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Biomedical subjects

R Singh

Publications and source records attributed to R Singh.

At least 739 records · Page 41Linked to original sources
PubMed1980

Effect of actinomyces israelii on human peripheral lymphocytes.

Actinomycosis is rare and responds well to antibiotic therapy. The causative organism, Actinomyces israelii which is now considered to be a bacterium, has long been suspected of exerting an immunosuppressive effect. The authors provide further evidence of this in their study of three patients with actinomycosis and four healthy control subjects. Skin reactivity to various standard antigens was depressed in all seven patients. Peripheral lymphocytes from the patients and the control subjects were isolated. A. israelii was added to the cell cultures following challenge with several standard mitogens. Blast transformation in response to phytohemagglutinin was inhibited by A. israelii in all seven subjects, but was preserved in response to concanavalin A and pokeweed mitogen. A. israelii appears capable of inhibiting the subset of human peripheral lymphocytes responsive to phytohemagglutinin stimulation in vitro.

Actinomyces↗
PubMed1979

The incidence of complications during pregnancy after treatment of hyperprolactinemia with bromocriptine in patients with radiologically evident pituitary tumors.

The course of pregnancy achieved after bromocriptine therapy is described in nine patients with radiologically evident prolactin-secreting pituitary tumors. In six patients no complications occurred. No changes in sellar size or secondary endocrine deficiencies developed. In three patients, however, complications developed between the 22nd and 24th weeks of pregnancy. Despite prior external pituitary irradiation, one patient developed transient bitemporal hemianopsia and one patient had apoplexy of the pituitary tumor with transient paresis of the left abducens nerve. A third patient developed parasellar expansion of the pituitary tumor with bone destruction and paresis of the right abducens and oculomotor nerves. After transsphenoidal surgery the paresis of both nerves disappeared. Microscopically, the tissue removed at surgery was a chromophobe adenoma with focal fibrosis and calcifications without recent hemorrhages. In the course of more than 100 pregnancies achieved in The Netherlands after bromocriptine therapy, five patients reportedly developed complications of the pituitary tumor. At present, patients in whom complications can be expected cannot be predicted by the size or configuration of the sella turicica or the magnitude of elevation of the plasma prolactin level. In two patients external pituitary irradiation did not prevent complications during pregnancy.

Adult↗
PubMed1979

Influence of virus infection on the leaf protein yield.

Influence of cowpea mosaic virus (CPMV) and common bean mosaic virus (CBMV) infection on the yield of extractable leaf protein of cowpea cvs. Pusa Phaguni, Pusa Barsati, and Yard Long was studied. An increase as well as decrease in the yield of leaf protein concentrate (LPC), due to virus infection, has been observed. CPMV infection increased LPC yield in all the cowpea cvs., but CBMV decreased it in cys. Pusa Phaguni and Yard Long. Variation in percentage of extractable nitrogen and protein in LPC was also notices. However, total N and protein in leaf and LPC were increased due to virus infection, but total sugar and starch decreased.

Carbohydrates↗
PubMed1979

Microbial transaminase activities and their relationship with bovine rumen metabolites.

Two each adult male crossbred cattle and murrah buffalo were fed a diet of alfalfa hay, chopped wheat straw, and concentrate mixture. Total rumen transaminase activity of cattle was higher than that of buffalo. Rumen protozoal fractions showed higher total transaminase activity than bacterial fractions in both ruminant species. Besides generally studied glutamate oxalacetate transaminase and glutamate pyruvate transaminase, a large number of other microbial transaminases also have been detected in the rumen of both the ruminant species. Bacterial fractions of rumen liquor were devoid of transaminases utilizing tryptophan, threonine, and lysine as their substrates. Ruminal ammonia and nonprotein nitrogen were correlated positively with microbial transaminases in both species. Transamination reactions may be important for assimilation of ruminal ammonia to cellular proteins.

Alanine Transaminase↗