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Biomedical subjects

T Weiss

Publications and source records attributed to T Weiss.

At least 181 records · Page 10Linked to original sources
PubMed1980

[Quantitative radioaerosol lung imaging in healthy subjects and in patients with chronic obstructive lung disease (author's transl)].

A quantitative method for study of the penetration, deposition pattern and clearance of inhaled particles (O,5-micron-99Tc-labeled human serum millimicrospheres) in the lung is described. 10 healthy subjects and 15 patients with chronic obstructive lung disease (COLD) were studied. For both groups significant differences in the mean values of two indices describing peripheral particle penetration and particle distribution homogeneity were observed. Mucociliary efficiency has been assessed by evaluating aerosol clearance rates from the whole right lung and from upper, middle, lower, perihilar and peripheral zones of the right lung field. Whereas the total lung clearance of both groups showed no marked difference, there was a statistical significant clearance delay in the patient's group upper and peripheral lung area.

Adult↗
PubMed1979

[Quantitative computerized tomographic bone mineral analysis in patients treated by regular haemodialysis (author's transl)].

Quantitative bone measurement has been done on the forearms of 40 patients (aged 20 to 67 years) undergoing long-term haemodialysis treatment. It turned out that trabecular bone shows a more substantial change of the mineralization than does cortical bone. In comparison to an age-correlated undialysed normal range the mean trabecular bone density was found decreased up to 100 percent, whereas cortical bone with a mean demineralization of 10 percent did not appear to be affected by the renal osteodystrophic alterations to that degree. Finally the results show that throughout the course of dialysis treatment there was a trend toward distinct loss of bone mineral with time. No relationship could be demonstrated between the bone mineral values and various biochemical parameters. The estimation of osseous mineral content in both trabecular and cortical bone was done with the aid of an improved computer assisted tomographic method introduced by Rutherford and Pullan.

Adult↗
PubMed1978

[Hydroxylapatite ceramics--a bone-like biomaterial. Preliminary report].

Inorganical materials are being increasingly tried out in surgery and periodontal surgery for reconstructing bone defects. This paper discusses the biocompatibility and biofunctionality of different implant materials and presents a new hydroxyapatite ceramic material, of which a good bioactive behaviour is expected.

Biocompatible Materials↗
PubMed1975

[Sputum conversion and behavior of cavitations in the years 1967-1973].

The results of chemotherapy based on an intersanatorial study of 3306 patients with active pulmonary tuberculosis are presented. In 1967 sputum conversion was achieved in 93%; since 1970 the results have been better, with conversion in 96-97%. From 1967 to 1972 the cavitations disappeared in 51-57% of patients with cavitary disease, but in 1972 and 1973 only in 47% and 36% respectively.

Humans↗
PubMed1975

Vagally mediated suppression of premature ventricular contractions in man.

Twelve patients with PVC's were studied to assess the possible role of the vagus nerves in suppressing PVC's. All were without significant heart disease and under forty years of age. A series of five autonomically active drugs, including vagotonic and vagolytic agents, was administered intravenously, each drug being given after the effects of the previous one had abated. Two of the patients did not have PVC's at the time of study. Of the remaining ten patients, five showed vagally mediated suppression of PVC's. Phenylephrine (40 to 60 mug per minute) reduced HR, from an average of 63.2 bpm to 48.5 bpm by a vagally mediated reflex, and decreased PVC incidence in all five patients. The per cent of ventricular heart beats which were PVC's (per cent PVC) decreased from an average of 18.2 per cent to 3.2 per cent in these patients (p smaller than 0.005 in each case). Edrophonium (10 mg.) produced less bradycardia and less reliable PVC suppression. In two of these five patients, atropine (1.5 mg.) increased PVC incidence markedly, although the per cent PVC did not change significantly because of the concomitant tachycardia. These data suggest that strongly increased vagal tone can suppress PVC's in a significant percentage of such patients. This finding in man extends previous animal work which has shown a protective role of the vagus against ventricular arrhythmias under certain conditions.

Adult↗