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Biomedical subjects

R Berg

Publications and source records attributed to R Berg.

At least 199 records · Page 11Linked to original sources

Clinical and subclinical hepatitis A occurring after immunoglobulin prophylaxis among Swedish UN soldiers in Sinai.

This study was performed to investigate the efficiency of 5 ml of 16.5% immunoglobulin (Ig) with an antibody titer against hepatitis A (anti-HAV) of 1:4000, using the HAVAB RIA technique, as pre-infection prophylaxis in 610 Swedish UN soldiers stationed in Sinai for 6 months. Sera were collected from 553 of these soldiers before, during, and after their service and were tested by the HAVAB technique for anti-HAV. Only 13 of 553 (2.4%) were immune before their service. During the first 5 months in Sinai, only one subclinical case of hepatitis A occurred among the men. Thereafter, two subclinical and four clinical cases occurred, although one of the subclinical cases and the four clinical ones did not occur until after the 6-month period. Thus, the Ig prophylaxis scheme used seems to offer almost complete passive protection for 5 months.

Adult↗

Histological and histochemical studies on the fundic mucosa of the camel's stomach (Camelus dromedarius).

The one-humped camel, like our domestic ruminants, has a capacious compartmentalized stomach and is a ruminating animal. In our studies wer followed the currently predominant opinion that the camel stomach consists of three compartments (Vallenas, cummings, Munnel 1971). The third one of it is considered as the tubular portion following the second compartment or reticulum and extends till to the pylorus. The Tunica mucosa in the terminal dilated part (distal one-fifth) of this third compartment bears at its greater curvature very thick folds enclosing flat furrows which divide the mucosa into nearly regular areas (gastric areas). This portion of the third compartment contains the proper gastric glands (fundic glands) which differ somewhat from those in the advanced ruminants, especially in the arrangement of the parietal cells and the behaviour of the chief cells which can store mucosubstance during fastening or diminishing of the food in the camel.

Animals↗

Surgical treatment of acute evolving anterior myocardial infarction.

A series of 101 consecutive patients underwent coronary revascularization within a mean of 5.8 hours after anterior myocardial infarction. Forty-one patients had obstruction of the left anterior descending coronary artery (LAD), 35 had obstruction of the LAD and of the right or circumflex coronary artery and 25 had obstruction of the LAD and both the right and circumflex coronary arteries. Sixty-four patients (63%) had total occlusion of the LAD. In-hospital mortality was 2%. The total mortality during a mean follow-up of 43 months was 5%, and 90% of the patients were free of angina. Thirty-six patients had repeat coronary arteriography a mean of 13.4 months after operation. Fifty-two of 62 grafts (84%) were patent. Cardiac catheterization and immediate coronary artery bypass grafting in the first hours of anterior myocardial infarction can be done safely and may reduce in-hospital and long-term mortality.

Adult↗

Immediate coronary artery bypass for acute evolving myocardial infarction.

Two hundred twenty-seven consecutive patients had chest pain and electrocardiographic, coronary angiographic, ventriculographic, and retrospective enzyme changes consistent with acute evolving myocardial infarction (AEMI). These patients underwent coronary artery bypass grafting an average of less than 6 hours after the start of chest pain. The mean age was 55.8 years (range 28 to 79 years). Sex, coronary artery involvement, and preoperative and postoperative enzymes and electrocardiograms are presented. Follow-up angiocardiograms done an average of 12.7 months postoperatively revealed 99 patent primary grafts in 102 patients (94.3%). Ejection fractions were normal, unchanged, or improved in 86.3% of the patients. Two ventricular aneurysms measuring less than 2.5 cm in diameter were noted. Surgical in-hospital mortality was 1.76% and first-year mortality was 1.44%. Conventional therapy in 200 AEMI patients treated at the same hospitals resulted in an in-hospital mortality of 11.5%. Follow-up of 213 patients having coronary artery bypass grafting revealed that 14% had mild angina. AEMI interrupted by coronary artery bypass grafting early in the syndrome yields results which are superior to conventional management.

Acute Disease↗

Studies on the histogenesis of the tunica mucosa of the stomach of the Egyptian water buffalo (Bos bubalus L.).

The histogenesis of the ruminal mucosa was studied in 9 buffalo fetuses (CRL 90--730 mm) and one suckling female buffalo calf. The Lamina epithelialis was found to consist of a basal and superficial layer. The former consists firstly of 2--4 cell layers and becomes later reduced to only one, made up to columnar cells; the latter one consists firstly of about 9 cell layers and increases then to 28--35, depending on the ruminal compartment. The epithelium shows its embryological feature, i.e. all nuclei are directed to the luminal cell pole. The first incidence of the ruminal papillary formation in the Egyptian water buffalo is observed in fetuses of 170 mm CRL. The histogenetic steps of the formation of the ruminal papillae are the aggregation of the cells of the basal layer and of the Lamina propria; the undulations with involvement of the basal layer of the Lamina epithelialis, basement membrane and Lamina propria; formation of humps from the undulations; formation of papillae. The papillary primordia are seen first in the Atrium ruminis and in the caudoventral blind sac simultaneously. The suckling calf has still no definite ruminal papillae. Only their tips are projecting to a different extent into the lumen.

Animals↗

Studies on the histogenesis of the tunica mucosa of the stomach of the Egyptian water buffalo (Bos bubalus L.). II. Histogenesis of the reticular mucosa.

In the fetus with 9 cm CRL the reticular mucosa was made up of a Lamina epithelialis and a Lamina Propria/submucosa. The primordia of the reticular crests firstly appeared in the fetus with 16 cm CRL as evaginations of the basal zone of the Lamina epithelialis into the superficial one. Invaginations from the luminal surface of the Lamina epithelialis above the tips of the long reticular crests were formed in the fetus with 27 cm CRL. Aggregations of smooth muscle cells appeared in the cores of the long reticular crests in the fetus with 50 cm CRL. In the fetus with 73 cm CRL invaginations of various depths were formed to separate the reticular crests from the mass of epithelium. The epithelium in the different fetal stages were missing a Stratum corneum.

Animals↗

Fluorometric assay for measurement of viral neuraminidase--application to the rapid detection of influenza virus in nasal wash specimens.

A sensitive assay was developed for the measurement of neuraminidase with use of the 4-methylumbelliferkyl-alph-ketoside of N-acetyl-neuraminic acid as a fluorescent substrate. Neuraminidase activity was detected in preparation containing small quantities of cultivated influenza virus as well as in some nasal wash specimens from human volunteers experimentally infected with influenza A/Alaska/78 virus. Activity due to influenza viral neuraminidase could be distinguished from activity due to bacterial or mammalian (fibroblast) neuraminidase by means of enzyme inhibition with ethylenediaminetetraacetate, a chelating agent. The same substrate could be used in a solid-phase assay to determine the antigenic type of the influenza viral neuraminidase. The fluorescent neuraminidase assay takes 2-4 hr to perform and uses equipment available in many laboratories. Thus, it offers promise for the rapid detection of influenza viruses in cell cultures and clinical specimens.

Animals↗

Site-specific X-chromosome rearrangements from hybrid dysgenesis in Drosophila melanogaster.

When the germ line of Drosophila males is destabilized by a syndrome known as hybrid dysgenesis, X-chromosome rearrangements are found in up to 10 percent of the gametes produced. Some of these aberrations are simple inversions, but many are complex multibreak rearrangements. Furthermore, most of the breakpoints fall into a few highly localized positions on the chromosome. These positions are mostly at points of intercalary heterochromatin and may vary from one strain to the next. the results suggest that they may represent points of insertion of mobile DNA sequences.

Animals↗

Morphological observations on the normal cardiac glands of the camel (Camelus dromedarius).

The camel's stomach consists of 3 compartments. The third one was subdivided according the external and internal appearance into 3 parts: initial dilated part, middle long narrow part and terminal dilated part with a thick wall. The mucosa in the first 2 parts contain simple tubular glands separated by a clearly visible Lamina propria mucosae, heavily infiltrated with lymphocytes which aggregates to form true lymph nodules especially in the retiform of the initial dilated part. It is concluded that these glands are cardiac glands.

Animals↗

A practical method for monitoring diagnostic radiation dosage in the newborn nursery.

Diagnostic radiation exposure in 133 consecutive newborns was studied using a TLD monitoring system. Eighty-eight per cent of dosimeters received less than 1 mSv (100 mrem) total exposure. The mean exposure per chest radiograph was 0.044 +/- 0.023 mSv (4.4 +/- 2.3 mrem). Abdominal surface exposure was 0.053 +/- 0.03 mSv (5.3 +/- 3.0 mrem) for boys and 0.044 +/- 0.021 mSv (4.4 +/- 2.1 mrem) for girls. The gonadal exposure, which was calculated from the abdominal exposure data, was 0.053 +/- 0.030 mSv (5.3 +/- 3.0 mrem) for boys and 0.026 +/- 0.012 mSv (2.6 +/- 1.2 mrem) for girls. The correction factor for beam attenuation over gonads in girls was 0.58. In general, the radiation received by these infants did not exceed the currently published protection limits.

Female↗