Physiological role of coronary constriction in the tortoise (Emys orbicularis L.).
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Biomedical subjects
Publications and source records attributed to S Imre.
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The authors made an experimental investigation in the dog concerning the evolution of the muscular clearance of phenoxybenzamine in the course of de-shocking procedures. The animals were shocked by hemorrhage and were treated by perfusion of volemic mass and administration of phenoxybenzamine. This substance was flowed in paralell with the hemodynamic parameters and the rhythm of the diuresis. It was noted that the direction and the amplitude of changes concerning the half-life of Na131I do not depend on the blood pressure.
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1,2,5-Trihydroxy-3-methylanthraquinone (4), 2-hydroxy-3-(hydroxymethyl)-anthraquinone (2) and three dihydroxymonomethyl-anthraquinones (5, 6, 7) have been synthesized. 2 and 4 are new synthetic compounds.
The activity of superoxide dismutase (SOD) and the lipid-peroxidation capacity, i.e., the autoxidation of lipids during incubation at 37 degrees C for 3 h under aerobic conditions was measured in liver tissue homogenates of young (1.5-month-old) and old (24-month-old) inbred female Balb/c mice. The lipid peroxidation capacity was found to be significantly higher in young mice than in old ones. The pretreatment of young mice with allopurinol, a specific inhibitor of xanthine oxidase, remarkably decreased the lipid peroxidation capacity without any modification of SOD activity. SOD levels were equal in young and old mice. Our results suggest that the lipid peroxidation capacity of liver tissue depends, not only on the level of polyunsaturated fatty acids, but, in general, also on the state of a finely regulated counterbalance of pro- and antioxidant factors. The autoxidation test seems to be a suitable in vitro method for measuring the lipid peroxidation capacity of liver tissue.