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Biomedical subjects

R Baumgarten

Publications and source records attributed to R Baumgarten.

At least 127 records · Page 7Linked to original sources
PubMed1985

[Effectiveness of combined plasma exchange treatment in fulminant viral hepatitis].

The plasma exchange is an effective measure in the treatment of acute liver failure. The authors report their own first experiences in this field in the management of fulminant viral hepatitis. Four out of 7 treated patients survived. So, the survival rate was augmented from 25 per cent in a control group of 8 patients without plasma exchange to 57.1 per cent. Other necessary therapeutic measures are high energetic nutrition, branched chained amino acids, stimulation of liver cell regeneration, correction of coagulation alterations, and intensive care. The success depends on coma stage in the beginning of treatment. Patients with signs of praecoma should be admitted to specialized centers. The number of such centers should be limited because of the necessary experiences and the high costs of combined plasma exchange treatment of this rare hepatitis complication.

Adolescent↗
PubMed1984

[Immunoprevention of hepatitis B in children of HBsAg-positive pregnant patients].

Children of hepatitis-B-surface-antigen-positive women are, depending upon the degree of maternal infectivity, exposed to a very different risk of hepatitis B. In the GDR the rate of infectious pregnant women is low. The serious consequences of a perinatal hepatitis B, which very often leads to a chronic course and virus carriers, may widely by prevented by immunoprophylaxis. Various methods for the establishment of a risk are described. The hepatitis-B-surface-antigen screening in 28 127 pregnant woman showed 20 = 0,07% of carriers of findings, 4 out of them HBeAg-positive. From the performance of the passive immunisation in 6 babies of HbeAg-positive mothers and 2 newborn without maternal HBe- or anti-HBe-proof and from the results of the control of 17 children, who were not immunized, when there was an anti-HBe-positiveness or when there was no proof of HBe-markers, result recommendations for practice.

Carrier State↗
PubMed1983

[Paracetamol poisoning--clinical aspects and pharmacokinetics].

The analgesic and antipyretic effect of paracetamol and phenacetin is to be traced back to the same pharmacologic active substance. When no therapeutic doses are applied, paracetamol causes severe lesions of the liver parenchyma with often fatal termination. It is reported on the paracetamol intoxication of a 38-year-old landlady, in whom as a sequel of the intoxication a severe lesion of the liver parenchyma and an acute toxic renal failure developed. The understanding of the paracetamol-conditioned lesions takes the knowledge of the course of the reaction of its biotransformation for granted. Since the pharmacokinetics underlies numerous influence factors, there is no foreseeable correlation between toxicity and doses. It seems that also in therapy paracetamol does not cause less side-effects than phenacetin. The discussed use of paracetamol instead of phenacetin is, therefore, critically to be considered.

Acetaminophen↗
PubMed1983

[Acute virus hepatitis - infection hygiene recommendations based on current knowledge].

As to the up to now under the uniform collective notion "infectious hepatitis" notifiable diseases according to the actual stage of realization a group of diseases is concerned which are caused by at least 3 pathogens. Apart from the hepatitis A and B it is the hepatitis non-A/non-B for which an unequivocal differentiation of pathogens with standardized methods of proof is still pending. There is no cross-immunity between the individual virus-caused hepatitides. They behave diversely clinically and epidemiologically. The in very case indicated infection-hygienic measures result from the different duration of infectiousness, the ways and modes of transmission. They concern the hygiene of the hospital and the immunoprophylaxis as well as the separation of persons from the environment of patients who work in S-professions (activity in the branch of food-supply, groups of children). The problems concerning chronic carriers of infectious hepatitis B are hitherto still unclarified. The legal regulations up to now valid for this group of persons, the necessary hospital hygiene when they are admitted and possible future ways of solution for the total problem are explained.

Acute Disease↗