The effect of magnesium on the hemolysis of calf and adult cattle erythrocytes.
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Biomedical subjects
Publications and source records attributed to S Imre.
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A modified method based on Teitel's original procedure for measuring the filtrability of erythrocytes was described. The filter paper was not placed into a funnel but to the exit at the bottom of a 2 ml glass column. The filtration of the red cell suspension was quantitated by measuring the decrease of the volume in the column.
In the presence of lysolecithin at physiological pH it was found that the increase of ionic strength facilitates the adhesion of hen erythrocytes. In this medium, dibutyryl cyclic adenosine monophosphate (DBcAMP) increases the adhesion index of the cells. If the osmotic pressure is elevated without a proper increase of ionic strength, the lysolecithin induced hemolysis and adhesion are found to be lacking.
A study has been made to investigate the effect of treatment with Leukeran (Chorambucil) on the development of what is known as a loval Shwartzman phenomenon. The experimental results show that it is only in those cases where the leukopoietic capacity of the organism has been fully exhausted that it is possible for the development of this particular phenomenon to be reliably prevented by immunsuppression brought about by treatment with Leukeran.
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