities were undergone one-stage procedure of modified Le Fort I segmental osteotomy and Furlow's double reserving Z plasty,and with with satisfactory clinical effectiveness.Follow-up results show that the one-stage procedure is not only reducing treatment time and period,but also correcting velopharyngeal function.

Journal Article↗

[The measurement of EMG and deglutition pressure after glossal reconstruction]

Newly designed computer system (SAMP-EMG) was utilized,to measure the myoelectric signal in each region of the 100ms integral values and do the power spectral analysis in 10 normal people and 20 patients.At the same time,the pressure of deglutition was determined with the liquid pressure conducting electronic device.The results were :1.In normal EMG,the myoelectric power in anterior tongue is the highest,that in the margin of the tongue is the second,that in dorsum central area is the lowerest;2.There in no effective myoelectric signal detected in any kind flap;3.Normal swallowing pressure is 21.1+/-5.7kPa,the average value of FA is 10.3kPa,PM is 10.8,GC is 14.6.

Journal Article↗

[A contour and mineral content comparison of vascularized and non-vascularized bone grafts]

This study made a comparison between vascularized bone graft (VBG) and non-vascularized bone graft (NVBG) in mandible of canine by using electron computer to assess the contour of grafted bone and measuring the mineral contents. On the 3rd, 5 th, 7 th, 15 th postoperative day, the contour of VBG and NVBG were similar and all of them kept the original contour. On the 30 th,60th,90th,180th postoperative day, VBG remained the original contour, but the contour of NVBG became thicker obviously than that of VBG for the remained cortical bone(most of which was resorbed) were enveloped with a lot of new bone. The kind of resorption of NVBG cortical bone in our study was characterized by extensive resorption on the surface just like nibbling of silkworm, unlike "tunnel" described in the literatures. There were no statistically differences between mineral contents of VBG and that of NVBG.

Journal Article↗

[Clinical assessment of rehabilitation after radical surgery of tongue cancer.].

It is same important to consider both patient's own evaluation and the clinical examination.It is helpful to judge the state of the functional rehabilitation. We have followed up 128 cases of tongue cancer postoperatively,recieved 104 letters and checked up 87 patients in the clinic.It has been discovered:1.the female patients paid more attention to the speech and apperance,while the male to the eating;2.on the donor site of flaps,some patients complained of the numbness in the fingers and the obvious scars in the forearm flap,while the fracilis myocutaneous flap is a relatively good method;3.in the cases of 1/2 anterior glossal defect,the forearm flap is available;to that more than 2/3 defect of the tongue,we used the myocutaneous flaps which have great volume of tissue;4.it is necessary to concern the mobility of the essential factors effecting the functional rehabilitation.

English Abstract↗