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Biomedical subjects

V I Levin

Publications and source records attributed to V I Levin.

At least 55 records · Page 3Linked to original sources
PubMed1977

[Physico-chemical properties of the DNP-systems of leukemia cells with different chromosome numbers].

The binding between the components of the isolated DNP-complex proved to be more stable in leukemic cells in comparison with the normal lymphoid spleen cells. This conclusion was based on the investigation of the thermomechanical and disaggregation properties of the supramolecular DNP systems isolated from leukemic cells. The change in the isolated DNP-complex were independent of the subpopulation variants of the leukemic lymphatic cells and their chromosome set (diploid or hyperdiploid). The observed changes in the chromatin properties were more specific for leukemic cells than the changes in thechromosome number.

Animals↗
PubMed1976

[Relationship between the development of experimental leukemia and animals' capacity for a humoral immune response].

The tests on AKR and C57BL mice of different age were conducted using experimental models of transplanted Gross leukemia (the first passage), Pujman leukemia and spontaneous AKR mouse leukemia. An inverse relationship between the ability of mice to produce humoral antibodies and their susceptibility to transplantation of singeneic leukemic cells and the incidence of spontaneous leukemia has been established. The differences in the ability of the animals to develop immune response to a heterologous antigen were connected with the physiological processes of the aging organism. The data obtained indicated that the failure of one of the links of immunity did not always result in a higher risk of tumor development.

Animals↗