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Biomedical subjects

R A Filly

Publications and source records attributed to R A Filly.

At least 271 records · Page 15Linked to original sources

The placental-subplacental complex: a specific indicator of placental position on ultrasound.

Subplacental tissue frequently appears as a less echogenic zone adjacent to the more echogenic parenchymal texture of the placenta on gray-scale sonograms. This complex of parenchymal structures is useful in specifically localizing placental position and extent, especially in posteriorly positioned placentas, which may be shadowed by the fetus, or in cases in which focally thickened portions of the myometrium or reverberation artifact may simulate the placenta.

Amniotic Fluid↗

In vitro investigation of the origin of echoes with biliary sludge.

To investigate the origin of echoes from "biliary sludge," concentrated bile and bile from 5 patients with ultrasound findings of biliary sludge were examined in a tissue-equivalent phantom before and after filtration through progressively smaller pore sizes. Filtration converted echogenic bile to echo-free bile. Examination of the filtration residue by light microscopy established that the source of echoes in biliary sludge was particles, predominantly pigment granules, with lesser amounts of cholesterol crystals. Partial chemical characterization by determination of vulnerability to different solvents verified that the sludge was mainly calcium bilirubinate.

Bile↗

In vitro investigation of gallstones with computed tomography.

An in vitro investigation of gallstones from 25 patients using computed tomography (CT) was performed). An abdominal phantom was constructed and filled with a matrix with an attenuation value equivalent to normal liver. A condom filled with water and positioned within the phantom simulated the gallbladder. Gallstones were placed in the condom and were scanned, radiographed, measured, and inspected. All gallstones were detectable by CT as filling defects within the condom having CT attenuation values higher or lower than water. Attenuation values ranged from +178 to -188 CT units (scale, +500 to -500). Gallstones containing calcium settled to the bottom of the condom, while calculi containing gas filled fissures rose to the top of the condom.

Adult↗

First trimester molar pregnancy: nonspecific ultrasonographic appearance.

Ultrasonographers and gynecologists have come to anticipate not only a high diagnostic sensitivity of ultrasonic detection of hydatidiform mole, but also that the examination will suggest specifically the correct pathologic diagnosis. Although this appears true for molar gestations examined in the second trimester, molar pregnancies detected in the first trimester do not appear to demonstrate the characteristic features necessary to diagnose this abnormality specifically. Three cases of early molar pregnancy examined in the past year with good quality gray-scale ultrasonographic units failed to demonstrate specific diagnostic findings.

Adult↗

Characterization of biological fluids by ultrasound and computed tomography.

Blood and blood products, and solutions of albumin and chondroitin sulfate of varying concentrations were imaged by ultrasound and computed tomography in a phantom having ultrasonic and CT characteristics of liver tissue. Measurements of CT number, ultrasonic absorption, and viscosity were obtained for selected fluids. All fluids, including concentrated solutions of albumin and chondroitin sulfate having high viscosity, were detectable as echofree regions on ultrasound scans. Acoustical enhancement distal to fluids was noted to decrease in prominence with increasing sound absorption in the fluid. On CT scans, fluids with CT numbers close to those of their surroundings were poorly detected.

Bile↗

Ultrasonic demonstration of endometrial fluid collections unassociated with pregnancy.

Intrauterine fluid collections were demonstrated by ultrasound in 17 non-pregnant patients. In nearly all instances, the surrounding echoes were of low to moderate amplitude. This has been noted previously in women with an ectopic or abnormal intrauterine pregnancy. In 2 patients, a well-defined thick rind of high-amplitude echoes encompassed the fluid, simulating an early gestational sac. Small intrauterine fluid collections were seen most frequently in non-pregnant patients who had vaginal bleeding or inflammation of the endometrium or adnexa.

Abscess↗

Ultrasonic evaluation of normal pancreatic echogenicity and its relationship to fat deposition.

Normal pancreatic ultrasound studies of 28 patients were evaluated as to pancreatic echogenicity and correlated with the morphologic appearance of the pancreas on CT to test the hypothesis that increasing pancreatic echogenicity is related to greater fat infiltration. Statistical analysis indicates that fat is a major but not the only determining factor of increasing echogenicity.

Adipose Tissue↗

Abdominal disease in children: a comparison of computed tomography and ultrasound.

Diagnoses from computed tomographic (CT) and ultrasonic examinations of the abdomen in 29 pediatric patients were reviewed retrospectively to compare the sensitivity and specificity of the two methods for detection of abnormalities and to assess their differential diagnostic accuracies. No difference in sensitivy (87%) and specificity (100%) was observed between the two imaging methods. However, the differential diagnostic accuracy in abnormal cases was greater with CT than ultrasound. The combined information from CT and ultrasound allowed for correct diagnoses in all but three instances. Findings from each technique considered separately would have resulted in erroneous diagnoses in four instances using CT and nine instances using ultrasound. Diagnostic information obtained from CT and ultrasound examinations were complementary in many instances.

Abdomen↗

Intrauterine contraceptive devices: evaluation by sonography.

The sonographic features of intrauterine contraceptive devices (IUD), which allow identification of their intrauterine location, were evaluated in vitro and clinically in 50 patients. Posterior acoustic shadowing was seen in 90% of patients, entrance-exit reflections in 65%, and type-specific morphology in 94% of patients with Lippes Loops and in 81% with Copper 7 devices. Recognition of the characteristic features of the IUD and identification of endometrial mucosa around the IUD will allow unequivocal and accurate determination of its correct intrauterine location.

False Positive Reactions↗

Identification of fetal growth retardation by ultrasonographic estimation of total intrauterine volume.

Recent literature has suggested that total intrauterine volume (TIUV) estimation is useful fir distinguishing normal from growth-retarded fetuses. One hundred seventy-nine measurements of TIUV were obtained from the ultrasonograms taken between 21 and 40 weeks of gestation in 140 patients who delivered average birthweight babies. We constructed a mean curve for TIUV with upper and lower 2.5 and 10% tolerance limits and later evaluated the TIUV's of 16 patients with growth-retarded fetuses. Nine of these fetuses had birthweights below the fifth percentile for gestational age, and in each of these pregnancies the TIUV ultimately fell below the lower 2.5% tolerance limit.

Birth Weight↗

The normal pancreas: acoustic characteristics and frequency of imaging.

This article reports the results of a study designed to evaluate both pancreatic echogenicity and success of visualizing recognizable pancreatic tissue. The acoustic characteristics of the normal pancreas were compared with those of the liver. Of 100 scans reviewed, 65 scans (65 percent) depicted recognizable pancreatic tissue. Two cases were discarded on the basis of hepatocellular disease, and one case was discarded because of hepatic metastases. Thirty-two cases demonstrated pancreatic echogenicity greater than that of the liver, and 30 cases demonstrated pancreatic echogenicity equivalent to that of the liver. We found no normal pancreas that displayed less echogenicity than the liver. A hypothesis is offered to explain the observed results.

Acoustics↗

In vitro investigation of gallstone shadowing with ultrasound tomography.

A phantom was constructed to simulate the in vivo situation of gallstone detection. Gallstone specimens from 37 patients were scanned. All gallstones cast acoustic shadows, regardles of the specific properties of the stones. Experimental evidence concerning factors that affect the detection of acoustic shadows from gallstones is discussed.

Acoustics↗