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Biomedical subjects

S Jain

Publications and source records attributed to S Jain.

At least 613 records · Page 34Linked to original sources
PubMed1986

Joseph disease in India--report of two families.

Joseph disease (JD) has only rarely been described in families of non-Portuguese ancestry. Two Indian families with an autosomal dominant inherited ataxia are described in this report. The clinical picture resembled the spectrum seen in JD. An interesting feature was the very early manifestation of the disease process in the third generations. Considerable phenotypic variation within one family was another important aspect. These families had always lived in northern India for the past many generations.

Adult↗
PubMed1986

Phagocytosis of Plasmodium chabaudi: modulation by immune serum and antigen in vitro.

The phagocytosis of free Plasmodium chabaudi parasite by resident peritoneal macrophages of mouse was studied in an in vitro system. The effect of antimalarial antiserum (HIS) was assessed by preincubation of parasite macrophages and both parasite and macrophages with HIS prior to use in phagocytic assays. Highest phagocytic index was obtained with HIS pretreated parasites. The two activities viz. opsonic (parasite dependent) and cytophilic (macrophage dependent) were noted to operate independent of each other. The phagocytosis promoting activity was found to be complement dependent. The receptor site for binding of HIS opsonized but not medium opsonized parasite on the surface of macrophages was blocked by pretreatment of these cells with HIS-soluble antigen combination.

Animals↗
PubMed1985

Pure motor hemiparesis due to non-hypertensive putaminal haemorrhage.

The syndrome of pure motor hemiplegia (PMH) has been traditionally regarded to be due to lacunar infarcts at various places in the brain. Recently, attention has been drawn towards various other aetiological factors which have been responsible for this clinical presentation. PMH as a result of hypertensive putaminal haemorrhage is extremely uncommon. A case of PMH as a result of non-hypertensive putaminal haemorrhage is described.

Cerebral Hemorrhage↗
PubMed1985

Multiple sclerosis: Indian experience in the last thirty years.

A total of 354 cases of multiple sclerosis (MS) were collected from various published reports from India over the last three decades. MS is definitely an uncommon disease in India. Certain clinical characteristics, previously noted individually, have been confirmed to exist in India. When compared to MS in Western countries, the Indian cases show a relatively high incidence of optic nerve involvement (both at the onset and during the course of the disease). Neuromyelitis optical is also seen more frequently. MS may be more common in northern as compared to southern India. In isolated studies HLA-B12 has been reported to be associated with MS in India and positive CSF oligoclonal bands have been seen in only 30% of the cases.

Adolescent↗
PubMed1985

Pure motor hemiparesis due to hypertensive putaminal haemorrhage.

A hypertensive woman presenting as pure motor hemiparesis with rapid and complete recovery from the neurological deficit is described. The probable aetiology was primary hypertensive putaminal haemorrhage, as revealed by CT scan. This rare presentation has been described only once earlier and emphasizes the value of CT scanning as a tool for diagnosis of such cases.

Adult↗