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Biomedical subjects

W Kaiser

Publications and source records attributed to W Kaiser.

At least 127 records · Page 7Linked to original sources

[Experimental animal studies of the healing of burn wounds with the use of local antimicrobials and hyperbaric O2 therapy].

Standardized burns without experimental infection and such with infection by a constant number of bacteria of a fixed Pseudomonas-aeruginosa-strain were treated differently. Silver sulfadiazine- and Cefsulodin-cream, Polyvidon-iodine-ointment (PVP-Jod), and hyperbaric oxygen (OHP) were used to them. The courses of healing were checked by determination of the wound area daily. The best results showed the experimental uninfected untreated wounds. Wounds infected by Pseudomonas were healing most quickly by immediate and continuous application of hyperbaric oxygen. By silver sulfadiazine- and Cefsulodin-cream treated burns showed statistical significant better results than the control group. The courses of healing were significantly poorer in delayed application of OHP (only from the 8th day after the burn) or in case of therapy with PVP-iodine alone.

Administration, Topical↗

[Effects of hyperbaric oxygen on fresh burn wounds].

In an experimental study standardized third-degree burns were caused in guinea pigs. The animals were treated intermittently with hyperbaric oxygen for a period of five days starting immediately after injury. The healing process was recorded at frequent intervals using a photographic technique and planimetric determinations. In addition, the wounds were excised at predetermined intervals for the purpose of histological examination. Untreated animals demonstrated a considerable increase in wound area as compared to the initial lesion, while there was a tendency to reduced wound area in the treated animals. Histological studies revealed considerably less subcutaneous edema in tissue samples obtained from the treated animals than in specimens from the control group. The effect of hyperbaric oxygen on fresh burns is discussed on the basis of the experimental findings.

Animals↗

[Personal preparation of bicarbonate solutions--cost comparison and quality control].

Haemodialysis with bicarbonate dialysate is well established in the treatment of chronic renal failure. The costs of bicarbonate haemodialysis are higher than acetate haemodialysis. Commercially available bicarbonate solutions are sold from AS 129.- to AS 189.- per 8 litre canister (December 1987). The self-prepared solution contains 650 g bicarbonate (for AS 8.-) in 8 litres of deionized water. In 10 patients on regular dialysis treatment haemodialysis were performed with both commercially available and self-prepared solutions for a 3 week period. Blood and dialysate samples were obtained before and 10 minutes, 1 h, 2 h, 3 h and 4 h after starting haemodialysis. Osmolality, Na+, K+, Cl-, pO2, pCO2 and pH were measured in the dialysate and in the serum, as well as serum lactate levels. There were no significant differences and the biochemical changes were similar with both preparations. In our centre with about 4000 bicarbonate dialyses yearly, AS 500,000.- to AS 700,000.- could be saved by self preparation of the dialysate.

Bicarbonates↗

[History of the Halle Ars Medica Judaica. I. Dedication of the Gröbzig Synagogue Museum].

The inauguration of the reorganized Museum Synagogue Gröbzig gives rise to remind of the fascist race terror, the first phase of which is periodized for the years between 1933 and 1938. Documentations from the era further dating back make recognize already formerly preformed ways which initiated those events having reached their first culmination point with the excesses of 1938. Also in the Medical Faculty of Halle University these events left deep traces.

Germany↗

[200th anniversary of the Schola clinica Halensis].

The Schola clinica Halensis of the ending 18th century forms the succeeding institution of the Collegium clinicum Halense founded in 1717. Under the leadership of Johann Christian Reil this institution directed to the imparting of practice-orientated knowledge and skill reaches a considerable level. For the first time the contours of a teaching hospital connected with a university are outlined. Shortly after the turn of the century to the clinical and policlinical modalities of training a hospital laboratory is added; bedside chemistry by this means is first consolidated.

Germany↗

[Transient extra-osseous increase of isotope activity in the bone scintigram in acetolyt-induced hypercalcemia].

A 66 year-old man with chronic renal failure developed hypercalcaemia during acetolyte medication. A technetium-99m phosphate bone scan at this time showed extraosseous isotope uptake in the stomach, which disappeared 2 weeks later after normalisation of the serum calcium level. This phenomenon can be interpreted as transient metatastic calcification during hypercalcaemia.

Aged↗

[Russia-Halle reciprocity in medicine in the 18th century. VI. Evaluation of a secular period].

During the 18th century about 40 medical men who declared Russia their native country took their academic degree in Halle. This number is nearly identical with a group of medical immigrants coming from Halle of circa the same size, most of them remaining in the chosen home. For circa 70 persons of these two groups of physicians a permanent activity is to be proved during this century. Their lives and work were described in this series of contributions devoted to the interrelations of Russia and Halle in medicine of the 18th century.

Foreign Medical Graduates↗

[Russia-Halle reciprocity in medicine of the 18th century. V. Halle graduates employed in Russia and their medical fields].

In the 18th century about 40 medical men of non-Russian descent graduated in Halle temporarily or permanently entered the Tsarist services. Their activities are to be proved in nearly all fields of medicine. They occupied positions as court-physicians and military surgeons, worked in hospitals or as free practitioners. Some of them occupied important positions in research and education at the Academy of Petersburg and the University of Moscow.

Germany↗

[Russia and Halle reciprocity in medicine of the 18th century. Correspondence, scientific communication and reception].

In the history of the interrelations of Halle and Russia in medicine during the 18th century Francke's Foundations, the Faculty of Medicine and the Academia Naturae Curiosorum are important institutions. The correspondence of these three institutions with the partners in Russia became remarkable for the scientific communication and reception. The activities of the working teams which were embedded in these authoritative bodies were scarcely inferior in importance to the centres of enlightenment of that time working in other towns (for instance in Leipzig). In the field of medicine Halle occupied a leading position for the early knowledge about Russia.

Germany↗

[Successful outcome of high-risk pregnancy within 1 year following kidney transplantation with cyclosporin as the immunosuppressive agent].

A 41-year-old female patient with analgesic nephropathy became pregnant 13 weeks after successful renal transplantation using cyclosporin as an immunosuppressant. Because of rhesus incompatibility of the mother this was thought to be a high risk pregnancy. In spite of the increased risk of CyA-induced nephrotoxicity in this early phase after transplantation, the patient showed the same physiological renal changes during pregnancy as healthy control patients: a 24% increase in creatinine clearance and an increase in protein excretion of only 41 mg/day. To maintain a CyA-blood concentration of 200-600 ng/ml throughout the pregnancy the CyA dose had to be increased from 380 to 550 mg daily or from 6.9 to 8.3 mg/kg/day (20%). This increase in CyA requirement may indicate additional metabolism of CyA by the fetal liver.

Adult↗

[Russia-Hall relations in medicine of the 18th century. III. Halle physicians as research travelers and members of expeditions].

In the history of Russian expeditions in the 18th century several physicians and natural scientists who were educated in Halle and temporarily working, respectively, at the university of the city on river Saale occupy a respectable position. Names such as Buxbaum, Messerschmid, Stoeller, Lerche and Pallas are mentioned with high respect up to the present time. The results of their investigations in Sibiria, in Caucasia and in Persia are regarded as pioneer achievements which became the prerequisite for the investigations of the 19th century.

Expeditions↗

[Russia-Halle interrelations in medicine of the 18th century. II. Halle medical delegations in Czar Peter's Russia and later].

In the 18th century for the purpose of amelioration of the medical care by the authorities responsible for the medicinal organization in Russia aimed methods of delegation were brought about. Requests of such kind were sent to the medical faculties of renowned universities. In such requests the University of Halle played a significant role. For the 18th century more than 40 candidates for a Halle doctorate can be authenticated who took Russian services for a certain time or for ever and there obtained important positions during their stay.

Germany↗

[Russia-Halle interaction in medicine of the 18th century. I: The medical organizers Johann Deodat Blumentrost (1676-1756) and Laurentius Blumentrost (1692-1755)].

In the Russian medicinal and scientific organization of the early 18th century decisively promoted by Czar Peter I such personages as the physicians Johann Deodat Blumentrost and Laurentius Blumentrost have obtained important key positions. Last not least their work was characterized by inspirations which they received at the university of Halle the destination of many of their compartriots in the Petrine and Postpetrine era. At the Petersburg Academy of Sciences which began its work in 1725 Laurentius Blumentrost was its first president.

Germany↗

Projection areas and branching patterns of the tympanal receptor cells in migratory locusts, Locusta migratoria and Schistocerca gregaria.

In Locusta migratoria and Schistocerca gregaria, the projection areas and branching patterns of the tympanal receptor cells in the thoracic ganglia were revealed. Four auditory neuropiles can be distinguished on each side of the ventral cord, always located in the anterior part of the ring tract in each neuromere (two in the meta-, one in the meso-, and one in the prothoracic ganglion). Some of the receptor fibres ascend to the suboesophageal ganglion. There are distinct subdivisions within the auditory, frontal metathoracic and mesothoracic neuropiles. The arrangement of the terminal arborisations of the four types of tympanal receptor cells according to their different frequency-intensity responses is somatotopic and similar in the two ganglia. Here the receptor cells of type-1 form a restricted lateroventral arborisation. Cells of type-4 occupy the caudal part with a dorsorostral extension. Cells of type-2 and -3 arborise in a subdivision between both. Most of the stained low-frequency receptors (type-1, -2, and -3) terminate either in the metathoracic or, predominantly, in the mesothoracic ganglion. In contrast, the high-frequency cells (type-4) ascend to the prothoracic ganglion. The receptor fibres of the different types of receptor cells differ in diameter.

Animals↗