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Biomedical subjects

T Kiss

Publications and source records attributed to T Kiss.

At least 163 records · Page 9Linked to original sources
PubMed1977

Electrical properties of the cardiac muscle cell membrane and its role in the excitation-contraction coupling.

During extracellular stimulation, the electrical properties of the cardiac muscle cell membrane were investigated by means of intracellular microelectrodes. The current-voltage characteristic was S-shaped, and showed non-linearity over given voltage ranges in hyperpolarizing and depolarizing directions as well. The space constant of the membrane was 1.7 +/- 0.1 mm, which decreased after treatment with Ca-free or hypertonic solutions. The mean membrane time constant was 70 msec. and the input resistance was about 8 Mohm. The specific membrane resistance (Rm) and capacity (Cm) were 20 000 ohm.cm2 and 5--6 muF/cm2, respectively. After glycerol treatment the Rm decreased to 10 000 ohm.cm2 and the Cm to 4--4.5 muF/cm2. On the basis of our results it seems reasonable to suggest that the functional relationships between muscle cells might be realized through low resistance junctions, and the effectiveness of these junctions appears to be weakened both by Ca-free solution and glycerol treatment. The specific membrane capacity was lowered by 20 per cent, after treatment with a hypertonic solution, however 60 per cent of the contractility remained unchanged. Thus, we conclude; 1. a part of the Cm originates from the infoldings of the surface membrane, and 2. the snail heart muscle cells are insensitive to glycerol treatment. Since the excitation-contraction (E-C) was not affected by the glycerol treatment it can be assumed that in snail heart the coupling of the E-C is a "direct coupling" similarly to other heart, smooth and slow muscles.

Animals↗
PubMed1977

[Changes in the actual oxygen level of the liver in barbiturate-halothane anesthesia].

The changes in acutal O2-level of the liver were studied in 20 dogs under barbiturate-halothane anaesthesia by means of a RADELKIS OH-102 type polarograph. A thread was led under the hepatic artery and the socalled "ligature test" applied. Occlusion of the vessel lasted 60 s in each measurement. A reactive hyperaemia was observed after the administration of barbiturat and halothane amounting to 40 and 75 per cent, respectively. In the authors' opinion the new method opens new prospects to the study of physiological changes taking place in the liver.

Anesthesia, General↗
PubMed1975

In situ preformed auto-alloplastic replacement in the treatment of femoropopliteal vascular obstruction.

A method of in situ preformed auto-alloplastic replacement for the treatment of long femoro-poplitela vascular obstructions is described on the basis of highly promising experimental results. A macropouous tube made of aplastic net and obturated with a silicone rubber mandril was implanted next to the obstructed vascular section. The two ends of the live auto-alloplastic tube formed in situ around the mandril were joined in a second operation to the femoral and popliteal arteries. Early experience is described on grounds of four cases, together with the current and possible future indications of the operation.

Adult↗