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Biomedical subjects

R D Koch

Publications and source records attributed to R D Koch.

At least 37 records · Page 2Linked to original sources
PubMed1986

Heart rate variability in chronic alcoholics: a follow-up study.

Heart rate variability (HRV) was studied in 11 chronic alcoholic subjects, 1-30 days after the beginning of abstinence and again 5, 12 and 24 weeks later. Two patients could be re-examined after 19 and 22 months, respectively. In the follow-up study, the total patient group showed a statistically significant increase in HRV with prolonged abstinence of at least 6 months. No recovery of efferent vagal function was found in 4 patients. It is suggested that the vagal neuropathy may improve in chronic alcoholics, but perhaps only in patients with a short to moderately long duration of drinking history or a functional rather than an organic vagal damage.

Adult↗
PubMed1986

[Possible uses of Convulsofin liquid in the treatment of pediatric epilepsies].

The effect of Convulsofin-liquidum on several epilepsies and types of seizure in childhood is described. Typical and atypical absences, tonic-clonic seizures of primary generalised epilepsies as well as atonic or myoclonic seizures are considered to be the main indications for the treatment with Convulsofin. To the special advantage of the application in drops especially with infants is referred.

Administration, Oral↗
PubMed1986

[Computer tomography identification of carriers of Duchenne progressive muscular dystrophy].

Comparison of findings obtained by computed tomography of muscles of possible carriers and normal subjects demonstrated that structural changes existed in 31 out of 74 women; the certainty of the information obtained became greater with increasing age. Six of the seven genealogically definite carriers were detected by computed tomography. The present results show that the use of computed tomography is promising for future carrier diagnosis.

Adult↗
PubMed1986

[Iatrogenic peripheral nerve damage and its forensic evaluation].

Iatrogenic peripheral nervous lesions represent a regrettable complication of medical therapy. Legal regulations of the GDR make it possible for the practicing physician to remain an advocate of the patient's interests. The results of an analysis of 11 years of activities in the Magdeburg County Commission of Medical Experts are presented.

Expert Testimony↗
PubMed1986

[Computer tomography studies in myotonic dystrophies].

Besides clinical symptoms, progress and electromyography the computer tomography is a possibility for improvement the diagnostic of myotone dystrophy. Even small changes in muscle structure are detectable and especially m. soleus exhibits early and pronounced alterations. By means of density distribution pattern an improved characterization of the disease is possible. Additional informations are obtained by cerebralcomputertomography. Hints for atrophy of brain tissue are expectable at all patients with myotone dystrophy. According to the presented findings the computer tomography enlarges the diagnostic possibilities at myotone dystrophy.

Adult↗
PubMed1985

[Course of heart beat variability following acute alcohol intake].

Blood pressure, heart rate and mean momentary arrhythmia were measured in 16 healthy test persons before and after acute alcohol ingestion. While the blood pressure remained unchanged, heart rate and mean momentary arrhythmia showed significant differences in comparison to the initial value, in which case the clearer change of the mean momentary arrhythmia in relation to the heart rate emphasizes the sensitivity of the parameter. The results are discussed as a sequel of the increase of sympathetic activity of alcohol/acetaldehyde.

Adult↗
PubMed1985

[Autonomic alcoholic polyneuropathy].

Measurement of heart rate variability was performed in a group of 106 healthy volunteers and 31 alcoholics. The mean momentary arrhythmia of normal individuals shows an exponential decrease with growing age. In 5 of 31 alcoholics a cardiac autonomic neuropathy was found with this parameter. The withdrawing alcoholics had a significant increase of heart rate and decrease of heart rate variability compared to later measurements, what is in agreement with the concept of hyperexcitability in early withdrawal.

Adolescent↗
PubMed1985

Heart rate variability of chronic alcoholics in withdrawal and abstinence.

Measurement of heart rate variability was performed in 106 healthy volunteers and 31 alcoholics. The mean momentary arrhythmia (MMA) of normal individuals showed an exponential decrease with increasing age. Cardiac autonomic neuropathy was found in 5 of 31 alcoholics. In agreement with the concept of hyperexcitability the withdrawing alcoholics had a significant increase in heart rate and decrease in MMA compared to later measurements. The result suggests that the diagnosis of autonomic alcoholic neuropathy may be reliable only after at least a one week period of abstinence from alcohol.

Adolescent↗
PubMed1985

[Neurophysiologic findings in chronic alcohol abuse].

Neurophysiological examinations of 100 long term alcohol dependent patients who were having neuropsychiatric treatment, showed symptoms of polytopic damage of the peripheral and central nervous system. The results show that for recognition of the damage an extensive diagnostic programme must be used.

Adult↗
PubMed1985

[Results of catamnestic studies on the social prognosis of childhood epilepsies].

Owing to the progress in pharmakotherapy the individual prognosis of epilepsy is characterized above all by brainorganic or psychoreactive caused disorders of the adaptability. The results of the examination of 153 children are presented, which were stationary treated for epilepsy. The special problems in the family, the school and in the choice of a job are referred.

Adolescent↗
PubMed1985

[Value of various social and biological risk factors in child development].

The medical reports of 400 children stationarilly treated for several symptoms and syndromes of abnormal behavior were evaluated. Especially important social factors are the in complete family and disorders of the parent-child-relations as well as the insufficient over-coming of educational problems. Children with results from infantile brain damage are especially endangered by a failure of compensation.

Adolescent↗
PubMed1985

[Side effects of bilateral electroconvulsive therapy--comparative clinico-computer tomographic study].

The side effects of a five-times bilateral electric shock therapy were clinically and computer-tomographically investigated. A connection exists between the number of electric shock treatments which are carried out and the expression of a transitory organic psychosyndrome. However, no significant differences in relation to the initial findings were established a week after the completion of the treatment series despite great interindividual differentiation. Neither cerebral oedema or other signs of disturbances were computer-tomographically detectable as results of treatment. CT and clinic findings do not correspond to each other.

Adult↗
PubMed1984

[Percutaneous transluminal angioplasty of carotid stenoses].

The use of percutaneous transluminal angioplasty for the treatment of stenoses of the carotid artery in three patients is reported. In two cases, the artery could be dilated to its original lumen and in the third a significant dilatation was achieved.

Adult↗
PubMed1983

[Clinical, electroencephalographic and computer tomographic studies of children with West and Lennox-Gastaut syndrome].

The results of clinical, electroencephalographic and repeated computed tomographic examination of 14 children suffering from epileptic seizures in connection with the West and Lennox-Gastaud syndrome are analyzed and compared. Computed tomography yields little information regarding the etiology of such forms of epilepsy. Distinct clinical and electroencephalographic findings were accompanied by normal computed tomographic results in a large proportion of the cases. To avoid misinterpretation of computed tomographic findings and consequent prognostic errors in these epileptic cases it is necessary to take possible side effects of ACTH and corticosteroid treatment into account. At the climax of hormone treatment computed tomography revealed imposing changes in the form of generalized atrophy in 10 of the 14 children examined. These receded completely upon termination of hormone treatment.

Adrenocorticotropic Hormone↗