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Biomedical subjects

R J Rycroft

Publications and source records attributed to R J Rycroft.

At least 37 records · Page 2Linked to original sources
PubMed1998

Contact sensitivity to chromate: comparison at a London contact dermatitis clinic over a 10-year period.

It has been argued that for chromate sensitivity to be reduced, then ferrous sulfate should be added to cement. This has not yet been done in the UK. To explore this further, we have looked at the comparative sensitization rates of patients attending the St. John's Institute of Dermatology Contact Dermatitis Clinic between the years 1982-3 and 1992-3. Patch-test-positive rates for females were not significantly different between the 2 populations studied (1982-3, 1.59% and 1992-3, 1.99% p NS). Similarly, there was no significantly different rate between the males (1982-3, 3.99% and 1992-3, 4.25% p NS) in the same time period. There was no difference in the distribution of eczema in chromate-positive subjects, nor of cobalt co-sensitization, a crude indicator of sensitization via cement. This work demonstrates no appreciable difference in the frequency of chromate sensitivity between the early 1980s and 1990s in London. Adding ferrous sulfate to cement may help to lower the frequency in the future.

Adult↗
PubMed1996

Clinical assessment in the workplace: dermatitis.

The clinical assessment of dermatitis in the workplace is put forward as a series of four decisions: (1) is it dermatitis and not psoriasis, tinea, scabies, etc? (2) Is it contact dermatitis and not atopic, seborrhoeic, discoid, stasis or unclassified eczema? (3) Is it irritant contact dermatitis or allergic contact dermatitis? (4) What is/are the probable cause(s)?

Dermatitis, Occupational↗
PubMed1996

Recurrent focal palmar peeling.

Recurrent focal palmar peeling, previously known as keratolysis exfoliativa, is an idiopathic condition characterized by chronic palmar and occasionally plantar peeling. It can be exacerbated by environmental factors, and may be misdiagnosed as chronic contact dermatitis. Accurate diagnosis is from the history and examination. It is supported by a negative patch test result. Three cases of recurrent focal palmar peeling are presented, of which two were misdiagnosed as chronic dermatitis. Although there are few references on recurrent focal palmar peeling, it is likely to be a common condition that rarely presents to dermatologists because it is largely asymptomatic. A correct diagnosis is essential due to the social, occupational and legal implications if misdiagnosed.

Adult↗
PubMed1996

Variation in response of human skin to irritant challenge.

A major obstacle to the establishment of a protocol for in vivo irritant skin testing in humans is the apparent variability of responses between individuals. This study of the threshold response of normal human skin to a standard irritant (sodium lauryl sulfate 0.3-10%), in a group of 22 subjects, revealed a marked interindividual variation in their threshold reaction. The results demonstrate that this phenomenon does exist and that it will have to be allowed for in future human irritant test systems or assays.

Adult↗