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Biomedical subjects

R D Koch

Publications and source records attributed to R D Koch.

At least 55 records · Page 3Linked to original sources

[Clinical, electroneurographic and neuroautonomic findings in patients with chronic renal insufficiency and following kidney transplantation].

Orientation onsigns of sensomotor polyneuritis seems appropriate for monitoring the status of patients with chronic uremia. The maximum speed of motor and F-wave transmission by the N. fibularis and the mean instantaneous arrhythmia are parameters which, before clinical symptoms appear, permit the accurate assessment of motor and vegetative lesions and may be useful as a basis on which treatment can be corrected.

Adult↗

[Scintigraphic evaluation of posture-dependent stenoses of the cervical cerebrospinal fluid space].

The results obtained by scintillation scanning of the cervical CSF space at maximum ante- and retroflexion in 24 patients show that the method can be recommended for use in the case of cervical myelopathy when the polymorphous early symptoms appear and before myelography. Its use for follow-up examinations is also recommended. The detection of posture induced constriction of the lumen provides additional information and increases the sensitivity considerably because, particularly during retroflexion, minor inflammatory reactions lead to scintigraphically detectable reductions in the liquor space.

Female↗

[Diagnostic value of neuropsychiatric, audiological and electrophysiological examinations of alcohol-dependent patients].

Neuropsychiatric, audiological and electrophysiological examinations performed on 52 patients under neuropsychiatric therapy after long-term alcohol dependence, gave evidence of polytopical impairment of the peripheral and central nervous systems as well as inner ear. The results show that in order to ascertain impairments, a comprehensive diagnostic program is to be applied with special focus on electroneurographic examinations of peripheral nerves. According to the present findings, the latter are also recommended as a screening method, in particular scrutinizing the N. fibularis while also determining the threshold audiograms.

Adult↗

[Quantitative determination of regional cerebral circulation with Xe-133: lst experiences using this method in the clinic].

After injection of the radioactive noble gas Xe133 into the A. carotis interna, the regional blood flow in the brain is determined with a 10-channel measuring unit. From the first clinical evaluation of the findings in 35 patients, the following conclusions can be drawn: 1. In epileptics, a localised hyperaemia very probary indicates a latent increased convulsive activity. 2. The measurement of the cerebral blood flow does not yield a contribution to the diagnosis of the type of cerebral tumours. 3. As a consequence of mass shifting of space occupying processes particularly endangered brain sections, also remote from the focus proper, show a localised pathological hyperaemia (morbid "luxus perfusion"). 4. Of greatest importance is the method for clearing up of pathophysiological relations, the clearing up of questions in connection with the blood/brain barrier function, and for the indications for and estimation of the results of vascular-surgical interventions.

Brain↗

[The F-wave in healthy subjects - origin, derivation, standardization].

The determination of the maximum F-wave conduction speed by means of the photographic superposition technique is a method that can be carried out in a technically simple manner and can give an insight into the peripheral motor neuron up to the anterior horn cell. The values can be determined in a more exact manner than the respective motor conduction speeds. Similar to the motor conduction speed, influencing factors are to be taken into consideration such as the temperature and the age of patients under ten years. The normal values for the N. ulnaris, radialis, fibularis and tibialis are submitted.

Adolescent↗

[Results of an electroencephalographic cross-sectional study of 2- to 4-year-old children after risk-birth in comparison with to normal-birth children of the same age].

The results of an one time electroencephalographic transversal examination of 146 children with syndrome of intrauterine asphyxia aged from 3 to 4 years are compared with the EEG-findings of 87 children of the same age born normally. 82,9% of the 146 children with higher damage susceptibility and 64,4% of the children of the comparison group have an EEG corresponding to the standard criterions of this age group. 8,2% of the children with higher damage susceptibility and 18,4% of the children born normally show in their resting electroencephalogram focal findings with and without spikes or generalized spike potentials. The results indicate, that by reason of the breadth of variation between normal and pathological EEG-findings in infancy data of the type and frequency of pathological EEG-features have only a value if they are compared with the results obtained from healthy children of the same age.

Asphyxia Neonatorum↗

[Diagnosis of brain abscesses by angiography and nuclear medicine methods].

In most cases, abscesses are formed otogenically or rhinogenically. The clinical symptoms may be uncharacteristic. The diagnosis is made by employing nuclear-medical and angiographic procedures. In 40 patients suspected of having a cerebral abscess, transfemoral cerebral angiography and in 14 cases gammaencephalography or cerebral scintigraphy was carried out. Angiographically, cerebral abscesses mostly appear as avascular growths while nuclear-medical or localised increase in the activity concentration suggests a pathological finding. The symptoms are uncharacteristic and can only be attributed to an abscess process in connection with clinical and paraclinical findings.

Adolescent↗

[Experiences in the determination of brain death].

The experience gained in the ascertainment of the brain death in 45 cases permits to draw the following conclusions: 1. The irreversible functional loss of the brain is in the first place diagnosed on the basis of the clinical-neurological findings. 2. The clinical ascertainment of the brain death requires a considerable amount of experience and should be carried out jointly by neurologists and anaesthesiologists. 3. By using cerebral angiography for proving the arrest of the cerebral circulation it is possible to ascertain the brain death earlier, to cut the pending time and to carry out a possibly envisaged removal of an organ in the period before the dropping of temperature and blood pressure.

Adolescent↗

[Indication for and value of scintigraphy of the intracranial cerebrospinal fluid spaces].

The experience gained in 56 scintigraphic examinations of the intracranial cerebrospinal fluid space with differential-diagnostic clearing-up of hydrocephalus, in the demonstration and the localization of liquorrhea and spinal-fluid passage disturbances are reported. The procedure has proved to be very reliable, side-reactions need not be expected when using Yb169-DTPA.

Brain Injuries↗

[Brain tumor diagnosis using 3-detector-gamma-encephalography].

The probability of diagnosis of brain tumours by means of 3-detector-gamma-encephalography (Hg 197-Neohydrin) is higher than that of the scintigraphic procedures so far available. Above all, the diagnostic accuracy of foci with low storage rates and space-occupying processes of the infratentorial region is improved. The short duration of the examination allows the method to be applied as a screening test.

Brain Neoplasms↗

[Radiological pictures of the skull following brain-tumor surgery].

In 90 patients, the majority of whom was operated upon for a brain tumour, we have systematically controlled the post-operative x-ray pictures of the skull. Clips set in during surgery, calcified epiphysis and changes of the sella due to pressure were the most important signs. To complete the follow-up of tumours we should like to propose to use clips not only as a hemostyptic measure, but also to have marks in cases of possible relapses.

Adolescent↗

[Incidence of infantile cerebral lesions in children with behavioral disorders].

The delimitation of behavioural disturbances predominantly due to organic brain lesions from those caused by reactions due to environmental factors has practical importance for drug therapy and pedagogic guidance. Figures on the incidence of infantile brain lesions among children with behavioural disorders range from between 20 to 90%. However, comparison of the results is difficult, because different authors followed different aspects for the evaluation of their material. The authors have collected data from 497 children from the 3 to 15 year-old age group who suffer from behavioural disturbances: history, neurological and psychological findings, electroencephalogram, native x-ray picture of the skull, pneumo-encephalogram and echoencephalogram were reviewed for signs and findings suggesting infantile brain damage. Certain signs of intantile brain lesion were found in 28.6% of the children. Among the apparative diagnostic procedures without impairment to the patients, the electroencephalogram proved particularly suited for the support of the diagnosis. The most accurate data on the localization and extent of the lesion are provided by the pneumo-encephalogram. However, its performance is not possible or justified in each child.

Adolescent↗

[Results of nuclear medical, electroencephalographic, and angiographic examinations after brain tumor operations].

The methods of nuclear medicine and electro-encephalography allow, in combination, in almost every case the answer to the question of the cerebral tumour relapse. Our evaluation confirms the discovery of the greater sensitivity of the isotopic methods with relapses of glioblastomas, while relapses of meningiomas, astrocytomas, oligodendrogliomas and spongioblastomas can be recognized more frequently only by electro-encephalographic methods. The value of angiography is limited in cases of cerebral tumour relapses without pathological vascularisation, since the swelling can spread in the resection cavity without retroaction on the surrounding areas. For this reason vascular displacement (an only be observed very late on. Clinical judgement is furthermore complicated by the fact that after the removal of the primary tumour, often no reposition of the arteries ensues. After our exainations, a negative angiographic condition can be rule out a diagnosis of a relapse which has been established by electro-encephaolographic and isotopic methods.

Astrocytoma↗