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Biomedical subjects

P Probst

Publications and source records attributed to P Probst.

At least 181 records · Page 10Linked to original sources
PubMed1977

[Two rare cases of neovascularity on coronary angiography (author's transl)].

The appearance of neovascularity on coronary angiography is described in two patients. A large thrombus was documented in one case at autopsy, whilst in the second case the presence of a thrombus was confirmed by two subsequent coronary arteriographic and ventriculographic studies. Thus, the observation of neovascularity of the left ventricle on angiography is indicative of thrombus formation rather than the presence of a neoplasm.

Angiocardiography↗
PubMed1977

Pre-excitation of the ventricle associated with total intra His bundle block.

A case with total intra-His bundle block and intermittent pre-excitation syndrome is presented. During A-V conduction there was a P-delta interval of 130 msec. with a P-A interval of 20 msec., an A-H interval of 60 msec. and an H-V interval of 50 msec. During rapid atrial pacing the P-delta interval increased primarily due to an A-H1 prolongation and a Mobitz type 2 block and total A-V block occured at increasing rates showing H1 following every A spike. The escape beats showed a normal width of the QRS complexes with preceding H2 spikes. After administration of Ajmaline the bypass tract was blocked and constant total A-V block occurred. It was concluded that there was a constant total intra-His bundle block and a nodoventricular or fasciculoventricular bypass tract with prolonged conduction to the ventricle. This bypass tract blocked sometimes spontaneously and could also be blocked by rapid atrial pacing and administration of drugs. The close anatomic proximity of the His bundle and Mahaim fibers is responsible for the simultaneous block resulting in total atrioventricular block.

Aged↗
PubMed1977

[Myocardial infarct with a normal coronary angiogram].

The present report describes a case of a massive transmural anterior wall myocardial infarction in a woman with angiographically normal coronary arteries. The possible mechanisms of production of myocardial infarction in the presence of normal coronary arteriograms are discussed. With the increasing application of coronary arteriography, such diagnostic problems will undoubtedly become more frequent.

Angiography↗
PubMed1976

[Thrombocytopenia in hepatitis-B-antigenemia (author's transl)].

Determination of hepatitis-B-antigen and thrombocytes in 1488 cases of liver diseases, 173 of whom had been treated with immunsuppressive drugs. There was no significant relation between hepatitis-B-antigenemia and thrombocyte-count, nor could an influence of the immunsuppressive therapy be evaluated. The thrombocyte-count was correlated with high significance only to the degree of the liver injury.

Azathioprine↗
PubMed1976

[Diastolic murmurs in atrial septal defect (author's transl)].

No correlation was found between the presence of a diastolic murmur in about 50% of patients with artrial septal defect and the calculated shunt volume. A significant correlation was found in respect to the age of the patient, the majority of the murmurs being found in young patients and especially in young patients with tachycardia. Similar murmurs were found in healthy persons and, hence, a functional stenosis of the AV-valve ring could be the reason for this diastolic murmur, which may occur more frequently in patients with atrial septal defect on account of an alteration in the blood stream patterns.

Adolescent↗
PubMed1976

[The angiographic morphology of arterial injury (author's transl)].

The angiographic morphology for various arterial injuries is described and illustrated by means of 46 patients examined by us; these consisted of 13 socclusions, 21 arterial rupture and 12 arterial lacerations. The main angiographic feature is thrombotic occlusion of the damaged artery. Consequently, the pathology of the arterial lesion could be defined in only one third of the patients with arterial injuries. This, however, is not of major importance in planning vascular surgery.

Aneurysm↗
PubMed1976

[Influence of propafenon on hemodynamics of the left ventricle and atrioventricular conduction with special reference to the WPW syndrome].

15 patients were injected 2 mg/kg Propafenon intravenously in 3 minutes. In 10 patients the changes of the atrio-ventricular conduction and the sinus-node recovery time were measured. In 5 out of these 10 patients the influence on the left ventricular systolic pressure, the left ventricular enddiastolic pressure and the dp/dtmax was also measured. 4 patients had a WPW-syndrom and one patient an AV nodal tachycardia. There was a significant increase of the PQ-time (16,7%), the AH interval (9%), HV interval (33%) and the width of the QRS complex (13.8%). The intratrial conduction (PA-time), the heart rate and the sinus-node recovery time were not influenced. In 6 out of 7 patients the effective refractory period of the AV node was prolonged and in one it remained unchanged. There was a statistically significant decrease of the dp/dt, the heart rate staying the same. The systolic pressure decreased slightly and the enddiastolic pressure increased insignificantly. In 3 out of 4 patients with WPW syndrome the accessory pathway was blocked and in the 4th the effective refractory period of the pathway prolonged. In 3 out of these 4 patients a tachycardia could be initiated by the extra-stimulus method which was not possible after administration of the drug.

Adult↗
PubMed1976

[Corelations between thrombocyte count, clinical diagnosis, and liver pathology in chronic liver diseases].

In 1488 cases of chronic liver disease thrombocyte content of peripheral blood, clinical diagnosis and histologic findings of the liver biopsy were correlated. Ranging from fatty infiltration to fatty cirrhosis or from slightly active chronic hepatitis to active postnecrotic cirrhosis, according to the extent of the liver injury a significant decrease of thrombocyte-count was evaluated. In case of non-active liver disease and posthepatitic status a thrombocytopenia also could be found. Cirrhotic transformation or proliferation of the connective tissue mainly in the periportal fields and inflammatory activity showed a significant correlation to the frequency of a thrombocyte decrease. A pathogenetic relation is ascribed to an increased thrombocyte storage in the spleen depending on the extent of the liver injury and the alteration of the portal blood stream up to a portal hypertension. Our results indicate such correlations of liver injury, portal pressure and platelet-pooling to thrombocyte-count even if the causal dependency cannot be proved.

Adult↗