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Biomedical subjects

S Torii

Publications and source records attributed to S Torii.

At least 181 records · Page 10Linked to original sources
PubMed1987

Reverse-flow island flap: clinical report and venous drainage.

Twenty-two reverse-flow island flaps were transferred. These included peroneal, forearm, anterior tibial, and temporal flaps. Sixteen of 22 flaps survived completely. We encountered partial necrosis in 4 flaps and total necrosis in only 2 flaps. We credit this success to the reliability and availability of the peroneal, forearm, and temporal flaps; but we do not encourage use of the anterior tibial flap. The flaps that survived well did not show any signs of venous congestion. The advantage of the reverse-flow island flap is that it can be transferred from a proximal to a distal location. Using cadavers and fresh amputated limbs, studies on venous drainage of the reverse-flow island flap were performed. The venae comitantes had numerous venous valves and communicating branches, but more than sufficient reflux of the venous blood occurred through the valves at pressures of 90 to 105 cmH2O. We believe that the venous drainage of the reverse-flow island flap occurs as a result of reflux actions at the valve, communicating branches between the venae comitantes, and bypass vessels around the valves.

Adult↗
PubMed1987

[99mTc-DMSA renal uptake in urological diseases measured from renal tomographic images using single photon emission computed tomography (SPECT)].

To determine renal function, 99mTc-DMSA renal uptake was measured from renal tomographic images obtained by single photon emission computed tomography (SPECT). A total of 77 tests was conducted on 73 patients with various diseases in the kidneys and urinary tract to determine renal uptake. The correlation coefficient(r) between total renal volume and total renal uptake was 0.3509 and that between renal volume and uptake of 143 kidneys was 0.5433. In 62 patients whose creatinine clearance could be measured, the correlation coefficient between creatinine clearance and total renal volume was 0.2352, and that between creatinine clearance and total renal uptake was 0.8854, that is, creatinine clearance correlated well with renal uptake. Renal volume and uptake determined in 10 normal male and 10 normal female adults were 220 ml and 26.8% for the right kidney and 239 ml and 27.6% for the left kidney for the males and 206 ml and 26.4% (right) and 237 ml and 27.9% (left) for the females. This method, which requires no blood or urine collection, is very useful as an individual kidney function test to evaluate individual kidney function and to understand kidney function before and after operation in patients with renal and urinary diseases.

Adolescent↗
PubMed1987

Preservation of natural killer and interleukin-2 activated killer cell activity in ataxia-telangiectasia with T cell deficiency.

Peripheral blood mononuclear cells (PBMs) from 6 patients with ataxia-telangiectasia (AT) were studied by 5 kinds of cell-mediated cytotoxicity systems. Decrease in cell mediated lympholysis (CML) activity to allogeneic lymphocytes was observed in all 6 AT patients who had low numbers of OKT-3+ cells. These patients also showed decreased proliferative responses to phytohemagglutinin stimulation and allogeneic lymphocytes. In contrast, antibody-dependent cell-mediated cytotoxicity (ADCC) activity and natural killer (NK) activity were comparable with those in normal controls. In addition, PBMs from these AT patients activated by in vitro stimulation with allogeneic PBMs or interleukin-2 were able to acquire lytic activity against NK-insensitive target cells. The phenotypes of these effectors determined by complement-mediated lysis were OKT-3- and Leu-11+, suggesting that they were derived from NK cell lineage. Thus, AT patients with severe T cell defects were found to maintain a normal range of NK, ADCC, MLC-activated and lymphokine-activated killer activity.

Adolescent↗
PubMed1986

In vitro analysis of lymphocyte functions in common variable immunodeficiency: heterogeneity in B-cell defects.

Ten patients with common variable immunodeficiency were classified into three groups according to the number of circulating B-cells, i.e. B-cells being absent (three patients), very low (three patients) or within the normal range (four patients). The four patients in the last group showed significant proliferative responses to the T-independent B-cell mitogen, formalin-fixed Staphylococcus aureus, Cowan I. Further study of these patients by co-cultures with allogeneic T or B-cells in various combinations with pokeweed mitogen showed that two patients had an intrinsic B-cell defect without T-cell defect. The third patient had a T-cell dysfunction (i.e. his T-cells could only help the B-cells of some individuals) resulting in a defect in Ig production. The T-cells of the fourth patient showed poor helper function towards all controls. All six patients with absent or very low numbers of B-cells in group I and II had normal T-cell helper function. This study demonstrates that the immunological defect in common variable immunodeficiency is most often a B-cell defect at different stages of their differentiation with sometimes an additional T-cell dysfunction.

Adolescent↗
PubMed1986

Conservative treatment for a ruptured extensor tendon on the dorsum of the proximal phalanges of the thumb (mallet thumb).

Of 35 patients with mallet thumb, 25 received conservative coil-splint immobilization treatment. Those who received treatment were able to extend the interphalangeal joints to at least 0 degrees with the exception of four patients. The number of patients who did not respond to the treatment was greater in those 30 years of age or older compared with those 29 years old or younger, but there was no statistically significant difference. Satisfactory extension was observed in 12 patients who received treatment within 2 weeks after sustaining injuries. Four of 10 patients who received treatment 2 weeks or later after the injuries demonstrated poor results. The preferred treatment for mallet thumb is primary surgical repair. However, conservative treatment should be the first choice if there is no skin wound or the conditions at first consultation are not appropriate for surgery.

Adolescent↗
PubMed1986

Brachymetacarpia and brachyphalangia.

The x-ray features of 325 patients, with shortening of the metacarpals and/or phalanges were analyzed. Most patients with congenital hand anomalies (syndactyly, cleft hand, etc.) had a shortened middle phalanx of the small finger only; however, some patients also had a shortened middle phalanx of the index finger. The patients with brachymesophalangia of two and five rays also had a tendency to have shortened middle phalanges of the index and small fingers. Some patients' anomalies, such as shortening of the middle phalanges in both the index and small fingers, did not adequately fit Bell's classification. The patients who had shortened metacarpals sometimes also had shortened middle and distal phalanges and a shortened metatarsus. Combinations of shortened phalanges and/or metacarpals were so numerous that it was impossible to fit them into any simple classification.

Adult↗
PubMed1986

Marginal vascular change in pedicle skin flaps.

The changes of vascular patterns in pedicle skin flaps were studied in rats at various intervals after operation using microangiography, with the following results: (1) Vascular change was observed in the marginal area of the flap after operation, possibly related to the release of an angiogenic factor during anaerobic metabolism. (2) Both primary and secondary revascularization were observed in the flap, but the main process was found to be primary revascularization. (3) Four days after operation, revascularization was observed. (4) Longitudinal rearrangement of the vessels in the flap could not be observed. (5) At sutured areas where the stitches remained, severe vascular reaction continued for a longer period.

Anastomosis, Surgical↗
PubMed1986

[Estimation of 99mTc-dimercaptosuccinic acid renal uptake using single photon emission computed tomography].

Renal function was assessed by measurement of 99mTc-dimercaptosuccinic acid (DMSA) uptake by the kidney based on the transsectional tomographic image obtained by single photon emission computed tomography (SPECT). The renal uptake was expressed as percentage of the total radioactivity detected in the kidney, the volume of which was measured by convolution method, against the amount dosed. Absorption was corrected by GE-STAR method using cut off level of 42%. In order to determine normal range, measurement was made for 40 kidneys of each of 10 male and female volunteers confirmed of having normal kidneys both morphologically and functionally. The average volume of the kidney was 220.4 ml for the right and 239.3 ml for the left for males, and 205.9 ml and 236.5 ml, respectively for females. The renal uptake of radioactivity (at 2 h after injection), was 26.8% for the right and 27.6% for the left for males, with corresponding figures for females being 26.4% and 27.9%, respectively. Distribution range of renal volume and renal uptake was obtained by bivariate analysis with 90% and 95% probability. From these results, our method of renal function determination based on renal uptake of 99mTc-DMSA obtained from renal transactional tomogram by SPECT is considered to be accurate and potentially useful for clinical purpose.

Adult↗
PubMed1985

Congenital anomalies of the little finger.

Clinical features of congenital hypoplastic and extension contractures of the little finger were studied. There are eight groups. Characteristic features of each group are described. Each type has distinguishable clinical features in typical cases, but in some cases the condition of shortening of the phalanges and narrowing of the joint space is not clear.

Contracture↗
PubMed1985

The pectoralis major myocutaneous flap for intraoral reconstruction: surgical complications and their treatment.

The pectoralis major myocutaneous (PM-MC) flap was used for intra-oral reconstruction in 7 patients. Major necrosis did not occur in any of the cases, but minor necrosis did in two cases. In 2 cases an oro-cutaneous fistula was observed. Furthermore, in 2 cases severe facial oedema was experienced, which seemed attributable to circulatory disturbance in the part of the face where the flap was inserted. Muscle atrophy of the flap was observed in greater or lesser degree in all cases. In all cases the pectoralis major myocutaneous flap was used for the purpose of intraoral reconstruction. Intraoral reconstruction involves considerations different from transplantation in other sites. It is the purpose of this paper to present an updated review of our experience with 7 consecutive pectoralis major myocutaneous flaps, including the complications and their treatment.

Adult↗