Protein-losing enteropathy following transplantation.
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Biomedical subjects
Publications and source records attributed to R R Bailey.
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This study was undertaken to assess whether the vaginal flora was affected by the method of contraception, and in particular as to whether the incidence of vaginal candidiasis increased when oral contraceptives were used. One thousand and two consecutive vaginal or cervical swabs from women attending a family planning centre were cultured. Candida albicans was isolated from 13% of women using no contraception, 16% using oral contraceptives, and from 9%, 19% and 18% of those using diaphragms, intrauterine contraceptive devices (IUCD) and condoms respectively. These differences were not statistically significant. Women using an IUCD had significantly more Gram-positive cocci cultured than women in any other group, while those using diaphragms had significantly more Gram-negative bacilli. Our clinical impression that the use of oral contraceptives led to an increase in vaginal candidiasis, was not confirmed by this study.
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Augmentin was compared with co-trimoxazole for the treatment of uncomplicated urinary tract infections in general practice. All 28 patients randomly allocated to treatment with co-trimoxazole were cured. Of the 24 patients treated with augmentin 20(83%) were cured. The cure rate with co-trimoxazole was significantly greater (p = 0.039) than with augmentin. One patient treated with co-trimoxazole developed a skin rash. Two patients treated with augmentin developed severe diarrhoea and abdominal pain and a further two light-headedness. Two of the patients who failed augmentin treatment were reinfected with an augmentin-resistant organism. Twelve of the 52 pathogens were resistant to amoxycillin. One of these 12 was also resistant to augmentin and two only moderately sensitive. An additional three patients were excluded from the study because their infecting pathogen was resistant to augmentin. Augmentin would appear to have a place in the treatment of amoxycillin-resistant bacterial infections.
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