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Biomedical subjects

S Kitamura

Publications and source records attributed to S Kitamura.

At least 973 records · Page 54Linked to original sources
PubMed1983

[Survival and late results following surgical treatment of coronary artery disease].

Two hundred and thirteen patients underwent surgical treatment for coronary artery disease from 1968, May to 1983, Feb. at our Department. Clinical diagnosis was stable angina in 55 patients, unstable angina in 47, angina with complication in 9, myocardial infarction in 54, and post-infarction complication in 48. Two hundred consecutive postoperative patients were evaluated. There were 11 late deaths occurred including 4 cardiac deaths in origin. Causes of late cardiac deaths were sudden death in 2 patients and cardiac decompensation in 2 patients. Reinfarction was seen in 1 out of 2 sudden deaths. This case underwent only left ventricular aneurysmectomy without A-C bypass grafting. Preoperatively, 49.2% of the patients were in NYHA 2, 34.8% in NYHA 3, and 15.9% in NYHA 4, but postoperatively 86.3% in NYHA 1 and 13.7% in NYHA 2. Reoperative surgical indications were native coronary progression in 1 patient, graft obstruction in 1, and ascending aortic aneurysm in 1. Surgical treatment of coronary arterial disease has still many problems to be solved, especially in patient with cardiogenic shock, multi-vessel disease, cerebral vascular disease, abdominal aortic aneurysm and patient of old age. But, we believe the surgical treatment will make much progress with development of myocardial preservation, assisted circulation, membrane oxygenator and simultaneous operative techniques including complete revascularization.

Adolescent↗
PubMed1983

[Long-term follow-up results after aorto-coronary bypass grafting].

One hundred and eighty-two patients had been followed for 1 year or longer after aorto-coronary bypass grafting ( ACBG ). Four of them died in this follow-up period, one due to cardiac failure, 8 years postoperatively (p.o.), two due to malignant tumor and one due to an accident. About three quarters of patients improved p.o. into NYHA functional classification I, though no patients was in NYHA I preoperatively. More than 90% of patients with successful complete revascularization in left coronary artery and with a patent left anterior descending artery (LAD), improved into NYHA I. Four patients had reoperation due to the occluded graft to LAD in 4 months to 9 years p.o.. There was neither operative death nor late death 6 months to 4 years after reoperation. Patients with successful revascularization in left coronary artery had significant improvement in left ventricular function, but with unsuccessful one had less improvement. The patients with a history of myocardial infarction in successful revascularization in left coronary artery showed remarkable improvement of ejection fraction at rest and in elevation in LVEDP at exercise. These results show myocardial infarction causes irreversible functional and morphological damage and it could not be full recovered even after ACBG .

Adolescent↗
PubMed1983

[Experimental investigation on intrapulmonary and tracheobronchial distribution of ampicillin after administration of a beta-lactam antibiotic, bacampicillin].

Bacampicillin (BAPC) is a esterified derivative of ampicillin (ABPC) developed recently by the Swedish company. In present investigation we measured the concentration of ABPC in plasma, lung and tracheobronchial tissues from normal, pleuritis and pneumonitis male albino rabbits after an oral administration of BAPC. In these 3 groups plasma level of ABPC reached the maximum at 30-50 minutes after oral administration, then showed a gradual decrease. The decaying curves of pleuritis and pneumonitis groups were steeper than that of control group. Plasma level of ABPC in pneumonitis group at the maximum value was about 1/2 comparing with that in control and pleuritis groups. ABPC levels of tracheobronchial tissues in pleuritis and pneumonitis groups were higher than that in control group at 60 minutes after oral administration of BAPC. On the other hand, tissue level of ABPC in control group was higher than that in pleuritis and pneumonitis groups at 120 minutes after oral administration of BAPC. ABPC level of lung tissues (L1 and L5) in control group was higher than that in pleuritis and pneumonitis groups at 60 minutes after oral administration of BAPC, on the other hand ABPC level of L3 in control group was lower than that in pleuritis and pneumonitis groups. ABPC levels of lung tissues (L1 - L5) at 120 minutes after oral administration of BAPC were higher in control group comparing with that in pleuritis and pneumonitis groups.

Administration, Oral↗