Search PubMed⌕ Search

Biomedical subjects

S Jain

Publications and source records attributed to S Jain.

At least 631 records · Page 35Linked to original sources

Brainstem auditory evoked responses in coma due to meningoencephalitis.

Prognosticating the outcome of an unconscious patient continues to pose a serious challenge to the clinicians. BAERs are the latest addition to neurological diagnostic aids for predicting the outcome of coma. The relative value of BAERs in predicting the outcome of 15 comatosed meningoencephalitis patients has been studied. The results points to a rôle of BAERs in the detection of brain stem dysfunction in a large majority of patients. However, when used as a prognostic indicant, the traditional bed-side clinical assessment (GCS and vestibulo-ocular cold caloric response) still holds a slight advantage over advanced technology. BAERs may have a place in assessing brain stem dysfunction in neurologic conditions where an adequate clinical assessment may not be possible.

Adolescent↗

Human infestation by Taenia saginata lasting over 20 years.

A case of a 61-year-old woman with a history of infestation by Taenia saginata lasting over 20 years is described. The patients repeatedly denied eating raw or inadequately cooked beef. Despite many attempts using different taenicides during those years, the patient continued to pass tapeworm segments until niclosamide was administered. Eighteen months after treatment with niclosamide the patient remains symptom-free.

Chronic Disease↗

An investigation of role-taking in histrionic personalities.

Gough's theory that psychopathy stems from a deficiency in role taking, the ability to perceive and evaluate one's own behaviour as it is perceived and evaluated by others in the same culture, was tested. The Socialization scale, developed by Gough to assess role taking, was administered to a group of 20 female psychiatric patients with histrionic personality disorders, and a control group of female depressives of similar age and intelligence. Socialization scores of the histrionic personalities were significantly lower, indicating impaired role taking, and this difference was not attributable to depression of mood. The Socialization scale was a better discriminator between the groups than the scales of two other personality inventories or a test to elicit meta-impressions.

Adult↗

Effect of ranitidine and cimetidine on gastric ulcer healing and recurrence.

Fifty-eight patients with endoscopically confirmed benign gastric ulceration were randomly allocated to treatment with 150 mg ranitidine twice daily, placebo matching ranitidine twice daily, or 200 mg cimetidine three times daily and 400 mg at night. Patients were endoscoped at monthly intervals for up to 3 months, the endoscopist being unaware of the treatment. Significantly more ulcers (p less than 0.05) had healed after 2 months of ranitidine (14 of 18, 78%) and cimetidine (17 of 20, 85%) than with placebo (9 of 20, 45%; p less than 0.05) and after 3 months of ranitidine (15 of 18, 88%) and cimetidine (18 of 20, 90%) than with placebo (11 of 20, 55%; p less than 0.05). Forty-eight patients with healed ulcers were randomly allocated in a double-blind prophylactic study to receive 150 mg ranitidine at night or matching placebo. After 6 months recurrent ulcers were found in 2 of 24 (8%) of patients receiving ranitidine and 10 of 24 (42%) of patients receiving placebo (p less than 0.05). These data indicate that H2-receptor antagonists are significantly better than placebo in healing gastric ulceration and that ranitidine and cimetidine are equally effective. Ranitidine is significantly superior to placebo in preventing gastric ulcer recurrence.

Cimetidine↗

Anesthesia for the application of endotracheal and endobronchial radiation therapy.

High-activity remote afterloading was recently adapted at Memorial Sloan-Kettering Cancer Center for the treatment of carcinoma of the lung recurrent to the major airways. An anesthesia approach is presented which aids in the performance of this beneficial procedure. The remote afterloader is a device containing a high-intensity radioactive source which is applied intraluminally to control both endobronchial and endotracheal tumors. The patient is intubated with an endobronchial or endotracheal tube which facilitates passage and measurement of the Gamma Med catheter. The potential usage for airway maintenance is a secondary benefit. After bronchoscopic placement is verified radiographically, computerized treatment is initiated. The several advantages of this technique are presented.

Anesthesia, Endotracheal↗

Autokinesis and some conditions of fatigue.

Effects of physical, mental, and vigilance fatigue on the autokinetic reports of 48 undergraduate students are described. Eight response measures were taken of the subjects with an apparatus that permitted recording of the apparent motion of the autokinetic stimulus in the same plane as the light source. Presence of the fatigue states was verified by independent measurements. Fatigue conditions facilitated quick and continuous perception of the autokinetic movements. The most perceptual complexity in the patterns of apparent motion was observed under mental fatigue followed by physical and vigilance fatigue, with least in the neutral condition.

Adolescent↗

Effect of transcutaneous nerve stimulation on postoperative pain after thoracotomy.

A prospective randomized double-blind study was undertaken to evaluate the efficacy of transcutaneous nerve stimulation (TNS) in relief of acute post-thoracotomy pain by comparing postoperative narcotic requirements in 22 patients having TNS and in 22 patients having sham electrical stimulation. All patients in both groups had intrathoracic malignancies. When TNS was used, 22.7% of the patients required no narcotics in the first 24 hr postoperatively. All patients having sham stimulation required postoperative narcotics.

Adult↗