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Biomedical subjects

S J Rose

Publications and source records attributed to S J Rose.

At least 73 records · Page 4Linked to original sources

Electromyographic analysis of two techniques for squat lifting.

The purpose of this study was to examine the effects of two different alignments of the lumbar spine and three different loads on electromyographic activity of the erector spinae (ES) and oblique abdominal (OA) muscles during squat lifting. Nineteen healthy subjects (8 men, 11 women) participated in this study. Each subject performed squat lifts both with the lumbar spine aligned in "back-bowed-in" (BBI), or normal, lordosis and with the lumbar spine aligned in "back-bowed-out" (BBO), or relatively less, lordosis. Based on total duration, the lift was divided into two equal phases. Electromyographic activity of each muscle was quantified for each half of the lift and normalized to the total EMG produced by the muscle during a maximal voluntary isometric contraction. A three-way analysis of variance for repeated measures was used to analyze the effects of position of the lumbar spine, timing, and load on the amount of EMG activity during lifting. For all loads, ES muscle activity was greater during the first half of the BBI lift, whereas OA muscle activity was greater during the first half of the lift, regardless of the lifting style (p less than .01). The greater ES and OA muscle activity occurring during the crucial initial period in the BBI lift may provide the best protection for the lumbar spine.

Abdominal Muscles↗

Physical therapy director as professional value setter. A special communication.

The purpose of this special communication is to emphasize the importance of balancing the physical therapy director's dual roles as fiscal manager and professional value setter. We will discuss the need for balancing these roles and our perception that professional values are underemphasized in many hospital-based physical therapy departments. The physical therapy director's professional values of commitment to high standards of patient care, professional growth, and self-discipline are presented, in addition to specific methods of conveying these values to others. These specific methods include providing a clear focus for the department, being active in patient care, and providing specific mechanisms to allow professional growth of staff members in a directed, but flexible, environment. Our contention is that these dual roles are required to maximize fiscal productivity and professional growth of the staff.

Financial Management↗

Comparative comfort of three waveforms used in electrically eliciting quadriceps femoris muscle contractions.

The purpose of this study was to compare the relative comfort levels of electrical stimulation having different waveforms, but otherwise identical current characteristics, delivered percutaneously to normal quadriceps femoris muscles contracting at the same intensity level. The quadriceps femoris muscles of 20 healthy subjects were stimulated to a torque level 60% of that obtained in a maximal voluntary isometric contraction, using pulsed current with a carrier frequency of 2,500 Hz, at 50 pulses per second of 10-msec pulse duration. Three different waveforms were used: sinusoidal, sawtooth (triangular), and square. The relative comfort level of each electrically elicited contraction for each waveform was determined for each subject using a 20-cm-long visual analog scale. The results showed that no one waveform was most comfortable (least uncomfortable) and the difference was significant in what the subjects perceived to be the most comfortable contraction, regardless of waveform (p less than .01). These results indicate that a subject's perception of discomfort changes as the waveform of stimulation varies and that individual preferences exist for different waveforms. Selection of the most comfortable waveform could prove beneficial when the intensity of muscle stimulation is increased.

Electric Stimulation↗

Length and circumference measurements in one-joint and multijoint muscles in rabbits after immobilization.

In this article, we compared changes in the length and circumference of the soleus and the plantaris muscles in rabbits. The rabbits were assigned to a nonimmobilized external control group (n = 4), an experimental shortened-position group (n = 10), or an experimental lengthened-position group (n = 9). One hind limb of each animal in the experimental groups was immobilized in a cast for four weeks to put the muscles in either a shortened or lengthened position. The contralateral limb served as an internal control for the animals in the experimental groups. After the immobilization period, the limbs were fixed in situ, the muscles were dissected, and length and circumference measurements were taken. In both experimental conditions, the immobilized soleus muscles were shorter than their contralateral counterparts (p less than .05); the length of the plantaris muscles did not change. The immobilized muscles had decreased circumference values regardless of the immobilization angle. When compared with the control condition, the shortened soleus muscles had a greater decrease in circumference than did the plantaris muscles. More connective tissue was observed in the muscle bellies of the soleus after immobilization than in the plantaris. Similar significant changes (p less than .05) were found in the nonimmobilized limbs of the animals in the experimental groups. Specifically, the soleus muscles demonstrated length and circumference changes, whereas the plantaris muscles showed changes only in circumference. These findings suggest that when a weight-bearing limb is immobilized, adaptations in gross muscle length and circumference are to be expected in the involved and uninvolved limbs. An assessment of similar adaptations in humans should be a part of the evaluation during recovery.

Analysis of Variance↗

Hamstring muscle strain treated by mobilizing the sacroiliac joint.

The purpose of this study was to compare the effectiveness of two types of treatment of hamstring muscle strains. Twenty patients with hamstring muscle strains were assigned randomly to an Experimental Group (n = 10) or a Control Group (n = 10). Peak torque production of the quadriceps femoris and hamstring muscles and hamstring muscle length were measured before and after treatment. The hamstring muscles of the Experimental and Control groups were treated with moist heat followed by passive stretching. The Experimental Group also received manipulation of the sacroiliac joint. The change in hamstring muscle peak torque was significantly greater for the Experimental Group than for the Control Group (p less than .005). No significant differences existed between the two groups in either quadriceps femoris muscle peak torque or hamstring muscle length. The results of this study suggest a relationship between sacroiliac joint dysfunction and hamstring muscle strain.

Adolescent↗

Dietary management of intestinal lymphangiectasia complicated by short gut syndrome.

The dietary management of a child with intestinal lymphangiectasia complicated by short gut syndrome following surgery at the age of 3 weeks is described. Diets containing amino acids and peptides were not tolerated due to high osmolality. Satisfactory nutrition was achieved by using a feed with low osmolality and containing whole whey protein, maltodextrin, medium-chain triglycerides (MCT) and a small amount of long-chain triglycerides (LCT) to supply essential fatty acids (RD231).

Female↗

Sea urchin actin gene subtypes. Gene number, linkage and evolution.

The actin gene family of the sea urchin Strongylocentrotus purpuratus was analyzed by the genome blot method, using subcloned probes specific to the 3' terminal non-translated actin gene sequence, intervening sequence and coding region probes. We define an actin gene subtype as that gene or set of genes displaying homology with a given 3' terminal sequence probe, when hybridized at 55 degrees C, 0.75 M-Na+. By determining the often polymorphic restriction fragment band pattern displayed in genome blots by each probe, all, or almost all of the actin genes in this species could be classified. Our evidence shows that the S. purpuratus genome probably contains seven to eight actin genes, and these can be assigned to four subtypes. Studies of the expression of the genes (Shott et al., 1983) show that the actin genes of three of these subtypes code for cytoskeletal actins (Cy), while the fourth gives rise to a muscle-specific actin (M). We denote the array of S. purpuratus actin genes indicated by our data as follows. There is a single CyI actin gene, two or possibly three CyII genes (CyIIa, CyIIb, and possibly CyIIc), three CyIII actin genes (CyIIIa, CyIIIb, CyIIIc), and a single M actin gene. Comparative studies were carried out on the actin gene families of five other sea urchin species. At least the CyIIa and CyIIb genes are also linked in the Strongylocentrotus franciscanus genome, and this species also has a CyI gene, an M actin gene and at least two CyIII actin genes. It is not clear whether it also possesses a CyIIc actin gene, or a CyIIIc actin gene. The genome of a more closely related congener, Strongylocentrotus dröbachiensis, includes 3' terminal sequences suggesting the presence of a CyIIc gene. In S. franciscanus and S. dröbachiensis the first intron of the CyI gene has remained homologous with intron sequences of both the CyIIa and CyIIb genes, indicating a common origin of these three linked cytoskeletal actin genes. Of the four S. purpuratus 3' terminal subtype probe sequences only the CyI 3' terminal sequence has been conserved sufficiently during evolution to permit detection outside of the genus Strongylocentrotus. An unexpected observation was that a sequence found only in the 3' untranslated region of the CyII actin gene in the DNA of S. dröbachiensis and S. purpuratus is represented as a large family of interspersed repeat sequences in the genome of S. franciscanus.

Actins↗

Binding of yeast tRNAPhe anticodon arm to Escherichia coli 30 S ribosomes.

A 15-nucleotide fragment of RNA having the sequence of the anticodon arm of yeast tRNAPhe was constructed using T4 RNA ligase. The stoichiometry and binding constant of this oligomer to poly(U)-programmed 30 S ribosomes was found to be identical to that of deacylated tRNAPhe. The anticodon arm and tRNAPhe also compete for the same binding site on the ribosome. These data indicate that the interaction of tRNAPhe with poly(U)-programmed 30 S ribosomes is primarily a result of contacts in the anticodon arm region and not with other parts of the transfer RNA. Since similar oligomers which cannot form a stable helical stem do not bind ribosomes, a clear requirement for the entire anticodon arm structure is demonstrated.

Anticodon↗

Muscle function in rheumatic disease patients treated with corticosteroids.

Clinical and experimental data indicate that long-term corticosteroid use leads to atrophy of the type 2 muscle fibers. The purpose of this study was to characterize and quantify the nature of muscle function in rheumatic disease patients who have been on long-term corticosteroid therapy. Quadriceps function (i.e., peak torque and power) in 19 patients (11 with rheumatoid arthritis, five with systemic lupus erythematosis, and 3 other) and 11 age- and activity-matched normal controls was measured with an isokinetic dynamometer (Cybex II), during four constant velocity movements. Power was significantly lower for the patients at all speeds. At the higher speeds the patients' deficit in power production increased as indicated by a difference in the slopes of power-velocity regression lines. Measures of peak torque could not be consistently used to differentiate the groups. Patients with rheumatic diseases receiving corticosteroids have a decreased ability to generate muscle power. The method described allows for quantification of these deficits in a clinical setting.

Adrenal Cortex Hormones↗

Electromyographic, peak torque, and power relationships during isokinetic movement.

The use of isokinetic measurements for research and clinical practice becomes more meaningful when it can be demonstrated that subjects being tested at multiple velocities are making similar efforts and when the relationships between various biomechanical measures are understood. The purpose of this study was to examine 1) integrated electromyographic activity per second of the quadriceps femoris muscle at four isokinetic speeds (30, 60, 90, and 120 degrees/sec) and 2) the relationship of power to peak torque at each speed. Two groups were tested: "normals" (healthy subjects) and patients undergoing long-term steroid therapy for rheumatic diseases. The integrated electromyographic activity per second did not vary significantly across speeds, indicating that subjects in each group made equivalent efforts at all four speeds. At each speed, for each group, high correlations were found between peak torque and power. Population-specific and speed-specific linear regression equations were calculated that allowed for predictions of power from the more easily obtained clinical measure of peak torque.

Adult↗

Effect of damp on isokinetic measurements.

Meaningful use of isokinetic data requires understanding potential sources of variation and error. The purpose of this study was to examine one possible source of variation: the effect of recorder damp settings on Cybex II torque tracings. The effect of damp settings 0 through 4 at speeds of 30 degrees/sec and 75 degrees/sec was assessed by dropping loads of 13.65 kg and 36.85 kg attached to a lever arm of 30.5 cm on a Cybex II. The effect of damp settings at 180 degrees/sec was examined with the same weights at damp settings 2 and 4. Increasing damp resulted in 1) a decrease in amplitude of the entire torque curve and a decreased measurement of peak torque and 2) a shift of the torque curve to the right (later in time). The data underscore the need to record and to report the damp settings used during isokinetic testing.

Electronics, Medical↗

Muscle mutability. Part 1. General concepts and adaptations to altered patterns of use.

During the past two decades investigators have shown that muscle fiber is highly mutable. A variety of stimuli ranging from patterns of use to the nutritional state of the organism may lead to alterations in fiber structure and function. The purpose of this review is to provide the information necessary to understand muscle fiber mutability (ie, terms and muscle fiber classification schemes) and to critically review the literature about mutability in response to altered patterns of use. The relevance of these studies to physical therapy is discussed, and suggestions for clinical applications are made.

Adult↗