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Biomedical subjects

W Kaiser

Publications and source records attributed to W Kaiser.

At least 109 records · Page 6Linked to original sources
PubMed1989

[Halle physicians as historical witnesses and specialty chronologists. I. The autobiography of the wound physician Johann Dietz (1665-1738)].

The beginnings of the autobiography and autoergography written by physicians are to be placed for the 16th and 17th century. An early example for this genre of literature which is always actual but in its valency also disputed is the self-evidence of the Halle surgeon Johann Dietz. Into the descriptions of his professional life many details of the events of his era were included. In his description chronicles of the speciality and witness of the time united themselves in a report which remained worth reading up to the present time.

General Surgery↗
PubMed1989

[History of the Halle Ars medica Judaica. V. Scientific achievements and medical publications of 2 centuries].

A medico-scientific journalism of Jewish origin which became increasedly recognizable on the German territory in the second half of the 17th century was at first based on the activities of Spanish-Portuguese exiles. Beginning with the 18th century at first the inaugural papers, but then also the publications of renowned Jewish physicians determined the profile of this literary group. The access to academic teaching professions becoming possible in the 19th century developed concentration points of research engagement, which in this place shall be indicated at the instance of the Medical Faculty of Halle University.

Education, Medical↗
PubMed1989

[History of the Halle Ars medica Judaica. IV. Development from the middle of the 19th century to the end of the Weimar Republic].

The possibilities of an academic career of Jewish physicians were alleviated by the legalities of the second half of the 19th century, however, up to 1918 in many places restrictive statutes in higher education considerably confined a career as professor in ordinary of specialists of Jewish belief. The conditions at Halle university reflect this situation. A complete equalization beginning after 1918 only at some points of scientific concentration led to a recognizable increase of the Jewish-German members in the teaching staff. But already in this phase on the basis of a quickly spreading racial ideology an increasingly appreciable vulgar antisemitism developed.

Education, Medical↗
PubMed1989

[History of the Halle Ars medica Judaica. III. The path to academic equality].

After the repeal of the special decisions for Jewish candidates for a doctorate which was done in 1784 it lasted still more than 60 years, before a far-reaching equality of status became reality also with regard to possibilities of a university career. In 1847 this phase of development is marked by the official licence of Jews to academic teachership. It is a partial complex within a general process of emancipation which was quite differently practised in the German territorial states.

Education, Medical↗
PubMed1989

[Calcium-free hemodialysis--value in therapy of hypercalcemic crisis].

If conservative treatment of hypercalcemic crises is ineffective, low calcium bath or zero calcium bath hemodialysis represent good alternatives. We report 5 patients (from 54 to 82 years old) treated with calcium free acetate hemodialysis because of hypercalcemic crises due to breast cancer with bone metastases, thiazids' medication and immobilisation, liver cirrhosis, hepatocellular carcinoma and hyperparathyroidism. By 3 hours' therapy calcium concentration could be reduced from a mean value of 3.74 mmol/l (3.13-4.46) to 2.47 mmol/l (1.38-3.12). In 3 cases rapid clinical improvement was achieved and in 4 cases the subsequent conservative therapy was sufficient to maintain serum calcium levels within reference range. In accordance to other investigators we consider hemodialysis as an effective method of low risk in hypercalcemic crises. Calcium rebound may occur in patients with hyperparathyrodism.

Aged↗
PubMed1989

[The history of the Halle Ars medica Judaica. II. The beginnings of Jewish medical education].

In the 18th century the University of Halle became the central point of approach of Jewish students of medicine. To the end of the century more than 60 doctor's diplomas were given to Jewish candidates by the Faculty of Medicine of Halle University. The decisions of restriction which at the beginning were valid also here were gradually loosened. In 1784 the examination process was assimilated to that one of the Christian graduates.

Education, Medical↗
PubMed1989

Quantification of myocardial ischemia and infarction with single photon emission computed tomography.

To evaluate the feasibility of 201Tl single photon emission computed tomography (SPECT) for quantitative detection of myocardial infarction and ischemia, scintigraphic studies were related to angiographic findings. In study A infarct sizes with SPECT were compared with the angiographic infarct sizes of 30 patients. A linear correlation was found for the % infarct of the left ventricular circumference between both methods (r = 0.73; P less than 0.001; mean infarct size 20.7% +/- 10.5% (angio) vs 19.8% +/- 12.9% (SPECT), mean +/- SD). Furthermore, a significant inverse correlation between scintigraphic infarct size and left ventricular ejection fraction (r = -0.87, P less than 0.001) was obtained. In study B exercise/rest 201Tl SPECT was used for quantification of myocardial ischemia. Forty-three patients underwent both stress 201Tl SPECT and biplane exercise left ventriculography. Ischemia was expressed as % defect size of the left ventricular circumference. Sensitivity and specificity for detection of ischemia were 96% and 100% respectively with stress SPECT. Extent of myocardial ischemia correlated significantly with both methods (r = 0.63; SPECT defect = 1.0 angiographic ischemia +2%; P less than 0.001). The regression followed the line of identity and the mean sizes of ischemia were identical (SPECT 12.2 +/- 7.6% vs 14.6 +/- 12.4% ventriculography, mean +/- SD) demonstrating the agreement of both methods. However, there was some intraindividual variance between the scintigraphic and the angiographic study. The sensitivity and specificity in single regions with SPECT were lower compared to the global test results.(ABSTRACT TRUNCATED AT 250 WORDS)

Angiography↗
PubMed1989

Calcium free hemodialysis: an effective therapy in hypercalcemic crisis--report of 4 cases.

Hypercalcemic crisis represents a medical emergency. If conservative treatment is ineffective, low calcium bath or zero calcium bath hemodialysis are good alternatives. We report 4 patients treated with calcium free acetate hemodialysis because of hypercalcemic crisis due to breast cancer, hepatocellular carcinoma, cirrhosis of the liver and immobilisation with hydrochlorothiazids' medication. Following 3 h of hemodialysis, serum calcium concentrations fell from a mean value of 3.96 (range 3.53-4.46) mmol/l to 2.71 (2.28-3.12) mmol/l. In 2 patients rapid clinical improvement was achieved and in one oliguric patient diuresis started spontaneously during hemodialysis. One patient died from gram-negative sepsis. In 3 cases the subsequent conservative treatment was sufficient to maintain serum calcium levels within the normal range. Together with the previously reported cases (5 patients treated by hemodialysis with low dialysate calcium and 3 patients by hemodialysis with calcium free dialysate) our experience indicates that hemodialysis is an effective and safe therapy for hypercalcemic crisis.

Aged↗
PubMed1989

[Not Available].

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Expeditions↗
PubMed1989

[Imaging of intra-cardiac thrombi with indium 111 scintigraphy].

Intracardiac thrombi can be localized and quantified by Indium-111-labelling of thrombocytes with a high sensitivity and specificity. The scintigraphic procedure has a complementary evidence to echocardiography. Scintigraphy shows activity and age of thrombosis, whereas echocardiography seems to be superior in determination of mass and localization. In older thrombi scintigraphy fails because of organisation and endothelialization of the thrombus surface. For the reason of determination of the age of an intraventricular thrombus this method might have an increasing acceptance.

Aged↗
PubMed1989

[Lung thallium uptake for non-invasive assessment of increased pulmonary pressure in mitral valve stenosis].

30 patients (24 females, 5 males) with angiographically proven mitral stenosis as well as 10 healthy controls were investigated by wedge catheterism and thallium-201-scintigraphy to calculate the heart-lung quotient (HLQ) of the isotope. All patients with mitral stenosis could be discriminated from controls by a pathological increase of isotope concentration in the lungs. 4 groups could be subdivided: the 1st group consisted of 21% of the patients with normal pulmonary artery pressure of x = 13.06 mm Hg and a normal HLQ less than 1.1. The 2nd group of 39% of the patients showed passive pulmonary hypertension with a PAm of x = 27.57 mm Hg and HLQ between 1.1 and 1.4 A 3rd group showed PAm of 36.76 mm Hg with reactive pulmonary hypertension and a HLQ between 1.4 and 1.6. The last group showed pulmonary hypertension of x = 45 mm Hg PAm and a HLQ of greater than 1.6. Scintigraphy alone allowed classification of the patients, so the value of this method is proven for pre- and postoperative strategy.

Exercise Test↗