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Biomedical subjects

S J Rose

Publications and source records attributed to S J Rose.

At least 55 records · Page 3Linked to original sources

Peak torque-to-body weight ratios in the trunk: a critical analysis.

The purpose of this study was to document the relationships between body weight and isokinetic extension and flexion peak torque produced by the trunk musculature. Using a dynamometer, we collected isokinetic measurements during trunk flexion and extension at speeds of 60 degrees and 120 degrees/sec on 61 healthy subjects (29 men, 32 women; 20-60 years old) while standing. Extension and flexion peak torque measurements were calculated for each subject at each speed. Male and female subjects' data were analyzed separately. Each subject's body weight was paired with peak torque at each speed, and Pearson product-moment correlation coefficients (r) were calculated. The correlation coefficients ranged from .27 to .39 for extension and from .66 to .70 for flexion, establishing a positive linear relationship between body weight and each of the isokinetic measurements. Body weight accounted for very small proportions of the variance (as low as 7%-15% in extension isokinetic measurements). In attempting to use a client's body weight to predict isokinetic peak torque measurements, the clinician should be aware that a great deal of unaccounted for variance exists. We recommend that clinicians use other variables (eg, activity level, age) in addition to body weight to control for individual differences among healthy subjects when measuring isokinetic trunk extension muscle performance.

Adult↗

On developing expert-based decision-support systems in physical therapy: the NIOSH low back atlas.

We have described the process of the initial development of an expert-based decision-support system for the management of patients with low back syndrome. Important considerations for developing decision-support systems are reviewed, both generally and specifically. The term "expert" is dissected and discussed. Our work so far involved congregation of a number of experts and compilation of a testing protocol. We are now refining the system for specific populations and purposes.

Back Pain↗

Argininosuccinic aciduria--an underdiagnosed cause of neonatal death?

We describe a case of neonatal argininosuccinic aciduria, a condition we suggest is underdiagnosed. Although the clinical presentation can be of overwhelming septicaemia, certain routine biochemical investigations are indicative of this inborn error of urea cycle metabolism.

Amino Acid Metabolism, Inborn Errors↗

Total contact casting in treatment of diabetic plantar ulcers. Controlled clinical trial.

This study compared the treatment of total contact casting (TCC) with traditional dressing treatment (TDT) in the management of diabetic plantar ulcers. Forty patients with diabetes mellitus and a plantar ulcer but with no gross infection, osteomyelitis, or gangrene were randomly assigned to the TCC group (n = 21) or TDT group (n = 19). Age, sex, ratio of insulin-dependent diabetes mellitus to non-insulin-dependent diabetes mellitus, duration of diabetes mellitus, vascular status, size and duration of ulcer, and sensation were not significantly different between groups (P greater than .05). In the experimental group, TCC was applied on the initial visit, and subjects were instructed to limit ambulation to approximately 33% of their usual activity. Subjects in the control group were prescribed dressing changes and accommodative footwear and were instructed to avoid bearing weight on the involved extremity. Ulcers were considered healed if they showed complete skin closure with no drainage. Ulcers were considered not healed if they showed no decrease in size by 6 wk or if infection developed that required hospitalization. In the TCC group, 19 of 21 ulcers healed in 42 +/- 29 days; in the TDT group, 6 of 19 ulcers healed in 65 +/- 29 days. Significantly more ulcers healed (chi 2 = 12.4, P less than .05) and fewer infections developed (chi 2 = 4.1, P less than .05) in the TCC group. We conclude TCC is a successful method of treating diabetic plantar ulcers but requires careful application, close follow-up, and patient compliance with scheduled appointments to minimize complications.

Casts, Surgical↗

Electrically elicited co-contraction of thigh musculature after anterior cruciate ligament surgery. A description and single-case experiment.

The purpose of this article is to describe a method for strengthening the quadriceps femoris muscle in a patient after anterior cruciate ligament (ACL) surgery. The method incorporates electrically elicited co-contraction of the quadriceps femoris and hamstring muscles. A single-case experimental design based on a split-middle (ABAB) technique was used to assess the effects of the systematic administration and withdrawal of electrical stimulation with respect to changes in knee isometric extension and flexion torque and circumferential measurements of the thigh in a patient six weeks after ACL reconstruction. Results show increases in extension and flexion torque and thigh circumferential measurements that are associated with both stimulation (treatment) phases in addition to a maintenance effect demonstrated during the withdrawal phase. In this patient, the technique appears to be effective in increasing muscle strength and circumferential measurements, particularly quadriceps femoris muscle torque. Implications and suggestions for future research are included.

Adult↗

Electrical stimulation versus voluntary exercise in strengthening thigh musculature after anterior cruciate ligament surgery.

Twenty patients who had undergone anterior cruciate ligament reconstructive surgery were placed randomly and independently in an Electrical Stimulation Group (n = 10) or Voluntary Exercise Group (n = 10) to compare the effectiveness of these two muscle-strengthening protocols. Patients in both groups used simultaneous contraction of quadriceps femoris and hamstring muscles during a training regimen that consisted of either voluntary exercise or electrical stimulation trials five days a week for a three-week period within the first six postoperative weeks. After patients completed the training regimen, bilateral maximal isometric measurements of gravity-corrected knee extension and flexion torque were obtained for both groups and percentages were calculated. Results showed that patients in the Electrical Stimulation Group finished the three-week training regimen with higher percentages of both extension and flexion torque when compared with patients in the Voluntary Exercise Group (extension: t = 4.35, p less than .05; flexion; t = 6.64, p less than .05). These results indicate that patients in an electrical stimulation regimen can achieve higher individual thigh musculature strength gains than patients in a voluntary exercise regimen when simultaneous contraction of thigh muscles is prescribed during an early phase of postoperative rehabilitation.

Adult↗

Expression of myosin heavy chain gene in the sea urchin: coregulation with muscle actin transcription in early development.

A fragment of a Strongylocentrotus purpuratus (Sp) myosin heavy chain (MHC) gene was isolated from a genomic recombinant DNA library by cross-reaction with a cloned Drosophila melanogaster (Dm) MHC probe. A portion of a 227-nucleotide Sp coding sequence that is included in this fragment predicts a peptide very closely homologous with a region of the Dm sequence. The MHC gene sequence is present in a single copy per haploid Sp genome, and the gene is utilized in adult as well as embryonic muscle. The quantity of MHC transcript was measured in embryos of various stages by single-strand RNA probe excess titration. Transcripts are not observed until postgastrular stages, after which they accumulate rapidly. The time course of accumulation closely parallels that measured earlier for muscle actin message.

Actins↗

Diabetic plantar ulcers treated by total contact casting. A clinical report.

The purpose of this clinical report is to describe the healing times of plantar ulcers treated by total contact casting (TCC) in nondiabetic and diabetic patients with and without evidence of severe peripheral vascular disease. Thirty patients with 33 chronic plantar ulcers were treated by applying total contact walking casts. Results demonstrate that 27 of 33 ulcers (81.8%) healed in an average time of 43.6 days. Healing times of patients with severe peripheral vascular disease secondary to diabetes mellitus are similar to those of patients without evidence of vascular disease. These results indicate that TCC is an effective and rapid treatment for chronic plantar ulcers in patients with or without vascular compromise secondary to diabetes mellitus. In addition, the results suggest that pressure reduction on the insensitive foot should be considered in treatment.

Casts, Surgical↗

Reliability and validity of goniometric measurements at the knee.

The purposes of this study were to assess the intertester reliability of goniometric measurements at the knee and the validity of the clinical measurements by comparing them to measurements taken from roentgenograms. Thirty healthy subjects between the ages of 20 and 60 years were studied. The subjects were positioned on their right side on a roentgenographic table with their left lower extremity on a stabilizing board that was elevated 15 cm above the table's surface. For standardization of the position, an assistant placed the posterior aspect of the subject's left thigh in contact with two 15-cm pegs, which had been inserted perpendicularly into the stabilizing board. The assistant then moved the left leg to achieve an arbitrary angle of the knee joint and held the limb in that position. Two physical therapists then independently used a standard plastic goniometer to measure the knee joint angle in the sagittal plane using the greater trochanter, the lateral condyle of the femur, the head of the fibula, and the lateral malleolus as bony landmarks. A roentgenogram was taken of the extremity before the subject was moved. Pearson product-moment correlation coefficients (r's) and intraclass correlation coefficients (ICCs) were used to analyze the data. The data analysis revealed that the intertester reliability (r = .98; ICC = .99) and validity (r = .97-.98; ICC = .98-.99) were high. The results of this study indicate that goniometric measurements of the knee joint are both reliable and valid.

Adult↗

Electrically elicited fatigue test of the quadriceps femoris muscle. Description and reliability.

The purposes of this study were to develop an electrically elicited fatigue test (EEFT) that uses electrically elicited isometric muscle contractions and to examine the reliability of this test on a group of healthy individuals. Fifteen subjects were tested on two occasions, one week apart. The subjects were seated and the left leg secured to an isokinetic dynamometer with the knee positioned at 45 degrees of flexion. Maximum voluntary isometric contraction (MVIC) of the quadriceps femoris muscle was obtained and resultant knee extension torque was recorded. The quadriceps femoris muscle then was stimulated 50 times at the current level that elicited a knee extension torque level equal to 60% of that obtained during the MVIC. Percentages of decline in torque were calculated. Test-retest reliability indexes were calculated for the means of contractions 21 to 25 (r = .82, ICC = .83) and for contractions 46 to 50 (r = .92, ICC = .82). The EEFT was found to be reliable and may provide a clinically applicable means of measuring peripheral muscle fatigue.

Adult↗