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Biomedical subjects

R Prakash

Publications and source records attributed to R Prakash.

At least 109 records · Page 6Linked to original sources
PubMed1981

Echocardiographic diagnosis of right ventricular hypertrophy: correlation with ECG and necropsy findings in 248 patients.

Measurements of right ventricular wall thickness (RVWT) by echocardiography and at necropsy correlated well (r = 0.83) in 36 patients. Echocardiography had a sensitivity of 93% and a specificity of 95% in diagnosing right ventricular hypertrophy (RVH) at necropsy; electrocardiography (ECG) had a sensitivity of 31% and a specificity of 85% in diagnosing RVH. An additional 212 patients were studied by echocardiography and ECG. Based on echocardiographic criteria of RVH (RVWT Greater Than or Equal To 5 mm), 134 of 212 patients had RVH, and 78 were without RVH: the ECG had a sensitivity of 27% and a specificity of 88% for diagnosing RVH when correlated with the echocardiographic criteria. The mean diastolic RVWT was 6.0 +/- 1.4 mm in 134 RVH patients and 3.4 +/- 0.8 mm in 78 no-RVH patients (P Less Than 0.05). Diagnosis of RVH was difficult by ECG in 73 patients due to conduction defects or old myocardial infarction; the RVWT measurements were useful in evaluating RVH in these patients. We conclude that echocardiographic measurements of RVWT are useful in the diagnosis of RVH and are more sensitive than the ECG criteria in adults.

Adolescent↗
PubMed1981

A study of naloxone with schizophrenic and manic patients.

Eleven schizophrenic and three manic patients were randomly administered 0.3 mg/Kg b.wt. of naloxone or placebo in a drug-free state using a double blind procedure. BPRS and CGI were employed for making periodic assessment of mental status; the MRS was additionally used for manic patients. The authors discuss their findings, which are essentially negative.

Adolescent↗
PubMed1978

Determination of right ventricular wall thickness by echocardiogram.

Right ventricular wall-thickness measurements were performed by echocardiography and at necropsy in 25 patients. Correlations were made and found to be good in all subjects (r = .82). The echocardiographic technique was successful in separating nine patients with right ventricular hypertrophy from 16 patients without right ventricular hypertrophy at necropsy. The diagnosis of right ventricular hypertrophy by ECG correlated poorly with necropsy and echocardiographic findings. Right ventricular wall thickness can be accurately measured by echocardiography.

Adult↗
PubMed1978

Echocardiographic evaluation of cardiac function and drug effects in acute myocardial infarction.

The hemodynamic evaluation of patients with acute myocardial infarction (AMI) usually is performed by invasive methods. A prospective echocardiographic study was conducted on 23 AMI patients to determine the feasibility of this technique in evaluating hemodynamics and in measuring the effect of drugs on left ventricular performance. The results showed that: 1) reproducible measurements of left ventricular end-diastolic and end-systolic dimensions can be obtained by echocardiography, and 2) echocardiography can be used in the assessment of the effect of drugs in AMI. As echocardiography is a simple noninvasive procedure, it is well suited for conducting longitudinal studies in patients outside the coronary care unit and in ambulatory AMI patients.

Acute Disease↗
PubMed1978

Second heart sound: a phono-echocardiographic correlation in 20 cardiac patients.

In 20 cardiac patients, a study was made of the relationship between the second heart sound (S2) recorded by phonocardiography and the motion of the aortic valve recorded by simultaneous echocardiography. Since the first component of S2 coincided with closure of the aortic valve in all 20 patients, it is concluded that the origin of the first component of S2 may be related to aortic valve closure.

Adult↗
PubMed1978

Determination of right ventricular wall thickness in systole and diastole. Echocardiographic and necropsy correlation in 32 patients.

To show that right ventricular wall thickness (RVWT) measurements can be made with precision by echocardiography, we correlated these measurements with those obtained at necropsy in 32 terminal patients. The correlation between the echocardiographic diastolic right ventricular wall thickness (mean 4.0 +/- 1.62 mm) and the necropsy measurement (mean 4.3 +/- 1.52 mm) was good (r = 0.83) in all 32 patients with normal or increased right ventricular wall thickness at necropsy. In 19 patients without necropsy evidence of right ventricular hypertrophy (RVWT less than or equal to 4 mm), the mean diastole and systolic right ventricular wall thickness were 3.0 +/- 0.92 mm and 5.1 +/- 1.64 mm, respectively. In 13 patients with necropsy evidence of right ventricular hypertrophy (RVWT greater than or equal to 5 mm), the mean diastolic and systolic right ventricular wall thicknesses were 5.3 +/- 1.56mm and 8.2 +/- 1.88 mm, respectively. We conclude that technically satisfactory echocardiograms of the right ventricular wall thicknesses. Echocardiography can reliably estimate the diastolic wall thickness and may be helpful in the evaluation of right ventricular hypertrophy.

Adult↗
PubMed1978

The taste buds of Suncus murinus (Indian musk shrew).

Taste buds were generally found on the posterior side of the tongue. Neural elements (nerve fibres, mainly thick myelinated, and ganglia arranged in a chain-like fashion) participated in the innervation of the taste buds. Cholinesterase activity was much marked in the bottom of the taste buds, while the marginal surface showed no such activity.

Animals↗
PubMed1977

Echocardiographic appearance of aortic valve vegetations in bacterial endocarditis due to Actinobacillus actinomycetemcomitans.

This report describes the echocardiographic features seen in a case of bacterial endocarditis due to Actinobacillus actinomycetemcomitans. The echocardiogram demonstrated large, bulky clusters of echoes filling the aortic root in diastole which extended to the subvalvular and supravalvular areas. The echocardiographic features mimicked those described in cases of Candida endocarditis. The morphologic appearance of vegetations at surgery correlated with the echocardiographic findings.

Actinobacillus Infections↗
PubMed1977

Echocardiographic pseudoidiopathic hypertrophic subaortic stenosis in a patient with pericardial effusion.

A 26 year old white male with chronic renal failure presented to our institution with a large pericardial effusion. In addition to the effusion, an echocardiogram demonstrated systolic anterior movement of the anterior leaflet of the mitral valve (SAM), suggesting idiopathic hypertrophic subaortic stenosis (IH-S). Pericardiectomy was performed to treat the effusion. After surgery and relief of the effusion, the mitral valve motion returned to normal. It is concluded that SAM can be seen with pericardial effusion in the absence of IHSS.

Adult↗
PubMed1977

Reliability of echocardiography in quantitating pericardial effusion: a prospective study.

A method of estimating the volume of pericardial effusion by echocardiography has used the difference between the cubed diameters at end-diastole of the pericardium and epicardium. To evaluate the reliability of this technique in quantitating the volume of pericardial effusion in a prospective study, 22 echocardiograms were obtained in six patients before and after 11 separate pericardiocenteses. The correlation coefficient between the actual volume of aspirated pericardial effusion and the echocardiographically estimated volume of aspirated pericardial effusion was r = 0.27 (P not significant). The volume of pericardial effusion aspirated was overestimated or underestimated by echocardiography by more than 100 ml in seven of 11 estimations (64 percent) and by more than 150 ml in five of 11 estimations (45 percent). Therefore, although echocardiography is the procedure of choice in diagnosing the presence of pericardial effusion, it is not an entirely accurate method of quantitating the volume of pericardial effusion. However, echocardiography can differentiate a large effusion from a moderate or small effusion.

Adult↗