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Biomedical subjects

R Singh

Publications and source records attributed to R Singh.

At least 757 records · Page 42Linked to original sources
PubMed1978

Estimation of body fat and lean body mass from anthropometric dimensions in adult Indian women.

Mean values and standard deviations of body fat and lean body mass of 65 young Indian women aged 20-25 years were 9.00 kg, SD 6.14 and 36.02 kg, SD 3.99 respectively. Body fat per cent was 18.72 SD 10.48. On selective stepwise multiple linear regression analysis, the measurements selected for predicting body fat % were maximum thigh girth, chest diameter, height up to gluteal furrow and shoulder diameter, all four together giving a multiple correlation coefficient of 0.88. For predicting lean body mass, the measurements selected were stature, upper arm length, lower thigh girth and chest diameter, all four together giving a multiple correlation coefficient of 0.84.

Adipose Tissue↗
PubMed1978

Mycobacterium leprae in the striated muscle of tuberculoid leprosy patients.

Striated muscle specimens from 24 untreated proved cases of tuberculoid leprosy and five healthy normal individuals were studied histopathologically for the evidence of leprous pathology. Atrophy or damage to the muscle fibre was not observed in any patient. Nineteen (79.16%) cases showed evidence of leprosy in striated muscles. Seventeen (70.83%) cases showed scanty histiocytic infiltrate between the muscle fibres. Thirteen (54.16%) cases had acid fast bacilli mostly inside the muscle. There was no correlation between the location of the bacilli and that of the histiocytes; in two cases, acid fast bacilli were seen without the histocyte. The bacilli were solidly staining and were lying singly in the undamaged muscle. There was no evidence of tuberculosis and, in the Control group, none showed any AFB or infiltrate. The presence of lepra bacilli did not depend upon the location of the muscle. Two of the muscle specimens not underneath the cutaneous lesions also had acid fast bacilli. 21.05% of these cases also showed simultaneous involvement of liver and lymph nodes. These are strong evidences of systemic nature of disease in tuberculoid leprosy as well.

Adolescent↗
PubMed1978

Bone-marrow in tuberculoid leprosy.

Twenty-four untreated patients of proved tuberculoid leprosy and five healthy controls were investigated for the involvement of bone-marrow. The cytology was essentially normal and no acid-fast bacilli was seen in the bone-marrow smears.

Adolescent↗
PubMed1978

Third generation infantile syphilis--an unusual presentation.

A case of third generation early congenital syphilis with unusual features is reported and discussed. The infant presented with Livedo reticularis and an ulcer on the right forearm since birth; the underlying radius and ulna showed osteomyelitic changes with sequestrum formation and a pathological fracture. The rest of the skeletal system was normal. The blood STS (VDRL) was reactive at 1:64. The child showed no other evidence of congenital syphilis. Livedo reticularis and bony lesions resolved promptly with penicillin therapy, but abnormal movements at the wrist joint persisted. The mother had pathognomic Hutchinsonian incisors and a reactive VDRL test.

Follow-Up Studies↗
PubMed1977

Mutagenicity of fungal metabolites related to aflatoxin biosynthesis.

Fungal metabolites identified as the intermediates in aflatoxin biosynthetic pathway were screened for their mutagenic activity to Salmonella typhimurium TA98. Norsolorinic acid, averufin, and versiconal acetate were found to possess questionable mutagenic activity, but versicolorin A, and sterigmatocystin were significant mutagens relative to aflatoxin B1. The mutagenic activity appears to be related to the bisfuran and not the anthraquinone moiety of the molecule, even though the latter is a key structure of such potent carcinogenic mycotoxin as luteoskyrin.

Aflatoxins↗