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Biomedical subjects

T Weiss

Publications and source records attributed to T Weiss.

197 records · Page 11Linked to original sources
PubMedDate not supplied

Thickness shear mode resonators ("mass-sensitive devices") in bioanalysis.

A short overview of function and experimental set-ups of acoustic wave devices is given which, in contrast to other bioanalysis techniques, are based on a mechanical transduction mechanism. The most frequently used device is the thickness shear mode resonator (TSMR), which in the last few years was intensively employed in biosensor applications. TSMR biosensor studies in the field of nucleic acid interaction, adsorption of proteins to surfaces and immunosensing are reviewed. A main point concerns the interpretation of the sensor response not only in terms of mass loading, which underestimates the capabilities of these devices.

Acoustics↗
PubMedDate not supplied

[Computer tomographic evaluation of the lumbar syndrome in the degeneratively changed lumbar spine].

Computed axial tomograms of the lumbar spine of 318 patients suffering from "sciatica" were studied retrospectively. In 66% of these substantial evidence of degenerative disease of the spine was present. This condition, if severe, may produce confusing scan data and consequently complicate the diagnosis of disc herniation. The phenomenon of posterior hypertrophic osteophyte formation being associated with disc herniation is discussed.

Adolescent↗
PubMedDate not supplied

Effects of repeated ambulatory ECG monitoring and relaxation practice on premature ventricular contractions.

Ten patients with premature ventricular contractions (PVCs) were studied to assess the effects of adaptation and relaxation practice on arrhythmia frequency. They had 48 hr of ambulatory ECG monitoring on three occasions: 1) at entry into the study; 2) 4 wk later, after no intervention; and 3) after 4 wk of practicing the relaxation response. Results showed a significant decrease in PVC frequency from the first to the second monitoring, i.e., before relaxation practice. Of eight patients who completed the third monitoring, only three showed a decline in PVC frequency below baseline levels. The group as a whole showed an increase in PVC frequency with relaxation practice, although this was not statistically significant. These findings suggest that there is an important adaptational effect to repeated ambulatory ECG monitoring in PVC patients--namely, a decrease in arrhythmia frequency. Relaxation practice did not produce any clear effect for the overall group.

Adaptation, Physiological↗
PubMedDate not supplied

Effects of beta-adrenergic stimulation and blockade on cardiovascular reactivity, affect, and type A behavior.

The present study examined the acute effects of drugs that stimulate or block sympathetic nervous system activity on components of Type A behavior, affect, and cardiovascular responses to mental stressors. Either propranolol (a beta-adrenergic blocker), isoproterenol (a beta-agonist), or placebo was infused intravenously at different times in 12 healthy males. In two sessions, placebo (saline) was administered first, followed by a structured interview, challenging mental arithmetic test, and completion of affect scales. The procedure was then repeated with one of the active drugs, presented in counterbalanced order. Results indicated reliable drug effects on both heart rate (HR) and systolic blood pressure (SBP) reactivity to the tasks, with change scores to the tasks markedly increased by isoproterenol. Anxiety and hostility ratings paralleled results for HR and BP, with much of this effect being due to higher affect ratings for isoproterenol. The effect of the drugs on Type A behavior was unexpected, with global Type A and several components lowered by isoproterenol and unaffected by propranolol. These data are discussed in terms of the interfering effects of anxiety on Type A speech components. The influence of isoproterenol on affect and reactivity might reflect the physiologic action of a beta 2-adrenergic positive feedback loop which increases release of endogenous norepinephrine, and/or potentiating effects of emotion on reactivity to stress.

Adult↗
PubMedDate not supplied

Care provided by VA mobile clinic staff during Northridge earthquake relief.

INTRODUCTION: From 25 January 1994 to 02 February 1994, staff aboard four Veterans Affairs Mobile Clinics treated Northridge earthquake victims. This study examined the types of conditions treated by Clinic staff during the disaster. METHODS: A descriptive case series using 1,123 ambulatory encounter forms was undertaken. Case-mix was assessed by classifying diagnoses into 120 possible diagnostic clusters. RESULTS: Forty-five percent of patients were infants or children and 60% were female. The primary diagnoses were characterized by acute conditions: 1) upper respiratory infection (34.6%); 2) stress reactions (11.9%); 3) otitis media (10.1%); and injuries (8%). Two-thirds of the infants and children either had an upper respiratory infection (46.4%) or otitis media (20.1%). Increasing age indicated an increased likelihood of stress and anxiety reactions. CONCLUSIONS: The results provide additional information for agencies involved in planning for and responding to disasters. Based on the types of conditions diagnosed at the VA mobile clinics (i.e., a high prevalence of acute conditions, including stress and anxiety reactions, and the large numbers of children), staff trained in primary care, mental health, and pediatrics should be considered for relief missions that begin several days after an event resulting in a disaster.

Adolescent↗
PubMedDate not supplied

[The dynamics of the parameters of central nervous activation as a correlate of the motor image].

EEG changes were studied in the case of real movements (wrestlers training) and also in the case of imagination of motor activity (ideomotor training). Statistically significant increases were found of the average frequency of oscillations in the EEG alpha-range and simultaneously typical vegetative changes. Thus, imagination of motor activity may serve as a model for studying the CNS activation processes in connection with the realization of real motor activity.

Adult↗
PubMedDate not supplied

Ehlers-Danlos syndrome presenting as rheumatic manifestations in the child.

Nine patients with Ehlers-Danlos syndrome (EDS) presented with joint complaints. This represented 5% of the new pediatric arthritis patients seen over a 6-month period. All 9 patients had a history of double-jointedness, and 7 had arthralgias associated with increased physical activity. On physical examination all had hypermobile joints, 7 had joint tenderness, but none had joint swelling. Based on the presence of other features including hyperextensible skin, widened scars, and cardiac clicks and murmurs, 8 were categorized as EDS Type II and 1 as EDS Type III. It posed a significant problem because the diagnosis had not been previously entertained before consultation and erroneous diagnosis had been made. Therefore, EDS should be included in the differential diagnosis of polyarthralgia in the child.

Adolescent↗