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Biomedical subjects

R Prakash

Publications and source records attributed to R Prakash.

At least 91 records · Page 5Linked to original sources
PubMed1984

Status epilepticus with unilateral ECT: case report.

The occurrence of status epilepticus during a course of modified unilateral nondominant electroconvulsive therapy (ECT) in a patient with chronic schizophrenia is described. ECT was continued in this case with no further complication.

Chronic Disease↗
PubMed1983

Usefulness of echocardiographic right ventricular measurements in estimating right ventricular hypertrophy and right ventricular systolic pressure.

Right ventricular wall thickness (T) measurements were made in 111 patients by echocardiography to evaluate their usefulness in diagnossing right ventricular hypertrophy (RVH) and in predicting right ventricular peak systolic pressure (P). Anatomic and echocardiographic findings of RVH were compared in 36 of 111 subjects: diastolic T (dT) and systolic T (sT) had a sensitivity of 90 and 34% and a specificity of 94 and 100%, respectively, in the diagnosis of RVH. Echocardiographic and hemodynamic findings were compared in the remaining 75 of 111 patients undergoing cardiac catheterization: dt was 6.5 +/- 2.7 mm in 46 patients with elevated P (58.2 +/- 30.2 mm Hg) versus 3.8 +/- 0.9 in 29 patients with normal P (26.3 +/- 2.7 mm Hg) (p less than 0.01). The dT and P had a linear correlation (r = 0.92) in 40 patients with right ventricular end-diastolic dimension less than 13 mm/m2. Estimates of P in 22 patients with atrial septal defect and right ventricular end-diastolic dimension greater than 13 mm/m2 were fairly good (r = 0.83). It is concluded that echocardiographic measurements of T are useful in diagnosing RVH and in estimating P.

Adolescent↗
PubMed1983

Reliability of two-dimensional echocardiography in diagnosing fungal endocarditis.

Although the techniques of M-mode and two-dimensional (2D) echocardiography (echo) have been found to be useful in patients with bacterial endocarditis, the 2D findings of fungal endocarditis are not known. In this report, we present the case of a young female narcotic addict with Candida albicans endocarditis in whom we diagnosed a large vegetation by 2D echo. Decision for surgery was made solely on the basis of the 2D-echo findings. We feel that 2D-echo findings are reliable in diagnosing fungal endocarditis because, with this technique, the size, shape, mobility, and exact location of the vegetation can be better identified than by the M-mode echo. In addition, early diagnosis of fungal endocarditis helps in treating the patients with medical and surgical therapy which may result in lower mortality.

Adult↗
PubMed1983

Psychoses with propranolol: a case report.

Functional and organic psychoses have been reported in association with propranolol therapy. The authors report a rare occurrence of both types of psychoses in the same individual at two different times during propranolol therapy.

Adult↗
PubMed1983

Usefulness of two-dimensional echocardiography in diagnosing right ventricular hypertrophy.

The purpose of this study was to evaluate the usefulness of two-dimensional echocardiographic (2D echo) measurements in diagnosing right ventricular hypertrophy (RVH). These measurements of the right atrium and the ventricle were made in 15 patients with right ventricular hypertrophy and in 11 normal subjects and were as follows: right atrium long axis 2.13 +/- 0.42 vs 1.36 +/- 0.11 cm/m2 (p less than 0.001); right atrium short axis 2.78 +/- 0.60 vs 2.06 +/- 0.26 cm/m2 (p less than 0.001); right atrial area 8.81 +/- 2.79 vs 4.00 +/- 0.33 cm2/m2 (p less than 0.001); right ventricular long axis 4.65 +/- 0.64 vs 3.27 +/- 0.49 cm/m2 (p less than 0.001); and right ventricular area 13.02 +/- 3.64 versus 6.19 +/- 0.74 cm2/m2 (p less than 0.001). The 2D echo right atrial area and long axis had a sensitivity and specificity of 100 percent in the diagnosis of right ventricular hypertrophy. We conclude that 2D echo is useful in the diagnosis of right ventricular hypertrophy.

Adolescent↗
PubMed1982

Short-term naloxone administration in schizophrenic and manic patients. A World Health Organization Collaborative Study.

A double-blind study of the behavioral effects of short-term naloxone hydrochloride administration was performed in 32 schizophrenic and 26 manic patients in a World Health Organization collaborative project. There was a significant naloxone-associated reduction in overall physician-rated symptoms in schizophrenic patients concurrently treated with neuroleptic medication (N = 19) but not in medication-free schizophrenics (N = 13). Physician rating of auditory hallucinations showed significant naloxone-associated improvement for the total schizophrenic population, while self-ratings of auditory hallucinations showed improvement only in neuroleptic-treated schizophrenics. While further studies are needed to delineate these effects as to clinical significance, they may bear etiological implications for the psychobiology of schizophrenia, including the possibility of synergistic effects of dopamine and endorphin blockade. Naloxone produced no significant behavioral effects in manic patients. These findings are discussed with relationship to the hypotheses of endorphin involvement in schizophrenia and mania.

Adult↗
PubMed1982

Psychiatric changes associated with an excess of folic acid.

Two patients are described here who showed exacerbation of psychotic behavior during treatment with folic acid. The authors conclude that further investigations are warranted, since some reports indicate the antipsychotic potential of folic acid.

Acute Disease↗
PubMed1982

Reliability of echocardiography in the diagnosis of right ventricular hypertrophy.

The right ventricular (RV) wall thickness and dimension were measured by the technique of echocardiography in 62 patients. Thirty-six of these patients died, and the RV wall thickness was measured at necropsy for comparison with the echocardiographic measurements. The necropsy RV wall thickness measured 3.3 ± 0.6 mm in patients without right ventricular hypertrophy (RVH) and 5.9 ± 0.9 mm in patients with RVH (P<.01). The echocardiographic measurements of the diastolic RV wall thickness correlated well with the necropsy measurements of the RV wall thickness (r=.83). The sensitivity and specificity of the echocardiographic criteria in detecting RVH was superior to the electrocardiographic (ECG) criteria. Furthermore, the echocardiographic technique was useful in evaluating RVH in 18 patients with an abnormal ECG due to right or left bundle branch block or myocardial infarction. We conclude that echocardiography is reliable in diagnosing RVH.

Adolescent↗