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Biomedical subjects

R A Filly

Publications and source records attributed to R A Filly.

At least 253 records · Page 14Linked to original sources
PubMed1982

Sonography as a procedure complementary to alpha-fetoprotein testing for neural tube defects.

Forty-four fetuses were studied sonographically because of an elevated amniotic fluid alpha-fetoprotein level noted during routine amniocentesis, questionable findings during an ultrasound examination at another institution, or a history of a neural tube defect in prior pregnancy. Eleven neural tube defects, 16 non-neural tube defect anomalies, and 17 normal fetuses were all correctly identified by sonography. Ultrasound answers the need for a second diagnostic tool to complement the alpha-fetoprotein measurement.

Amniotic Fluid↗
PubMed1981

Management of the fetus with a urinary tract malformation.

Obstetric sonography revealed urinary tract malformations in 13 fetuses. Six had severe dysplastic lesions incompatible with postnatal life; in all six, oligohydramnios and inability to detect normal kidney or bladder allowed appropriate counseling and management. Four fetuses had unilateral lesions (three hydronephrotic, one multicystic); all had evidence of adequate contralateral function and were successfully treated after delivery near term. Three fetuses had bilateral hydronephrosis secondary to urethral obstruction. The two who were born near term died of hypoplastic lungs, end-stage hydronephrosis, and facial and skeletal deformities. The other, electively delivered at 32 weeks, had none of the stigmata of Potter's syndrome, and early decompression salvaged sufficient renal function for survival. Prenatal sonographic assessment of urinary tract anatomy and function can improve perinatal management. The fetus with hydronephrosis may benefit from early decompression.

Abnormalities, Multiple↗
PubMed1981

Prediction of intrauterine growth retardation by sonographic estimation of total intrauterine volume.

A group of 252 patients who had total intrauterine volume (TIUV) measurements after 20 weeks menstrual age were evaluated for prediction of growth retardation. The measurements were compared to previously published normal values derived at out institution. The birth weights of these patients' babies were evaluated by the California standard. Setting the threshold of an abnormal test at the lower 10% tolerance limit, the TIUV measurement was sensitive in 70%, specific in 72%, and accurate in predicting IUGR in only 41% of cases. Ultrasonic estimation of TIUV is limited as a predictor of IUGR.

Female↗
PubMed1981

Further observations on the sonographic spectrum of gestational trophoblastic disease.

Sonograms of 27 patients with gestational trophoblastic disease were evaluated and categorized to newer concepts regarding the pathology and pathogenesis of this disorder. The patients were assigned to the following subgroups: 1) classical or complete mole; 2) partial or incomplete mole; 3) coexistent mole and fetus; 4) hydropic degeneration of the placenta; 5) locally invasive mole; and 6) metastatic trophoblastic disease, including choriocarcinoma. The utility of this categorization and of ultrasound in the diagnosis and subsequent management of these patients is presented.

Adolescent↗
PubMed1981

Short-limbed dwarfism: ultrasonographic diagnosis by mensuration of fetal femoral length.

The femoral lengths of 70 normal fetuses, five short-limbed dwarfs, and two additional normal fetuses at risk for dwarfism were measured employing linear array real-time (rapid B-scan) ultrasonographic systems. Early results indicate that prenatal diagnosis of short-limbed dwarfs can be accomplished by this technique, in some instances early enough to allow parents to consider elective abortion. The data also indicate fundamental differences in the growth pattern of certain dwarf syndromes.

Dwarfism↗
PubMed1981

Rapid change in caliber of the nonobstructed common duct.

A case of a postcholecystectomy patient is presented in which an initially grossly dilated common hepatic duct returned to normal size within several minutes. We have tried to explain this phenomenon using known facts abut bile duct elasticity and bile flow, and conclude that such rapid size change probably only occurs in those patients without a normally functioning gallbladder.

Cholecystectomy↗
PubMed1981

Abdominal pseudotumor in childhood: distended gallbladder with parenteral hyperalimentation.

Two children receiving total parenteral hyperalimentation had palpable upper abdominal masses. Sonography showed these masses to be distended gallbladders. Sonograms of four other children receiving parenteral hyperalimentation were examined to determine if gallbladder distension in these cases was coincidental or common; three of four also had gallbladder distension. Follow-up sonograms after initiation of oral feedings in two children showed reduced gallbladder dimensions. Children can have palpable, distended gallbladders while fasting and receiving parenteral hyperalimentation. Sonography can differentiate distended gallbladders from other abdominal masses.

Abdominal Neoplasms↗
PubMed1981

Cystic hepatic neoplasms: complementary roles of CT and sonography.

Nine patients with cystic or necrotic hepatic neoplasms had findings on computed tomography (CT) that strongly suggested benign cystic disease of the liver. Sonography depicted the true morphology of these cystic lesions more clearly than CT, and the sonographic findings virtually excluded uncomplicated hepatic cyst as a diagnosis. Important observations were wall thickness, mural nodules, septations, and fluid-fluid levels. The potential danger in over reliance on CT attenuation values and the complementary role of sonography and CT in such cases are stressed.

Adult↗