[Reduction of operative risk by HFJV in endobronchial cryotherapy].
Explore the source record for details and available documents.
Biomedical subjects
Publications and source records attributed to P Lamy.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Five cases of epithelioid hemangioendothelioma of the liver are reported. This unusual type of vascular tumor is often difficult to diagnose; its angiogenic nature is not overt at the radiologic level and may be overlooked by conventional histologic examination. At imaging procedures, epithelioid hemangioendothelioma of the liver presents as multiple focal hypovascular areas, disseminated in both lobes. The combination of these imaging abnormalities with a peculiar set of demographic and clinical features, including young age, good general condition, and progressive course, is suggestive. However, the final diagnosis can be established only by histologic examination of appropriate material collected by guided liver biopsies and may be helped by immunohistochemistry and ultrastructural examination. The accurate diagnosis of epithelioid hemangioendothelioma of the liver is of clinical and therapeutic relevance. In view of its favorable clinical course, orthotopic liver transplantation may be considered for the treatment of this tumor when intrahepatic dissemination contraindicates partial hepatectomy and extrahepatic extension, excluded by exploratory laparotomy, is absent.
Fever, dyspnea, dry cough and interstitial fibrosis occurred in a man with prostate carcinoma treated with nilutamide and buserelin for two and one-half months. The diagnosis of drug-induced fibrosis was established on the basis of chronologic and semiologic events. This is the first such case reported.
We report the case of a patient with primary sclerosing cholangitis associated with systemic lupus erythematosus. Only one similar case has been previously reported. The relationship between the two diseases is discussed.
Explore the source record for details and available documents.
The progression of bronchial cancer results in death due to local complications in more than one third of cases and systemic treatment often needs to be completed by disobstruction procedures which restore the continuity of the bronchial lumen and palliate the severe complications, in particular respiratory failure and bronchial infections. The techniques are described in detail: bronchoscopy, endoscopic resection with various types of forceps, diathermy loops and, most importantly, laser. A series of 99 disobstruction procedures performed in 47 patients is presented.
The authors report 8 new cases of granular cell tumour of Abrikossoff's tumour located in the trachea or bronchus. After briefly recalling the generally accepted features of this disease, they report several new aspects: the obviously under-estimated frequency, the absence of progression, requiring therapeutic abstention and regular follow-up, the epidemiological problems posed by the association with chronic bronchitis or the coexistence with a malignant bronchial tumour, the uncertainties which still surround the histogenesis, which is partly mesenchymal and partly nervous tissue, more particularly Schwann cells, which can be supported by ultrastructural arguments.
Bone surveys represent a particular problem in the investigation of secondary tumours, especially in the case of small cell cancer. This study was based on 70 patients in which qualitative criteria (clinical, radiographic, bone scan, bone aspiration-biopsy) replaced quantitative criteria (calcium, alkaline phosphatase, phosphorus). The histological (BPO) and clinical (pain) markers were determinant in the prognosis; in contrast, the repetition of the bone scan in the evaluation of response to treatment is only of very limited value.
The authors present 52 cases of neurological complications of bronchial cancer including 35 cases of non-tumoral manifestations. They stress the frequency and the severity of these complications which are dominated by cerebral vascular accidents and describe the pathogenic features of this particular complication. They define the complications accessible to treatment: iatrogenic pathology, deficiency disorders and certain paraneoplasic syndromes.
Up until now, adrenal metastases from bronchial cancer have always been an autopsy diagnosis with a frequency as high as 45%. These metastases can now be diagnosed by means of computed tomography of the adrenal glands and most of the recent studies report an incidence of 10 to 15% of adrenal metastases independently of the histological type of bronchial cancer. The authors stress the need to perform this examination in the context of pre-treatment staging and for the follow-up of bronchial cancer. The outcome of these adrenal metastases is still poorly understood, but prospective studies could provide more information concerning their prognostic significance. In cases of operable bronchial carcinoma with an isolated adrenal metastasis, it is important to be able to detect this lesion which may be able to be excised prior to the thoracic surgery.
This study is based on the analysis of the radiological and histological features of the lymph nodes in 167 operated cases of bronchial carcinoma. The conventional evaluation by means of radiography demonstrates the difficulty of accurately diagnosing lymph node involvement; these investigations are simply able to reveal the presence or absence of enlarged lymph nodes without being able to distinguish between neoplastic and purely inflammatory lymphadenopathy. Histological examination demonstrates the presence of hilar and mediastinal node involvement: the first does not influence the survival in contrast with the second which seems to reflect an intense immune response.
On the basis of 81 cases of surgical lung biopsy performed in the course of diffuse interstitial lung disease, the authors report the yield and the tolerance which they observed with this technique in comparison with data from the literature. Like other authors, they obtained an excellent histological yield, as only one case was uninterpretable in this present series. However, they emphasise the "final yield", which consists of a precise aetiological diagnosis, i.e. the exclusion of the diagnosis of diffuse interstitial fibrosis. The analysis of the tolerance of the procedure revealed a higher morbidity and mortality than those generally reported in the literature.
The authors report an unusual case of unilateral obstruction of the pulmonary veins in an adult and discuss the elements of the pre-operative diagnosis. They recall the pathophysiological and therapeutic consequences of this disease.
The scimitar sign, characterised by a vertical opacity crossing the medial part of the right diaphragm, is generally attributed to abnormal pulmonary venous return draining into the inferior vena cava. This is not the only situation in which the scimitar sign is observed, which can also be seen in association with systemic anomalies, in particular sequestration. The authors report the case of a young adult in whom the chest x-ray presented the scimitar sign from childhood. This image was related to a pure pulmonary vessel sequestration by a right sub-phrenic artery. The authors stress the possibility of a purely arterial origin for the scimitar sign in the absence of any abnormality of pulmonary venous return.
The authors report a study conducted in 167 cases of primary bronchial carcinoma, in which 6 tumour markers were assayed: carcinoembryonic antigen, alpha-1-foetoprotein, ACTH, parathormone, thyrocalcitonin, and beta-HCG. The statistical analysis of their results suggests that these markers are of limited value in routine practice. They discuss the development of the ideas on this subject and try to explain a certain number of controversies.
The pulmonary veins are rarely the subject of an autonomous and complete study. In fact they have given rise to very few works in comparison with the neighbouring structures and their pathology seems to be rare and heterogeneous. The present article deals with the fundamental points about the normal pulmonary veins and the different aspects of their pathology.