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Biomedical subjects

R Wolf

Publications and source records attributed to R Wolf.

At least 307 records · Page 17Linked to original sources
PubMed1981

Acne with acute systemic reaction (acne fulminans?). Report of a case.

A 17-year-old girl, hospitalized because of severe cystic acne of six weeks' duration, developed symptoms of systemic disease, with fever, accelerated erythrocyte sedimentation rate, leukocytosis, thrombocytosis, arthralgia and anemia. Extensive investigation ruled out other possible causes for the systemic involvement, and there was a prompt response to steroid therapy. This case had features similar to those associated with "acute, febrile, ulcerative conglobate acne with poly-arthralgia," except that there was an absence of ulcerative lesions: nonetheless, the dominant picture was that of cystic involvement. We believe that the use of the term "acne fulminans" for this and similar cases would be appropriate.

Acne Vulgaris↗
PubMed1980

[The radiation dose to the foetus during isotope investigations of the mother].

The radiation dose to the foetus from the application of five different 99mTechnetium compounds during isotope investigation of the mother was investigated. After i-v injection of 100 muCi (3.7 MBq) of 99mTc-compounds into pregnant rats, these were sacrificed during the first, second and third week of pregnancy and radioactivity was determined in the foetuses and in the blood and organs of the mother. From these measurements the proportion of total body activity in individual organs and their specific activity was calculated. From this data the radiation burden to the rat foetuses from the various 99mTc compounds could be evaluated. Making use of phantom studies and the known biokinetic data of technetium compounds in man it was possible to calculate the radiation dose to the human foetus during isotope investigations of the mother.

Animals↗
PubMed1980

[The radiation dose to children bone scintigraphy with 99mTc-phosphate compounds (author's transl)].

In order to determine the radiation dose to children during bone scintigraphy, distribution and excretion measurements on 99mTc-pyrophosphate and 99mTc-diphosphonate were carried out in rats, piglets, children and adults. Because of the more intensive bone metabolism in children, uptake of 43 to 47% is higher than in adults, in whom uptake in the skeleton reaches 33 to 36%. Assuming homogenous distribution of uptake, radiation dose to the skeleton in children of the ages investigated was 51 to 55 mrd per mCi. Bearing in mind the non-homogeneous distribution in the juvenile skeleton, radiation dose at growth point reaches 85 to 95 mrd per mCi.

Adult↗