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Biomedical subjects

W Becker

Publications and source records attributed to W Becker.

At least 541 records · Page 30Linked to original sources
PubMed1979

[Lithium balance in mania].

Lithium balance studies were performed in 19 patients suffering from mania and 6 patients suffering from depression. The following results were obtained: (1) The mean daily requirement for lithium in the manic patients was 52 mM, in those with depression 30 mM (additional requirement in manic patients 73%). (2) Renal elimination of lithium, after optimal blood lithium levels had been reached, was 76% in mania and 97% in depression (retention in manic patients 21%). (3) In mania there was an unchanged lithium half-life time (12-13.5 h). (4) In mania and depression no significant differences in lithium and creatinine clearance were noted. (5) Standard diet or unrestricted sodium chloride administration did not significantly influence the lithium requirement or lithium retention. After exclusion of a renal or dietetic cause for increased lithium requirement or retention during mania, the existence of a 'lithium pool' dependent on the presence of a manic psychosis seems probable. As a result of this, somatic influences on endogenous psychosis have to be taken into account.

Adolescent↗
PubMed1978

Hereditary atrial septal defect. Update of a large kindred.

A large pedigree wherein members are predisposed to atrial septal defect (ASD) and associated cardiovascular anomalies has been studied. There were ten direct line relatives with ASD verified by cardiac catheterization and/or surgery and in one case by reliable medical history. The pedigree shows vertical transmission of ASD through four generations. Estimates of the genetic segregation ratio were near 50%, indicating that predisposition to ASD among family members was due to a deleterious autosomal dominant gene. Family members have also manifested other congenital heart anomalies, consistent with pleiotropic effects of the putative gene. Electrocardiograms in six ASD patients revealed an absence of prolonged P-R interval. In the light of prior studies showing prolonged P-R interval in familial ASD, we suggest the existence of at least two distinct hereditary varieties of ASD, one with and one without a prolonged P-R interval.

Adolescent↗
PubMed1978

The effect of phentolamine on intra-Hisian conduction.

A His bundle electrogram was obtained in a 70 year old male with syncopal episodes. A split bundle of His deflection was recorded. After the intravenous administration of phentolamine, a marked shortening of the H-H' interval was observed. This signifies an improvement in conduction at the bundle of His level.

Action Potentials↗
PubMed1978

Premature hair graying: a probable coronary risk factor.

Hypertension, diabetes mellitus, hypercholesterolemia, and smoking are known coronary risk factors. It has been our impression that premature graying of the hair also predisposes individuals to myocardial infarctions. To test this hypothesis, we evaluated all of the patients under the age of 50 who were admitted to the coronary care unit between 1974 and 1976 with a proven diagnosis of a myocardial infarction. There were 50 patients. Thirty-eight did not have premature graying. Twelve of the male patients (24%) had virtual total graying of the hair which made them appear older than their stated age. The graying in these patients started on the average at 29 years. Five of these patients state that other family members had premature hair graying. The incidence of diabetes, hypertension, and smoking was similar in those with and without premature hair graying. This preliminary study suggests that premature graying of the hair is associated with premature cardiovascular disease. It should probably be regarded as a coronary risk factor and used to identify patients at increased risk.

Adult↗
PubMed1978

[Medicolegal consequences of a recurrent nerve palsy after thyroidectomy. (Including a contribution on the function of the medical expert) (author's transl)].

An Ear, Nose and Throat surgeon was accused because a unilateral recurrent nerve palsy arose after a thyroid operation. The patient was making unreasonable financial claims. The otolaryngologist who provided the medicolegal report recognised that the whole personality of the plaintiff should be assessed by an additional neuro-psychiatric examination. The reporting specialist concluded that she was suffering from an involutional depression and that her symptoms and complaints against the surgeon were attributable to her depression and not to the operation. The facts of the litigation, medicolegal details and judgement rejecting the indictment are presented. The possibility of a reverse "malpractice suit" is discussed by the authors.

Consumer Behavior↗
PubMed1978

[The problems of simultaneous tympanoplasty and adeno- tonsillectomy (author's transl)].

The effect of adento-tonsillectomy on tube function and middle-ear ventilation was measured by tympanometry and manometry. It was found, that after adenotomy considerable negative pressure values may develop in the middle ear. In about one third of all cases five to six days after operation the tube function was not yet normal again. After tonsillectomy alone only a few of the operated children has slight negative pressure values. Adenotomy and tympanoplasty should not be achieved simultaneously.

Adenoidectomy↗