Search PubMed⌕ Search

Biomedical subjects

R Berg

Publications and source records attributed to R Berg.

At least 181 records · Page 10Linked to original sources

The prenatal development of the skin in the one-humped camel (Camelus dromedarius).

The epidermis of the camel started its development as a single layer of cuboical cells. The second layer occurred at the fetal stage of C RL 5 cm and the intermediate cell layer at the C RL 10 cm-stage. In the C RL 83 cm - fetus the epidermis is differentiated into the Stratum basale, Stratum spinosum, Stratum granulosum and Stratum corneum. In the dermis the collagenic and reticular fibres were observed in the 2 cm - fetus, and the elastic ones at the C RL 20 cm - stage.

Animals↗

Studies on the histogenesis of the tunica mucosa of the small and large intestines of the camel (Camelus dromedarius). II. Histogenesis of the colonic mucosa.

The colon is at first a simple tube, and its mucosa has a smooth luminal surface, surrounding a previous lumen. At the 150 mm stage the mucosa is thrown into a number of stout projections, each has a vascularized mesenchymal core and an epithelial cloth. These projections are in turn split into finger-like villi by transverse furrows. The villi reach their maximal length at the 260 mm stage and then gradually degenerate and slough into the lumen. The villi were completely disappeared at the 730 mm stage. The colonic glands were firstly observed at the 200 mm stage as downgrowths of the intervillous epithelium and they increase in number by dichotomous division of their bases. The Lamina muscularis mucosae is completely constructed at the 730 mm stage.

Animals↗

Studies on the histogenesis of the tunica mucosa of the small and large intestines of the camel (Camelus dromedarius). I. Histogenesis of the small intestinal mucosa.

The histogenesis of the small intestinal mucosa passes through a previllous stage, comprising development until the formation of villi (at a C RL of about 15 cm), and a villous stage, comprising the further development. In the previllous stage, the mucosa consists of a Lamina epithelialis made up of undifferentiated cells with stratified nuclei and a Lamina propria/submucosa made up of homogeneous mesenchyme. The villi appear as luminal epithelial outgrowths associated with vascularized mesenchymal stalks and their growth advances in a cranio-caudal direction. The intestinal glands were firstly observed at the 26 cm-stage as downgrowths of the intervillous epithelium into the underlying mesenchyme.

Animals↗

Perinatal pharmacokinetics of acetylsalicylic acid.

Pregnant women were treated with infusions of acetylsalicylic acid (ASA). The plasma concentrations of total salicylate or those of ASA and salicylic acid (SA) were determined. The ASA steady state was reached after 2 h of infusion whereas 3 days seemed necessary to reach the steady state of SA. In a further study during the late phase of cervical dilatation (12 min - 2 h before birth) healthy pregnant women were given 1 g ASA as a single i.v. bolus injection. The resulting plasma levels of ASA and SA in the mothers during delivery, the plasma concentrations in umbilical cord blood and in blood obtained from the newborn several hours after birth were measured. With increasing time the SA concentrations in the umbilical cord blood plasma approached those of the mothers. On the other hand, the umbilical cord blood concentrations of ASA did not approach the maternal concentrations, probably because of the ASA esterase activity at the placental barrier. The plasma concentrations in the newborn indicated that the newborn is able to degrade ASA and to excrete SA. However, the velocities are lower than the respective velocities in adults.

Aspirin↗

Prevalence of antibody to hepatitis A in Iceland in relation to age, sex, and number of notified cases of hepatitis.

The prevalence of antibody to hepatitis A virus (anti-HAV) was investigated in 623 outpatients in Iceland. No difference in anti-HAV prevalence according to sex or rural vs. urban residence was found. The prevalence rates in different age groups were found to be comparable to those in the Scandinavian countries, increasing from 1.6% (1/63) in persons below 20 years of age to 66% (51/77) in persons above 60 years of age. The numbers of notified cases of hepatitis (epidemic jaundice) in Iceland during the 20th century showed a pattern of repeated epidemics up to the early 1950s, after which low rates were noted. The incidence of hepatitis dropped 30-fold during the 20th century. Persons born after the latest epidemic in 1952 were positive for anti-HAV in only 4.7% (7/150).

Adolescent↗

Penile malformation and mental health. A controlled psychiatric study of men operated for hypospadias in childhood.

Aspects of mental health were investigated by means of interviews and register data in 34 men operated on for hypospadias in childhood and in 36 matched control subjects. Most hypospadiacs adjust well both in childhood and adult age. However, they reported more neurotic disturbances in their childhood than the controls. Shyness and enuresis were common troubles among the probands, and they had been more timid, isolated and mobbed. Similar although less striking differences in mental health were reported also in adult age. Depression and anxiety were dominating symptoms. The interviewer assessed the hypospadiacs to show more anxiety and to use more immature defence mechanisms and consequently to have less stress tolerance. The probands were further judged to have less capacity for social relations and their overall capacity to utilize existent psychological resources was small as compared to the controls. The findings indicate that hypospadiacs are more prone to neurotic (but not psychotic) disturbances than other young men and have more disturbed social relations. The need for psychological guidance for the boys and their parents is stressed.

Adolescent↗

Studies on the histogenesis of the tunica mucosa of the stomach of the Egyptian water buffalo (Bos bubalus L.) III. Histogenesis of the mucosa of the ventricular sulcus (esophageal groove).

In the fetus with 9 cm CRL the ventricular groove was made up of two lips and a floor. The mucosa consisted of a Lamina epithelialis and a Lamina propria mucosae. The basal zone of the Lamina epithelialis was uneven in the floor of the groove and showed wedge-shaped evaginations into the superficial one. The luminal surface of the Lamina epithelialis of the floor became undulant in the fetus with 27 cm CRL. The Lamina muscularis mucosae became evident in the fetus with 73 cm CRL. In this fetal stage the Lamina epithelialis of the floor became differentiated into the Strata basale, spinosum, granulosum and corneum.

Animals↗

Studies on the histogenesis of the Tunica mucosa of the stomach of the Egyptian water buffalo (Bos bubalus L.). IV. Histogenesis of the omasal mucosa.

In the fetal stage of 9 cm CRL 4 order omasal laminae are present. With increasing age they increase greatly in size and conical papillae are seen projecting from their sides into the lumen. At 27 cm CRL stage sporadic smooth muscle cells in the interlaminar spaces, representing the first appearance of the Lamina muscularis mucosae, become visible in the cores of the laminae in the fetus with 32 cm CRL. A fifth order lamina occurs in the fetus with 32 cm CRL as evaginations of epithelium and the underlying Lamina propria mucosae in the interlaminar spaces. The epithelium becomes stratified squamous keratinized assuming the features of the ruminal epithelium after birth.

Animals↗

Difference in brain densities between chronic alcoholic and normal control patients.

The densities of the brains of 11 chronic alcoholics were compared with those of 11 age-matched normal control subjects. Densities were determined from the density numbers generated by computerized tomography at three levels of the brain-the highest level of the lateral ventricles and the next two higher levels-with adjustments made to control for possible artifacts in the data. The advantage of the dominant hemisphere over the nondominant hemisphere was lessened in alcoholics.

Adult↗

Operated hypospadiacs: late follow-up. Social, sexual, and psychological adaptation.

Thirty-four adult men operated upon for hypospadias in childhood and 36 controls were examined by interview and psychological tests. During childhood hypospadiacs had enuresis, showed shyness, and were mobbed more often than controls. Hypospadiac's sexual debut, but not the first ejaculation, was delayed. Most hypospadiacs had a satisfactory sexual life, albeit restricted to fewer partners. Socially, hypospadiacs showed normal adjustment but had less qualified professions than controls. Hypospadiacs showed a more doubtful sexual identity and greater castration anxiety combined with lesser utilization of cognitive and emotional resources than controls. Early operated hypospadiacs had a more infantile sexual identity than those operated later (less than 5 yr).

Adaptation, Psychological↗

Social and sexual adjustment of men operated for hypospadias during childhood: a controlled study.

In a controlled study 34 men operated on for hypospadias in childhood and 36 control subjects were interviewed concerning their sexual and social adjustment, which at the time of the interviews was shown to be virtually similar in the 2 groups. Most of the hypospadiacs had stable sexual relationships but they had been sexually less active than the controls. The sexual debut of the hypospadiacs was retarded although the age at first ejaculation was the same as for the controls. The hypospadiacs had less qualified professions compared to the controls. The results indicate the possibility of operated hypospadiacs being psychologically different from other men. Fertility seems to be equal in the 2 groups and even patients with severe forms of hypospadias reported fertility. The issue of optimal ambition in surgical repair is discussed in view of the fact that even patients with a less than perfect technical result are able to live a satisfactory sexual life.

Adult↗

[Clinical study of the labour inhibiting effects an side effects of acetylsalicylic acid (ASA) (author's transl)].

In 37 pregnancy women preterm labour was inhibited with intravenous administration of ASA. 20 patients (Group I) had a combined treatment of ASA and Fenoterol. 7 pregnant women (Group II) without successful labour inhibition under Fenoterol were treated with ASA subsequently. In a third group of 10 women we administered ASA alone. The treatment was considered as successful if signs of preterm labour stopped and pregnancy maintained for 7 days or more. In the first group 16, in the second group all patients had been treated successfully. In group III we succeeded in labour inhibiting for more than 7 days in 6 cases. An initial loading dose of 5.5 to 7.0 mn/min ASA had been infused for 24 hours. If preterm labour was stopped, the dosage had been reduced. In all patients dose related but reversible symptoms of vertigo, tinnitus, headache and hyperventilation were seen. Furthermore we found a non-dose-dependent prolongation ( by 30% or normal) of bleeding time. In the fetus respectively the newborn an affection by this ASA treatment could be excluded. We propose inhibition of preterm labour by i.v. ASA administration in all pregnant women if beta-mimetic drugs are not successful or an intolerance is diagnosed. Contraindications for ASA therapy are mentioned.

Aspirin↗