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Biomedical subjects

S Torii

Publications and source records attributed to S Torii.

At least 199 records · Page 11Linked to original sources
PubMed1984

Epigastrius with omphalocele--report of a case.

An epigastrius (parasitic twinning in the epigastrium) was delivered via the vaginal route spontaneously and died 37 days later. The autosite had cardiac hypertrophy with VSD, PDA, and PFO and an omphalocele. The liver was partly conjoined. There was a small swelling at the lower part of the autosite's bifurcated sternum to which the parasitic left pelvis and lower extremity were attached. On the second day after birth, parasitectomy was performed. The amputated specimens consisted of a small left pelvic girdle with a free extremity, a scrotal mass, nipplelike structures and two small protuberances externally. The liver, intestines, two testes, one kidney, one ureter, and the bladder were contained within the omphalocele. Although all of the organs and external structures of the parasite had abnormal histopathological findings, differentiated muscle fibers and submucous and/or myenteric plexus were observed.

Abnormalities, Severe Teratoid↗
PubMed1984

Effects of irradiation of skin flaps.

The reaction of skin flaps to irradiation and the optimum postoperative time for irradiation was studied in the rat. Flaps showed different reactions depending on the time of irradiation. There was a correlation between the radiosensitivity and the vascularity of the flap. Those flaps in the marginal hypovascular stage of revascularization showed reactions similar to normal skin. However, severe adverse reactions were observed in the marginal hypervascular stage.

Angiography↗
PubMed1984

Experimental study of dermal grafts for reconstruction of oral mucosa.

Mucosal defects in the oral cavities of 35 dogs were repaired with reversed dermal grafts, full-thickness skin grafts, and dermal grafts. Comparative observations were made for up to two years to analyze the healing processes. The reversed dermal grafts were covered by surrounding mucosal epithelium and formed normal mucosal tissue that maintained its characteristics for two years. Histologic and scanning electron microscopic examination revealed that the epithelial appendages underwent degeneration, presumably through being embedded by the grafting of the dermis inside out. Epithelialization of the dermal grafts occurred from both surrounding mucosal epithelium and ancillary skin appendages. The full-thickness skin grafts maintained their original structure and function over the two-year observation period. It appears from this investigation that the reversed dermal graft method has definite advantages over full-thickness skin grafting and dermal grafting.

Animals↗
PubMed1984

Dynamic vascular changes in free skin grafts.

Vascular changes in full-thickness skin grafts in rats were examined at various intervals after grafting using microangiography. The grafted skin and its bed showed dynamic vascular changes that were considered to be related to release of an " angiogenetic factor" produced by the skin under oxygen-deficient conditions such as ischemia. The first filling of contrast medium in the grafts was observed 24 hours after grafting. Both primary and secondary revascularization were observed.

Angiography↗
PubMed1984

Five antigens on human T cells detected by mouse monoclonal antibodies.

Five antigen systems were defined by the monoclonal antibodies (MoAb) produced against mature T cells. The antigens recognized were grouped into two categories based on the antigen distribution on T cells. (a) Tp 120 [mol. wt 120 kilodaltons (120kD)] and Tp40 (40kD), these are on most peripheral T cells, but not on any other cell lineages, i.e. pan-T antigen. (b) Ts32 (32kD), Ts145 (145kD) and TsA (not determined), these antigens are present only on certain populations of peripheral T cells, i.e., T subset antigen. Among these five, Ts145 and TsA are probably novel T cell antigens. Cell surface phenotypes of leukaemias and lymphomas were typed with these MoAb. Ia like antigen negative, null cell type acute lymphocytic leukaemia (Ia- null ALL) are Tp40+, suggesting that this type of ALL belongs to a T cell lineage. T cell ALL (T-ALL) and lymphoblastic lymphoma (LL) were both Tp40+, Ts32+, TsA+ and a half of the cases were Tp120+, but the expression of Tp40 was stronger on LL cells. Mature T cell (T2) lymphoma and adult T cell leukaemia (ATL) were Tp120+, TsA+, while Tp40 was weakly expressed on only one third of the cases. These MoAb were found to be useful to estimate the origin of various T cell malignancies.

Animals↗
PubMed1984

Postoperative irradiation after reconstructive surgery: comparative study of radiosensitivity between free-skin grafts and skin flaps.

Radiation effects after reconstructive surgery (free-skin grafts and skin flaps) were studied in the rat, and the optimum time for irradiation was determined. The radiosensitivity of both free-skin grafts and skin flaps showed the same trend depending on time of irradiation after operation. The grafts or flaps irradiated in the hypervascular stage showed severe reactions to irradiation, whereas those irradiated in the hypovascular stage showed milder reactions in gross and microangiographic observation. Vascular damage should be given primary consideration when deciding the proper time for irradiation after reconstructive surgery. In general, free-skin grafts showed more severe reactions than skin flaps, especially in the grafts irradiated in the early stage after operation. The experimental results of this study cannot be readily transferred to a clinical setting, but they suggest that postoperative irradiation could be begun 3 to 4 weeks after operation with respect to graft or flap survival, and the results of the clinical cases almost coincide with these experimental results.

Angiography↗
PubMed1984

Bone marrow transplantation for immunodeficiency.

Bone marrow transplantation for severe combined immunodeficiency disease was studied. Clinical and immunological analysis of four patients showed marked impairment of both humoral and cellular immune functions, suggesting lymphoid stem cell defect. Two of them received successful bone marrow transplantation. The clinical course and process of immunological reconstitution after bone marrow transplantation in these two cases was presented. Some characteristics of bone marrow transplantation for severe combined immunodeficiency disease were discussed in comparison with those of malignant hematologic disorders. Future directions of bone marrow transplantation for severe combined immunodeficiency disease, e.g., transplantation from an HLA incompatible parental donor, were also discussed.

Adolescent↗