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Biomedical subjects

W Becker

Publications and source records attributed to W Becker.

At least 523 records · Page 29Linked to original sources
PubMed1979

[Dyschondroplasia with glioma of the brain. Third histologically verified case (author's transl)].

Dyschondroplasia is a mesodermal dysplasia with typical skeletal malformations of varying extent and severity. The combination with other malformations has led to numerous disease entities (Maffucci's syndrome, M. Kast, M. Ollier) that should be regarded as different forms of the same syndrome. The importance of the rare disease lies in the high risk of sacomatous transformation of the skeletal lesions and furthermore in an increased risk of development of other tumours. Involvement of the central nervous system is possible through lesions of the bones of the skull or through primary intracranial tumours. The present report concerns a patient with dyschondroplasia complicated by the occurrence of a cerebral glioma and is the third reported case verifed by biopsy.

Adult↗
PubMed1979

Electrophysiologic properties of coffee in man.

There is no information on the effects of coffee on the human conduction system. His bundle electrograms were obtained in 12 patients before and 20 minutes after the ingestion of coffee containing 150 mg caffeine. Antegrade and retrograde refractory periods were obtained with the extrastimulus method. The effective and functional refractory period of the atrioventricular node decreased after coffee ingestion. This improvement in conduction is probably mediated by a release of catecholamines.

Adult↗
PubMed1979

Experimental autonomic neuropathy: ultrastructure and immunohistochemical study of a disorder of reflex vasomotor function.

Vasomotor function in ear vessels of rabbits was tested in animals with experimental autonomic neuropathy (EAUN), experimental allergic neuritis (EAN), and controls. Reflex vasodilatation was impaired in animals with EAUN but not in EAN or control rabbits. Ultrastructural examination of paravertebral sympathetic chain, perivascular nerves, and perivascular tissue showed similar changes in all animals differing in degree only. Occasional lymphocytes were seen in paravertebral chains of controls but large numbers of lymphocytes and macrophages occurred in EAUN and EAN. No active destruction of myelinated or unmyelinated fibers could be seen. Perivascular nerves showed similar cellular infiltrates and basophils were found in perivascular spaces of ear vessels which were most abundant in animals with EAUN. Fibre-size spectra analysis of unmyelinated fibres in the paravertebral sympathetic chain showed a shift to the left suggesting regeneration of unmyelinated axons in both EAN and EAUN. No specific immunofluorescence against neuronal components could be demonstrated in sensitized animals. It is concluded that the functional disturbance of reflex vasomotion in EAUN is not accompanied by specific ultrastructural lesions nor could neuronal components be immunologically implicated in the disorder. Regeneration of unmyelinated axons and recovery of function after some weeks together with abundance of basophils in perivascular tissue of sensitized animals, suggests that a localized inflammation may have occurred, the basophils interfacing between foreign antigens, the serum cascade systems, and other inflammatory cells. The usefulness of EAUN as a model for acute pandysautonomia in man remains to be determined.

Animals↗
PubMed1979

Alterations of the free amino acid content in the hemolymph of Biomphalaria glabrata (Pulmonata) in starvation and after infection with Schistosoma mansoni (Trematoda).

1. Analysing the free amino acid content of the hemolymph of normally fed, starved and schistosome-infected Biomphalaria glabrata we identified 22 amino acids and amines, respectively. 2. In comparison with normally fed snails the free amino acid content of starved and infected snails was significantly reduced. 3. However, only slight differences between the ornithine and citrulline content occurred in the three test groups.

Amino Acids↗
PubMed1979

Stereotactic localization of breast lesions.

The author describes a method of localizing nonpalpable breast lesions by transferring measurements from craniocaudal- and lateral-view radiographs to the breast itself in order to determine needle placement. In the more than 100 attempted cases, the lesion has been specifically localized, usually within 1 cm of the needle tip. Percutaneous biopsy can be carried out with the first needle used as a guide wire for the biopsy needle.

Aged↗
PubMed1979

Untreated periodontal disease: a longitudinal study.

Thirty diagnosed but untreated patients with moderate to advanced periodontal disease were examined a minimum of two times. The examination time intervals ranged between 18 and 115 months. 2. A total of 83 teeth were lost between examinations. 3. Excluding a patient who lost 25 teeth, a total of 58 teeth were lost. The adjusted tooth loss was 0.61 tooth per patient per year (or 0.36 with the elimination of 22 "hopeless" teeth). 4. The mandibular and maxillary molars had the greatest percentage of tooth loss between examinations. 5. All 29 patients completing the study had progessive increases in pocket depth during their time in the study. Increases in the mean annual pocket depths per tooth per patient varied from 0.24 millimeter per year to 2.46 millimeters per year. 6. The disto-lingual and mesio-lingual interproximal surfaces had the greatest increases in surface pocket depths. The lingual and buccal surfaces had the smallest increases in pocket depth. 7. The rate of increase in pocket depths was less in patients over 44 years of age. 8. The teeth which were lost had greater initial pocket depths and mobility scores than those which were present at both examinations. 9. There was no correlation between increases in pocket depth and changes in mobility. 10. All 29 patients showed radiographic evidence of progressive bone resorption between examinations. The posterior segments of the mouth had the largest amounts of bone loss between the first and last examinations.

Adult↗
PubMed1979

[Panel discussion: problems of the specialist's duty to inform the patient (author's transl)].

The obligation of the physician to inform the patient--which he has to prove in case of a suit--is based on the patient's right of selfdetermination. This self-decision information was subject of the panel discussion. Not discussed in detail were the information concerning diagnosis and prognosis, and the instruction of the patient regarding his conduct postoperatively and during medical treatment. Not considered was the so-called malpractice and negligence respectively. Medical liability suits are increasing for various reasons and are frequently directed at a failure to inform the patient because the patient is often unable to prove a negligence of the physician ("surrogate liability"). The dimension of the duty of disclosure (complete information--no information at all) is discussed in general and with special regard to the radiological field.

Germany, West↗